6R9H
Crystal structure of the PDZ tandem of syntenin in complex with fragment C58
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0007268 | biological_process | chemical synaptic transmission |
| A | 0030036 | biological_process | actin cytoskeleton organization |
| A | 0035556 | biological_process | intracellular signal transduction |
| B | 0007268 | biological_process | chemical synaptic transmission |
| B | 0030036 | biological_process | actin cytoskeleton organization |
| B | 0035556 | biological_process | intracellular signal transduction |
| C | 0007268 | biological_process | chemical synaptic transmission |
| C | 0030036 | biological_process | actin cytoskeleton organization |
| C | 0035556 | biological_process | intracellular signal transduction |
| D | 0007268 | biological_process | chemical synaptic transmission |
| D | 0030036 | biological_process | actin cytoskeleton organization |
| D | 0035556 | biological_process | intracellular signal transduction |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 A 301 |
| Chain | Residue |
| A | HIS202 |
| A | SER226 |
| A | ARG229 |
| A | ASN230 |
| A | HOH421 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 A 302 |
| Chain | Residue |
| D | SER205 |
| A | ASN215 |
| A | LYS250 |
| A | ASP251 |
| A | HOH450 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | binding site for residue JVK A 303 |
| Chain | Residue |
| A | HIS208 |
| A | VAL209 |
| A | GLY210 |
| A | PHE211 |
| A | ILE212 |
| A | PHE213 |
| A | ASP251 |
| A | SER252 |
| A | ALA255 |
| A | LEU258 |
| A | HOH406 |
| D | SER259 |
| D | THR260 |
| D | SER261 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 304 |
| Chain | Residue |
| A | ILE125 |
| A | GLY126 |
| A | LEU127 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue ACT B 301 |
| Chain | Residue |
| B | HIS208 |
| B | VAL209 |
| B | GLY210 |
| B | PHE211 |
| B | HOH417 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 C 301 |
| Chain | Residue |
| C | HIS202 |
| C | SER226 |
| C | ARG229 |
| C | ASN230 |
| site_id | AC7 |
| Number of Residues | 17 |
| Details | binding site for residue JVK C 302 |
| Chain | Residue |
| B | SER259 |
| B | THR260 |
| B | SER261 |
| B | HOH423 |
| C | HIS208 |
| C | VAL209 |
| C | GLY210 |
| C | PHE211 |
| C | ILE212 |
| C | PHE213 |
| C | ASP251 |
| C | SER252 |
| C | ALA255 |
| C | LEU258 |
| C | HOH407 |
| C | HOH410 |
| C | HOH458 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 D 301 |
| Chain | Residue |
| D | HIS202 |
| D | SER226 |
| D | ARG229 |
| D | ASN230 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue ACT D 302 |
| Chain | Residue |
| D | HIS208 |
| D | VAL209 |
| D | GLY210 |
| D | PHE211 |
| D | HOH426 |
Functional Information from PROSITE/UniProt
| site_id | PS00070 |
| Number of Residues | 12 |
| Details | ALDEHYDE_DEHYDR_CYS Aldehyde dehydrogenases cysteine active site. LqINGENCAGWS |
| Chain | Residue | Details |
| A | LEU159-SER170 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 316 |
| Details | Domain: {"description":"PDZ 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00143","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27386966","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4Z33","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 150 |
| Details | Domain: {"description":"PDZ 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00143","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
