Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6RN4

ClpB (DWB mutant) bound to casein in presence of ATPgammaS - state WT-2B

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0009408	biological_process	response to heat
A	0016887	molecular_function	ATP hydrolysis activity
A	0042026	biological_process	protein refolding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0009408	biological_process	response to heat
B	0016887	molecular_function	ATP hydrolysis activity
B	0042026	biological_process	protein refolding
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0009408	biological_process	response to heat
C	0016887	molecular_function	ATP hydrolysis activity
C	0042026	biological_process	protein refolding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0009408	biological_process	response to heat
D	0016887	molecular_function	ATP hydrolysis activity
D	0042026	biological_process	protein refolding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0009408	biological_process	response to heat
E	0016887	molecular_function	ATP hydrolysis activity
E	0042026	biological_process	protein refolding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0009408	biological_process	response to heat
F	0016887	molecular_function	ATP hydrolysis activity
F	0042026	biological_process	protein refolding

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue AGS A 1001

Chain	Residue
A	VAL180
A	ILE349
A	PRO387
A	ILE391
F	ARG331
A	ILE181
A	PRO208
A	GLY209
A	VAL210
A	GLY211
A	LYS212
A	THR213
A	ALA214

site_id	AC2
Number of Residues	16
Details	binding site for residue AGS B 1001

Chain	Residue
A	ARG331
A	ARG332
B	ASP178
B	PRO179
B	VAL180
B	ILE181
B	PRO208
B	GLY209
B	GLY211
B	LYS212
B	THR213
B	ALA214
B	ILE349
B	PRO387
B	ASP388
B	ILE391

site_id	AC3
Number of Residues	14
Details	binding site for residue AGS B 1002

Chain	Residue
B	ARG569
B	VAL570
B	ILE571
B	GLY572
B	GLY608
B	VAL609
B	GLY610
B	LYS611
B	THR612
B	GLU613
B	ILE774
B	ALA814
B	ARG815
B	LYS818

site_id	AC4
Number of Residues	15
Details	binding site for residue AGS C 1001

Chain	Residue
B	ARG331
B	ARG332
C	PRO179
C	VAL180
C	ILE181
C	PRO208
C	GLY209
C	GLY211
C	LYS212
C	THR213
C	ALA214
C	ILE349
C	LEU353
C	PRO387
C	ASP388

site_id	AC5
Number of Residues	16
Details	binding site for residue AGS C 1002

Chain	Residue
B	ARG756
C	ARG569
C	VAL570
C	ILE571
C	THR607
C	GLY608
C	VAL609
C	GLY610
C	LYS611
C	THR612
C	GLU613
C	ASP677
C	ASN719
C	ALA814
C	ARG815
C	LYS818

site_id	AC6
Number of Residues	41
Details	binding site for Di-peptide AGS D 1001 and ARG C 332

Chain	Residue
D	GLY209
D	VAL210
D	GLY211
D	LYS212
D	THR213
D	ALA214
D	LYS300
D	ALA328
D	LEU329
D	GLU330
D	ARG331
D	PHE333
D	ILE349
D	LEU353
D	PRO387
E	AGS1001
B	ARG331
B	ARG332
C	PRO179
C	VAL180
C	ILE181
C	ASN201
C	PRO208
C	GLY209
C	GLY211
C	LYS212
C	THR213
C	ALA214
C	LYS300
C	ALA304
C	ALA328
C	GLU330
C	ARG331
C	PHE333
C	ILE349
C	LEU353
C	PRO387
C	ASP388
D	ASP178
D	VAL180
D	ILE181

site_id	AC7
Number of Residues	14
Details	binding site for Di-peptide AGS D 1001 and GLY D 211

Chain	Residue
C	ARG331
C	ARG332
D	ASP178
D	VAL180
D	ILE181
D	GLY209
D	VAL210
D	LYS212
D	THR213
D	ALA214
D	ILE215
D	ILE349
D	LEU353
D	PRO387

site_id	AC8
Number of Residues	18
Details	binding site for Di-peptide AGS D 1002 and THR D 607

Chain	Residue
C	ARG756
D	ARG569
D	VAL570
D	ILE571
D	GLY605
D	PRO606
D	GLY608
D	VAL609
D	GLY610
D	LYS611
D	THR612
D	GLU613
D	ASN719
D	ILE774
D	GLN778
D	ALA814
D	ARG815
D	LYS818

site_id	AC9
Number of Residues	12
Details	binding site for Di-peptide AGS E 1001 and VAL E 210

Chain	Residue
D	ARG331
D	ARG332
E	ILE181
E	GLU207
E	PRO208
E	GLY209
E	GLY211
E	LYS212
E	THR213
E	ILE349
E	LEU353
E	PRO387

site_id	AD1
Number of Residues	15
Details	binding site for Di-peptide AGS E 1002 and ILE E 571

