6R2U

Zinc-alpha2-Glycoprotein with a Fluorescent Dansyl C 11 Fatty Acid

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001580	biological_process	detection of chemical stimulus involved in sensory perception of bitter taste
A	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
A	0002476	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class Ib
A	0002486	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
A	0004540	molecular_function	RNA nuclease activity
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005634	cellular_component	nucleus
A	0006955	biological_process	immune response
A	0007155	biological_process	cell adhesion
A	0008285	biological_process	negative regulation of cell population proliferation
A	0008320	molecular_function	transmembrane protein transporter activity
A	0009897	cellular_component	external side of plasma membrane
A	0070062	cellular_component	extracellular exosome
A	0071806	biological_process	protein transmembrane transport
B	0001580	biological_process	detection of chemical stimulus involved in sensory perception of bitter taste
B	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
B	0002476	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class Ib
B	0002486	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
B	0004540	molecular_function	RNA nuclease activity
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005634	cellular_component	nucleus
B	0006955	biological_process	immune response
B	0007155	biological_process	cell adhesion
B	0008285	biological_process	negative regulation of cell population proliferation
B	0008320	molecular_function	transmembrane protein transporter activity
B	0009897	cellular_component	external side of plasma membrane
B	0070062	cellular_component	extracellular exosome
B	0071806	biological_process	protein transmembrane transport
C	0001580	biological_process	detection of chemical stimulus involved in sensory perception of bitter taste
C	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
C	0002476	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class Ib
C	0002486	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
C	0004540	molecular_function	RNA nuclease activity
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005634	cellular_component	nucleus
C	0006955	biological_process	immune response
C	0007155	biological_process	cell adhesion
C	0008285	biological_process	negative regulation of cell population proliferation
C	0008320	molecular_function	transmembrane protein transporter activity
C	0009897	cellular_component	external side of plasma membrane
C	0070062	cellular_component	extracellular exosome
C	0071806	biological_process	protein transmembrane transport
D	0001580	biological_process	detection of chemical stimulus involved in sensory perception of bitter taste
D	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
D	0002476	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class Ib
D	0002486	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
D	0004540	molecular_function	RNA nuclease activity
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005634	cellular_component	nucleus
D	0006955	biological_process	immune response
D	0007155	biological_process	cell adhesion
D	0008285	biological_process	negative regulation of cell population proliferation
D	0008320	molecular_function	transmembrane protein transporter activity
D	0009897	cellular_component	external side of plasma membrane
D	0070062	cellular_component	extracellular exosome
D	0071806	biological_process	protein transmembrane transport
E	0001580	biological_process	detection of chemical stimulus involved in sensory perception of bitter taste
E	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
E	0002476	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class Ib
E	0002486	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
E	0004540	molecular_function	RNA nuclease activity
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005634	cellular_component	nucleus
E	0006955	biological_process	immune response
E	0007155	biological_process	cell adhesion
E	0008285	biological_process	negative regulation of cell population proliferation
E	0008320	molecular_function	transmembrane protein transporter activity
E	0009897	cellular_component	external side of plasma membrane
E	0070062	cellular_component	extracellular exosome
E	0071806	biological_process	protein transmembrane transport
F	0001580	biological_process	detection of chemical stimulus involved in sensory perception of bitter taste
F	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
F	0002476	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class Ib
F	0002486	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
F	0004540	molecular_function	RNA nuclease activity
F	0005515	molecular_function	protein binding
F	0005576	cellular_component	extracellular region
F	0005634	cellular_component	nucleus
F	0006955	biological_process	immune response
F	0007155	biological_process	cell adhesion
F	0008285	biological_process	negative regulation of cell population proliferation
F	0008320	molecular_function	transmembrane protein transporter activity
F	0009897	cellular_component	external side of plasma membrane
F	0070062	cellular_component	extracellular exosome
F	0071806	biological_process	protein transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue SO4 A 301

Chain	Residue
A	ARG183
A	GLN184

---

site_id	AC2
Number of Residues	4
Details	binding site for residue SO4 A 302

Chain	Residue
A	GLU61
A	ASP62
A	TRP63
A	LYS64

---

site_id	AC3
Number of Residues	5
Details	binding site for residue SO4 A 303

Chain	Residue
F	PRO152
F	VAL153
A	ARG109
A	SER110
A	ARG171

---

site_id	AC4
Number of Residues	5
Details	binding site for residue SO4 A 304

Chain	Residue
A	HIS20
A	PRO25
A	ALA26
A	SER43
A	LYS44

---

site_id	AC5
Number of Residues	4
Details	binding site for residue 11D A 305

Chain	Residue
A	LYS204
A	LEU206
A	VAL234
A	GLN243

---

site_id	AC6
Number of Residues	13
Details	binding site for residue 11D B 301

Chain	Residue
B	ARG73
B	ILE76
B	PHE101
B	TRP115
B	TYR161
B	GLU165
B	CYS166
B	THR169
B	11D306
C	GLU151
C	TYR154
C	ARG157
C	11D301

