6RCN

Crystal structure of REXO2-D199A-dAdA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000175	molecular_function	3'-5'-RNA exonuclease activity
A	0003676	molecular_function	nucleic acid binding
B	0000175	molecular_function	3'-5'-RNA exonuclease activity
B	0003676	molecular_function	nucleic acid binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue ZN A 301

Chain	Residue
A	GLU49
A	HIS194
C	DA2

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site_id	AC2
Number of Residues	6
Details	binding site for residue MG A 302

Chain	Residue
A	ASP47
A	LEU48
A	ASP147
A	HOH411
C	DA1
C	DA2

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:31588022, ECO:0007744|PDB:6J7Y, ECO:0007744|PDB:6RCN

Chain	Residue	Details
A	GLN85
A	ASP87
B	GLN85
B	ASP87

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:31588022, ECO:0007744|PDB:6RCN

Chain	Residue	Details
A	GLU185
B	GLU185

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site_id	SWS_FT_FI3
Number of Residues	6
Details	SITE: Important for dinucleotide binding => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:32365187

Chain	Residue	Details
A	ASP91
A	PRO134
A	GLU202
B	ASP91
B	PRO134
B	GLU202

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site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	GLN130
B	GLN130

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site_id	SWS_FT_FI5
Number of Residues	2
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:15592455

Chain	Residue	Details
A	LYS160
B	LYS160

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site_id	SWS_FT_FI6
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q9D8S4

Chain	Residue	Details
A	ARG211
B	ARG211

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