Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue HEC A 901 |
| Chain | Residue |
| A | CYS67 |
| A | CYS70 |
| A | HIS71 |
| A | HIS104 |
| A | GLN109 |
| A | HIS110 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue HEC A 902 |
| Chain | Residue |
| A | HIS104 |
| A | GLN124 |
| A | SER125 |
| A | GLN165 |
| A | VAL166 |
| A | HIS167 |
| A | HIS85 |
| A | CYS100 |
| A | CYS103 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue HEC A 903 |
| Chain | Residue |
| A | HIS85 |
| A | LYS92 |
| A | SER93 |
| A | CYS136 |
| A | CYS139 |
| A | HIS140 |
| A | HIS164 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue HEC A 904 |
| Chain | Residue |
| A | MET137 |
| A | HIS140 |
| A | LYS144 |
| A | ARG145 |
| A | TRP148 |
| A | HIS153 |
| A | CYS160 |
| A | CYS163 |
| A | HIS164 |
| A | LEU174 |
| A | SER210 |
| A | HIS216 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | binding site for residue HEC A 905 |
| Chain | Residue |
| A | HIS152 |
| A | HIS153 |
| A | ALA156 |
| A | VAL182 |
| A | CYS183 |
| A | SER185 |
| A | CYS186 |
| A | HIS187 |
| A | HIS213 |
| A | SER222 |
| B | ARG442 |
| B | LYS456 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | binding site for residue HEC A 906 |
| Chain | Residue |
| A | HIS187 |
| A | GLN190 |
| A | MET194 |
| A | HIS200 |
| A | CYS209 |
| A | CYS212 |
| A | HIS213 |
| A | SER222 |
| A | PRO261 |
| A | HIS262 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | binding site for residue HEC A 907 |
| Chain | Residue |
| A | HIS200 |
| A | ASP211 |
| A | THR232 |
| A | CYS233 |
| A | SER235 |
| A | CYS236 |
| A | HIS237 |
| A | HIS259 |
| A | ALA268 |
| A | HEC908 |
| B | ILE130 |
| B | THR132 |
| B | ARG181 |
| B | LYS207 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | binding site for residue HEC A 908 |
| Chain | Residue |
| A | HIS237 |
| A | LYS240 |
| A | VAL251 |
| A | CYS255 |
| A | CYS258 |
| A | HIS259 |
| A | ARG311 |
| A | HIS321 |
| A | HEC907 |
| B | LYS211 |
| site_id | AC9 |
| Number of Residues | 16 |
| Details | binding site for residue HEC A 909 |
| Chain | Residue |
| A | HIS248 |
| A | PRO250 |
| A | LEU277 |
| A | CYS278 |
| A | CYS281 |
| A | HIS282 |
| A | HIS317 |
| A | LYS329 |
| A | LEU330 |
| A | LEU331 |
| B | GLN429 |
| B | SER470 |
| B | THR473 |
| B | SER474 |
| B | LYS483 |
| B | ASN485 |
| site_id | AD1 |
| Number of Residues | 14 |
| Details | binding site for residue HEC A 910 |
| Chain | Residue |
| A | CYS316 |
| A | HIS317 |
| A | LEU330 |
| B | PHE218 |
| B | ASN219 |
| B | VAL379 |
| B | SER380 |
| B | ILE381 |
| B | SER475 |
| B | ASN671 |
| B | HOH803 |
| A | SER284 |
| A | HIS287 |
| A | CYS313 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue CA B 701 |
| Chain | Residue |
| B | ASN259 |
| B | ASN262 |
| B | ASP287 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 702 |
| Chain | Residue |
| B | ASP368 |
| B | ASN369 |
| B | ASP395 |
| B | HOH808 |
| B | HOH810 |
| site_id | AD4 |
| Number of Residues | 16 |
| Details | binding site for residue HEC C 801 |
| Chain | Residue |
| C | SER197 |
| C | CYS198 |
| C | CYS201 |
| C | HIS202 |
| C | VAL208 |
| C | LYS209 |
| C | HIS243 |