---

site_id	AC7
Number of Residues	4
Details	binding site for residue AZI B 302

Chain	Residue
B	PHE114
B	TRP115
B	GLU126
B	PHE127

---

site_id	AC8
Number of Residues	5
Details	binding site for residue SO4 B 303

Chain	Residue
B	PRO25
B	ALA26
B	SER43
B	LYS44
B	HOH413

---

site_id	AC9
Number of Residues	4
Details	binding site for residue SO4 B 304

Chain	Residue
B	GLU61
B	ASP62
B	TRP63
B	LYS64

---

site_id	AD1
Number of Residues	6
Details	binding site for residue 11D B 305

Chain	Residue
B	THR192
B	LYS204
B	LEU206
B	VAL234
B	GLN243
B	TRP245

---

site_id	AD2
Number of Residues	17
Details	binding site for residue 11D B 306

Chain	Residue
B	LEU69
B	ARG73
B	ARG157
B	ALA160
B	TYR161
B	GLU164
B	GLU165
B	11D301
C	LEU69
C	ALA72
C	ARG73
C	TRP115
C	VAL153
C	TYR154
C	ARG157
C	TYR161
C	11D301

---

site_id	AD3
Number of Residues	10
Details	binding site for residue 11D C 301

Chain	Residue
B	TYR154
B	ARG157
B	TYR161
B	11D301
B	11D306
C	ARG73
C	TRP115
C	TYR117
C	TRP148
C	TYR154

---

site_id	AD4
Number of Residues	3
Details	binding site for residue SO4 C 302

Chain	Residue
C	SER110
C	GLY112
C	LYS129

---

site_id	AD5
Number of Residues	4
Details	binding site for residue SO4 C 303

Chain	Residue
C	ASN108
C	ARG109
C	SER110
C	ARG171

---

site_id	AD6
Number of Residues	5
Details	binding site for residue SO4 C 304

Chain	Residue
C	PRO25
C	ALA26
C	SER43
C	LYS44
C	HOH408

---

site_id	AD7
Number of Residues	7
Details	binding site for residue 11D D 301

Chain	Residue
A	GLN65
D	ARG73
D	ILE76
D	TRP115
D	TYR117
D	TRP148
D	TYR154

---

site_id	AD8
Number of Residues	4
Details	binding site for residue SO4 D 302

Chain	Residue
D	MET51
D	GLY52
D	ARG55
D	ARG40

---

site_id	AD9
Number of Residues	6
Details	binding site for residue SO4 D 303

Chain	Residue
D	VAL24
D	PRO25
D	ALA26
D	SER43
D	LYS44
D	HOH412

---

site_id	AE1
Number of Residues	4
Details	binding site for residue SO4 D 304

Chain	Residue
D	GLU61
D	ASP62
D	TRP63
D	LYS64

---

site_id	AE2
Number of Residues	5
Details	binding site for residue 11D E 301

Chain	Residue
E	ARG73
E	ILE76
E	TRP115
E	TYR117
E	TRP148

---

site_id	AE3
Number of Residues	5
Details	binding site for residue SO4 E 302

Chain	Residue
E	HIS20
E	VAL24
E	PRO25
E	ALA26
E	SER43

---

site_id	AE4
Number of Residues	6
Details	binding site for residue 11D F 301

Chain	Residue
F	ARG73
F	ILE76
F	PHE77
F	TRP115
F	TYR117
F	TRP148

---

site_id	AE5
Number of Residues	3
Details	binding site for residue SO4 F 302

Chain	Residue
F	ALA26
F	SER43
F	LYS44

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCHVQH

Chain	Residue	Details
A	TYR258-HIS264

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	510
Details	Domain: {"description":"Ig-like C1-type"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) (complex) asparagine","evidences":[{"source":"PubMed","id":"10206894","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16740002","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18780401","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19139490","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"14760718","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16740002","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18780401","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) (complex) asparagine","evidences":[{"source":"PubMed","id":"10206894","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14760718","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15084671","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15477100","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16740002","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18780401","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19139490","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22171320","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"10206894","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15477100","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18930737","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---