Chain	Residue
D	ASP695
E	ARG569
E	VAL570
E	GLY572
E	THR607
E	GLY608
E	VAL609
E	GLY610
E	LYS611
E	THR612
E	GLU613
E	ILE774
E	ALA814
E	ARG815
E	LYS818

site_id	AD2
Number of Residues	16
Details	binding site for Di-peptide AGS E 1002 and VAL E 609

Chain	Residue
D	ASP695
E	ARG569
E	VAL570
E	ILE571
E	GLY572
E	PRO606
E	THR607
E	GLY608
E	GLY610
E	LYS611
E	THR612
E	GLU613
E	ILE774
E	ALA814
E	ARG815
E	LYS818

site_id	AD3
Number of Residues	22
Details	binding site for Di-peptide AGS E 1002 and LYS E 611

Chain	Residue
D	ASP695
E	ARG569
E	VAL570
E	ILE571
E	GLY572
E	LEU604
E	GLY605
E	PRO606
E	THR607
E	GLY608
E	VAL609
E	GLY610
E	THR612
E	GLU613
E	LEU614
E	CYS615
E	SER718
E	PHE763
E	ILE774
E	ALA814
E	ARG815
E	LYS818

site_id	AD4
Number of Residues	15
Details	binding site for Di-peptide AGS F 1001 and LEU F 766

Chain	Residue
F	ILE571
F	THR607
F	GLY608
F	VAL609
F	GLY610
F	LYS611
F	HIS764
F	PRO765
F	GLY767
F	HIS770
F	ILE771
F	ILE774
F	TYR808
F	ALA814
F	ARG815

site_id	AD5
Number of Residues	11
Details	binding site for Di-peptide AGS F 1001 and GLY F 608

Chain	Residue
F	ILE571
F	THR607
F	VAL609
F	GLY610
F	LYS611
F	LEU766
F	HIS770
F	ILE774
F	TYR812
F	ALA814
F	ARG815

site_id	AD6
Number of Residues	13
Details	binding site for Di-peptide AGS F 1001 and THR F 607

Chain	Residue
F	ILE571
F	PRO606
F	GLY608
F	VAL609
F	GLY610
F	LYS611
F	LEU766
F	HIS770
F	ILE774
F	VAL811
F	TYR812
F	ALA814
F	ARG815

site_id	AD7
Number of Residues	14
Details	binding site for Di-peptide AGS F 1001 and ILE F 571

Chain	Residue
F	ARG569
F	VAL570
F	GLY572
F	THR607
F	GLY608
F	VAL609
F	GLY610
F	LYS611
F	LEU766
F	HIS770
F	SER773
F	ILE774
F	ALA814
F	ARG815

site_id	AD8
Number of Residues	15
Details	binding site for Di-peptide AGS F 1001 and ALA F 814

Chain	Residue
F	ILE571
F	THR607
F	GLY608
F	VAL609
F	GLY610
F	LYS611
F	LEU766
F	HIS770
F	ILE774
F	TYR812
F	GLY813
F	ARG815
F	PRO816
F	LEU817
F	LYS818

site_id	AD9
Number of Residues	18
Details	binding site for Di-peptide ADP F 1002 and PRO F 387

Chain	Residue
E	GLU330
F	VAL180
F	ILE181
F	GLU207
F	PRO208
F	GLY209
F	VAL210
F	GLY211
F	LYS212
F	THR213
F	ALA214
F	ILE349
F	GLN385
F	LEU386
F	ASP388
F	LYS389
F	ALA390
F	ILE391

site_id	AE1
Number of Residues	20
Details	binding site for Di-peptide ADP F 1002 and ILE F 349

Chain	Residue
E	GLU330
F	VAL180
F	ILE181
F	GLU207
F	PRO208
F	GLY209
F	VAL210
F	GLY211
F	LYS212
F	THR213
F	ALA214
F	ASP345
F	THR346
F	ILE347
F	ALA348
F	LEU350
F	ARG351
F	GLY352
F	LEU353
F	PRO387

site_id	AE2
Number of Residues	14
Details	binding site for Di-peptide ADP F 1002 and VAL F 210

Chain	Residue
E	GLU330
F	VAL180
F	ILE181
F	GLU207
F	PRO208
F	GLY209
F	GLY211
F	LYS212
F	THR213
F	ALA214
F	ILE349
F	GLN385
F	LEU386
F	PRO387

site_id	AE3
Number of Residues	13
Details	binding site for Di-peptide ADP F 1002 and GLY F 209

Chain	Residue
E	GLU330
F	VAL180
F	ILE181
F	GLU207
F	PRO208
F	VAL210
F	GLY211
F	LYS212
F	THR213
F	ALA214
F	ILE349
F	LEU386
F	PRO387

Functional Information from PROSITE/UniProt

site_id	PS00870
Number of Residues	13
Details	CLPAB_1 Chaperonins clpA/B signature 1. DAGNMLKPaLarG

Chain	Residue	Details
A	ASP294-GLY306

site_id	PS00871
Number of Residues	19
Details	CLPAB_2 Chaperonins clpA/B signature 2. RIDmSEFmEKhSvSRLvGA

Chain	Residue	Details
A	ARG631-ALA649

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)