6RFL

Structure of the complete Vaccinia DNA-dependent RNA polymerase complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003899	molecular_function	DNA-directed RNA polymerase activity
A	0006351	biological_process	DNA-templated transcription
B	0003677	molecular_function	DNA binding
B	0003899	molecular_function	DNA-directed RNA polymerase activity
B	0006351	biological_process	DNA-templated transcription
B	0032549	molecular_function	ribonucleoside binding
C	0003677	molecular_function	DNA binding
C	0003899	molecular_function	DNA-directed RNA polymerase activity
C	0019083	biological_process	viral transcription
E	0003677	molecular_function	DNA binding
E	0003899	molecular_function	DNA-directed RNA polymerase activity
E	0019083	biological_process	viral transcription
F	0003677	molecular_function	DNA binding
F	0003899	molecular_function	DNA-directed RNA polymerase activity
F	0006351	biological_process	DNA-templated transcription
G	0003677	molecular_function	DNA binding
G	0003899	molecular_function	DNA-directed RNA polymerase activity
G	0019083	biological_process	viral transcription
I	0003700	molecular_function	DNA-binding transcription factor activity
I	0006351	biological_process	DNA-templated transcription
I	0006353	biological_process	DNA-templated transcription termination
I	0006355	biological_process	regulation of DNA-templated transcription
I	0044423	cellular_component	virion component
I	0046872	molecular_function	metal ion binding
J	0003677	molecular_function	DNA binding
J	0003899	molecular_function	DNA-directed RNA polymerase activity
J	0006351	biological_process	DNA-templated transcription
K	0045893	biological_process	positive regulation of DNA-templated transcription
L	0004482	molecular_function	mRNA 5'-cap (guanine-N7-)-methyltransferase activity
L	0006370	biological_process	7-methylguanosine mRNA capping
O	0004482	molecular_function	mRNA 5'-cap (guanine-N7-)-methyltransferase activity
O	0004484	molecular_function	mRNA guanylyltransferase activity
O	0004651	molecular_function	polynucleotide 5'-phosphatase activity
O	0050355	molecular_function	inorganic triphosphate phosphatase activity
S	0003676	molecular_function	nucleic acid binding
S	0003677	molecular_function	DNA binding
S	0003899	molecular_function	DNA-directed RNA polymerase activity
S	0006351	biological_process	DNA-templated transcription
S	0008270	molecular_function	zinc ion binding
Y	0005524	molecular_function	ATP binding
Y	0006351	biological_process	DNA-templated transcription
Y	0017111	molecular_function	ribonucleoside triphosphate phosphatase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN B 1201

Chain	Residue
B	CYS1087
B	CYS1090
B	CYS1103
B	CYS1106

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site_id	AC2
Number of Residues	4
Details	binding site for residue ZN I 801

Chain	Residue
I	CYS326
I	HIS328
I	CYS363
I	CYS366

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site_id	AC3
Number of Residues	3
Details	binding site for residue MG A 1301

Chain	Residue
A	ASP417
A	ASP419
A	ASP415

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site_id	AC4
Number of Residues	4
Details	binding site for residue ZN A 1302

Chain	Residue
A	CYS49
A	CYS52
A	CYS59
A	HIS62

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site_id	AC5
Number of Residues	4
Details	binding site for residue ZN A 1303

Chain	Residue
A	CYS90
A	CYS93
A	CYS130
A	CYS135

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Functional Information from PROSITE/UniProt

site_id	PS00466
Number of Residues	36
Details	ZF_TFIIS_1 Zinc finger TFIIS-type signature. CpnCksrnttpmmIQTRAaDEPplvrhaCrd...CkqhF

Chain	Residue	Details
S	CYS159-PHE194

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site_id	PS01166
Number of Residues	13
Details	RNA_POL_BETA RNA polymerases beta chain signature. GdKFTTrTSQKGT

Chain	Residue	Details
B	GLY880-THR892

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