6RFX
Crystal structure of Eis2 from Mycobacterium abscessus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008080 | molecular_function | N-acetyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| A | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| B | 0008080 | molecular_function | N-acetyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| B | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| C | 0008080 | molecular_function | N-acetyltransferase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016746 | molecular_function | acyltransferase activity |
| C | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| C | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| D | 0008080 | molecular_function | N-acetyltransferase activity |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016746 | molecular_function | acyltransferase activity |
| D | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| D | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| E | 0008080 | molecular_function | N-acetyltransferase activity |
| E | 0016740 | molecular_function | transferase activity |
| E | 0016746 | molecular_function | acyltransferase activity |
| E | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| E | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
| F | 0008080 | molecular_function | N-acetyltransferase activity |
| F | 0016740 | molecular_function | transferase activity |
| F | 0016746 | molecular_function | acyltransferase activity |
| F | 0030649 | biological_process | aminoglycoside antibiotic catabolic process |
| F | 0034069 | molecular_function | aminoglycoside N-acetyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue CIT D 501 |
| Chain | Residue |
| D | ARG90 |
| D | HOH673 |
| D | ARG91 |
| D | ARG92 |
| D | GLY93 |
| D | LEU95 |
| D | THR96 |
| D | ARG126 |
| D | PHE127 |
| D | HOH664 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue P4K D 502 |
| Chain | Residue |
| D | MSE19 |
| D | ALA22 |
| D | PHE26 |
| D | HOH644 |
| D | HOH771 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue ACT D 503 |
| Chain | Residue |
| D | SER64 |
| D | ARG65 |
| D | HIS66 |
| D | THR188 |
| D | TRP191 |
| D | HOH639 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue CIT A 501 |
| Chain | Residue |
| A | ARG90 |
| A | ARG91 |
| A | ARG92 |
| A | GLY93 |
| A | LEU94 |
| A | LEU95 |
| A | THR96 |
| A | ARG126 |
| A | PHE127 |
| A | HOH730 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue P4K A 502 |
| Chain | Residue |
| A | MSE19 |
| A | TYR23 |
| A | PHE26 |
| A | ASP410 |
| A | HOH729 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue ACT A 503 |
| Chain | Residue |
| A | SER64 |
| A | ARG65 |
| A | HIS66 |
| A | TRP191 |
| A | HOH666 |
| A | HOH713 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue P4K A 504 |
| Chain | Residue |
| A | GLN279 |
| A | ALA396 |
| A | TRP401 |
| A | HOH622 |
| D | GLN279 |
| D | GLY371 |
| D | SER374 |
| D | ALA396 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | binding site for residue CIT B 501 |
| Chain | Residue |
| B | ARG90 |
| B | ARG91 |
| B | ARG92 |
| B | GLY93 |
| B | LEU95 |
| B | THR96 |
| B | ARG126 |
| B | PHE127 |
| B | HOH633 |
| B | HOH706 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue P4K B 502 |
| Chain | Residue |
| B | MSE19 |
| B | ALA22 |
| B | TYR23 |
| B | PHE26 |
| B | ASP410 |
| B | HOH788 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue ACT B 503 |
| Chain | Residue |
| B | SER64 |
| B | ARG65 |
| B | HIS66 |
| B | TRP191 |
| B | HOH647 |
| site_id | AD2 |
| Number of Residues | 10 |
| Details | binding site for residue P4K B 504 |
| Chain | Residue |
| B | GLN279 |
| B | GLY371 |
| B | SER374 |
| B | TRP401 |
| B | PRO402 |
| B | HOH649 |
| C | GLN279 |
| C | GLY371 |
| C | SER374 |
| C | ALA396 |
| site_id | AD3 |
| Number of Residues | 9 |
| Details | binding site for residue CIT C 501 |
| Chain | Residue |
| C | ARG90 |
| C | ARG91 |
| C | ARG92 |
| C | GLY93 |
| C | LEU95 |
| C | THR96 |
| C | ARG126 |
| C | PHE127 |
| C | HOH663 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue P4K C 502 |
| Chain | Residue |
| C | ALA22 |
| C | TYR23 |
| C | PHE26 |
| C | ASP410 |
| C | HOH819 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue ACT C 503 |
| Chain | Residue |
| C | HOH645 |
| C | SER64 |
| C | ARG65 |
| C | HIS66 |
| C | HOH640 |
| site_id | AD6 |
| Number of Residues | 10 |
| Details | binding site for residue CIT E 501 |
| Chain | Residue |
| E | ARG90 |
| E | ARG91 |
| E | ARG92 |
| E | GLY93 |
| E | LEU95 |
| E | THR96 |
| E | ARG126 |
| E | PHE127 |
| E | HOH607 |
| E | HOH679 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue P4K E 502 |
| Chain | Residue |
| E | MSE19 |
| E | TYR23 |
| E | PHE26 |
| site_id | AD8 |
| Number of Residues | 8 |
| Details | binding site for residue ACT E 503 |
| Chain | Residue |
| E | SER64 |
| E | ARG65 |
| E | HIS66 |
| E | THR188 |
| E | TRP191 |
| E | HOH616 |
| E | HOH633 |
| E | HOH671 |
| site_id | AD9 |
| Number of Residues | 8 |
| Details | binding site for residue CIT F 501 |
| Chain | Residue |
| F | ARG90 |
| F | ARG91 |
| F | ARG92 |
| F | GLY93 |
| F | LEU95 |
| F | THR96 |
| F | ARG126 |
| F | PHE127 |