| C | LEU246 |
| C | LEU248 |
| C | SER250 |
| C | LEU251 |
| C | GLY560 |
| C | VAL561 |
| C | HEC802 |
| C | HEC802 |
| C | HOH906 |
| site_id | AD5 |
| Number of Residues | 14 |
| Details | binding site for residue HEC C 802 |
| Chain | Residue |
| C | TYR106 |
| C | LEU205 |
| C | LYS209 |
| C | HIS210 |
| C | TYR214 |
| C | TYR219 |
| C | CYS220 |
| C | CYS223 |
| C | HIS224 |
| C | VAL229 |
| C | GLY230 |
| C | LYS233 |
| C | HEC801 |
| C | HEC801 |
| site_id | AD6 |
| Number of Residues | 16 |
| Details | binding site for residue HEC C 803 |
| Chain | Residue |
| C | ALA101 |
| C | ARG190 |
| C | ILE192 |
| C | VAL193 |
| C | ALA221 |
| C | PHE235 |
| C | HIS240 |
| C | HIS243 |
| C | CYS254 |
| C | CYS257 |
| C | HIS258 |
| C | ASN269 |
| C | TRP270 |
| C | ILE273 |
| C | THR278 |
| C | HIS316 |
| site_id | AD7 |
| Number of Residues | 9 |
| Details | binding site for residue HEC C 804 |
| Chain | Residue |
| C | PRO274 |
| C | CYS279 |
| C | CYS282 |
| C | HIS283 |
| C | HIS307 |
| C | LEU315 |
| C | HIS316 |
| C | LYS319 |
| C | HEC805 |
| site_id | AD8 |
| Number of Residues | 14 |
| Details | binding site for residue HEC C 805 |
| Chain | Residue |
| B | PHE274 |
| B | ILE381 |
| C | THR275 |
| C | ALA276 |
| C | HIS283 |
| C | PHE288 |
| C | HIS294 |
| C | GLN297 |
| C | ASN300 |
| C | ASN302 |
| C | CYS303 |
| C | CYS306 |
| C | HIS307 |
| C | HEC804 |
| site_id | AD9 |
| Number of Residues | 12 |
| Details | binding site for residue HEC C 806 |
| Chain | Residue |
| C | CYS201 |
| C | THR247 |
| C | CYS488 |
| C | CYS491 |
| C | HIS492 |
| C | PHE496 |
| C | LEU552 |
| C | HIS556 |
| C | GLN559 |
| C | ILE562 |
| C | GLN567 |
| C | HEC807 |
| site_id | AE1 |
| Number of Residues | 13 |
| Details | binding site for residue HEC C 807 |
| Chain | Residue |
| C | GLU371 |
| C | VAL373 |
| C | PHE437 |
| C | HIS499 |
| C | CYS529 |
| C | CYS532 |
| C | HIS533 |
| C | THR538 |
| C | TYR539 |
| C | LYS551 |
| C | LEU552 |
| C | ILE555 |
| C | HEC806 |
| site_id | AE2 |
| Number of Residues | 12 |
| Details | binding site for residue HEC C 808 |
| Chain | Residue |
| C | ARG478 |
| C | HIS479 |
| C | SER482 |
| C | PHE548 |
| C | LEU552 |
| C | HIS553 |
| C | CYS565 |
| C | CYS568 |
| C | HIS569 |
| C | PHE572 |
| C | ASN573 |
| C | HIS645 |
| site_id | AE3 |
| Number of Residues | 7 |
| Details | binding site for residue HEC C 809 |
| Chain | Residue |
| C | CYS598 |
| C | CYS601 |
| C | HIS602 |
| C | HIS638 |
| C | HIS645 |
| C | THR646 |
| C | HEC810 |
| site_id | AE4 |
| Number of Residues | 11 |
| Details | binding site for residue HEC C 810 |
| Chain | Residue |
| C | THR595 |
| C | HIS602 |
| C | ILE607 |
| C | HIS609 |
| C | LEU611 |
| C | THR633 |
| C | CYS634 |
| C | CYS637 |
| C | HIS638 |
| C | MET650 |
| C | HEC809 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue CA C 811 |
| Chain | Residue |
| C | GLU464 |
| C | GLN511 |
| C | HOH903 |
| C | HOH905 |
| site_id | AE6 |
| Number of Residues | 7 |
| Details | binding site for residue CA C 812 |
| Chain | Residue |
| C | GLY537 |
| C | THR538 |
| C | GLY542 |
| C | ALA543 |
| C | ASN544 |
| C | LYS545 |
| C | GLY546 |
