6RLU
Trypanosoma brucei Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)cytidine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004828 | molecular_function | serine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005829 | cellular_component | cytosol |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006434 | biological_process | seryl-tRNA aminoacylation |
| A | 0016874 | molecular_function | ligase activity |
| A | 0070158 | biological_process | mitochondrial seryl-tRNA aminoacylation |
| B | 0000049 | molecular_function | tRNA binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004828 | molecular_function | serine-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005829 | cellular_component | cytosol |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006434 | biological_process | seryl-tRNA aminoacylation |
| B | 0016874 | molecular_function | ligase activity |
| B | 0070158 | biological_process | mitochondrial seryl-tRNA aminoacylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 501 |
| Chain | Residue |
| A | GLY137 |
| A | ASN138 |
| A | ILE139 |
| A | GLN397 |
| A | HOH602 |
| A | HOH622 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 502 |
| Chain | Residue |
| A | MET181 |
| A | ASP182 |
| A | THR183 |
| A | SER184 |
| A | HOH731 |
| A | ASN170 |
| A | SER173 |
| A | GLU176 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 503 |
| Chain | Residue |
| A | THR223 |
| A | LEU285 |
| A | LYS286 |
| A | TYR287 |
| A | HOH605 |
| A | HOH610 |
| A | HOH632 |
| A | HOH701 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 504 |
| Chain | Residue |
| A | TYR272 |
| A | HIS273 |
| A | ARG276 |
| A | TYR287 |
| A | HOH605 |
| B | LYS199 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 505 |
| Chain | Residue |
| A | GLU384 |
| A | SER387 |
| A | FZQ507 |
| A | HOH676 |
| A | HOH898 |
| A | HOH901 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 506 |
| Chain | Residue |
| A | ASN170 |
| A | SER379 |
| A | HOH879 |
| A | HOH914 |
| site_id | AC7 |
| Number of Residues | 19 |
| Details | binding site for residue FZQ A 507 |
| Chain | Residue |
| A | THR264 |
| A | GLU266 |
| A | ARG295 |
| A | GLU297 |
| A | VAL311 |
| A | PHE314 |
| A | GLU318 |
| A | GLU384 |
| A | LEU385 |
| A | VAL386 |
| A | SER387 |
| A | ASN423 |
| A | THR425 |
| A | ALA428 |
| A | ARG431 |
| A | NA505 |
| A | HOH654 |
| A | HOH785 |
| A | HOH810 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | binding site for residue GOL B 501 |
| Chain | Residue |
| A | THR164 |
| A | LYS165 |
| A | ARG166 |
| B | TRP277 |
| B | THR279 |
| B | GLY404 |
| B | ASN406 |
| B | HOH632 |
| B | HOH651 |
| B | HOH704 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 502 |
| Chain | Residue |
| B | GLY137 |
| B | ASN138 |
| B | ILE139 |
| B | GLN397 |
| B | HOH602 |
| B | HOH624 |
| site_id | AD1 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 503 |
| Chain | Residue |
| A | ARG166 |
| A | ALA167 |
| A | HOH827 |
| B | ARG276 |
| B | TRP277 |
| B | PHE278 |
| B | GOL504 |
| B | HOH668 |
| B | HOH853 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 504 |
| Chain | Residue |
| A | LYS199 |
| B | TYR272 |
| B | HIS273 |
| B | ARG276 |
| B | TYR287 |
| B | GOL503 |
| B | HOH681 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 505 |
| Chain | Residue |
| B | THR223 |
| B | LEU285 |
| B | LYS286 |
| B | TYR287 |
| B | HOH618 |
| B | HOH681 |
| B | HOH716 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 506 |
| Chain | Residue |
| B | HOH619 |
| B | HOH821 |
| B | HOH822 |
| B | GLU384 |
| B | SER387 |
| B | FZQ510 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 507 |
| Chain | Residue |
| B | LEU407 |
| B | THR410 |
| B | GLN413 |
| B | HOH685 |
| B | HOH898 |
| B | HOH915 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue NA B 508 |
| Chain | Residue |
| A | HOH862 |
| B | ASN162 |
| B | THR164 |
| B | HOH823 |
| B | HOH861 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue NA B 509 |
| Chain | Residue |
| B | ASN170 |
| B | SER379 |
| B | HOH893 |
| B | HOH903 |
| site_id | AD8 |
| Number of Residues | 19 |
| Details | binding site for residue FZQ B 510 |
| Chain | Residue |
| B | THR264 |
| B | GLU266 |
| B | ARG295 |
| B | GLU297 |
| B | VAL311 |
| B | PHE314 |
| B | GLU318 |
| B | GLU384 |
| B | LEU385 |
| B | VAL386 |
| B | SER387 |
| B | ASN423 |
| B | THR425 |
| B | ALA428 |
| B | ARG431 |
| B | NA506 |
| B | HOH620 |
| B | HOH802 |
| B | HOH808 |
| site_id | AD9 |
| Number of Residues | 7 |
| Details | binding site for residue MLI B 511 |
| Chain | Residue |
| B | ARG402 |
| B | ASN406 |
| B | LEU407 |
| B | ARG408 |
| B | HOH706 |
| B | HOH809 |
| B | HOH816 |
