6RCN

Crystal structure of REXO2-D199A-dAdA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000175	molecular_function	3'-5'-RNA exonuclease activity
A	0003676	molecular_function	nucleic acid binding
B	0000175	molecular_function	3'-5'-RNA exonuclease activity
B	0003676	molecular_function	nucleic acid binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue ZN A 301

Chain	Residue
A	GLU49
A	HIS194
C	DA2

---

site_id	AC2
Number of Residues	6
Details	binding site for residue MG A 302

Chain	Residue
A	ASP47
A	LEU48
A	ASP147
A	HOH411
C	DA1
C	DA2

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	164
Details	Domain: {"description":"Exonuclease"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"evidences":[{"source":"PubMed","id":"30926754","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31588022","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30926754","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31588022","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6J7Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RCN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30926754","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31588022","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6RCN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30926754","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6J7Y","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	5
Details	Site: {"description":"Important for dinucleotide binding","evidences":[{"source":"PubMed","id":"30926754","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32365187","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9D8S4","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---