Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016624 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor |
| A | 0030976 | molecular_function | thiamine pyrophosphate binding |
| B | 0016624 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor |
| B | 0030976 | molecular_function | thiamine pyrophosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 32 |
| Details | binding site for residue ZP1 A 2001 |
| Chain | Residue |
| A | HIS539 |
| A | ALA646 |
| A | ALA647 |
| A | GLN651 |
| A | ASN678 |
| A | ILE680 |
| A | GLY681 |
| A | PHE682 |
| A | HIS747 |
| A | MG2002 |
| A | HOH2140 |
| A | ARG540 |
| A | HOH2149 |
| A | HOH2220 |
| A | HOH2338 |
| A | HOH2376 |
| A | HOH2485 |
| A | HOH2493 |
| B | GLN901 |
| B | LEU950 |
| B | GLU952 |
| B | GLN976 |
| A | TYR578 |
| B | PHE977 |
| B | PHE980 |
| B | HIS1020 |
| A | HIS579 |
| A | SER604 |
| A | HIS605 |
| A | LEU606 |
| A | GLY644 |
| A | ASP645 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 2002 |
| Chain | Residue |
| A | ASP645 |
| A | ASN678 |
| A | ILE680 |
| A | ZP12001 |
| A | HOH2338 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 2003 |
| Chain | Residue |
| A | ASP1004 |
| A | HIS1055 |
| A | ASP1058 |
| A | ILE1060 |
| A | HOH2453 |
| A | HOH2657 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue MPD A 2004 |
| Chain | Residue |
| A | ARG771 |
| A | LYS772 |
| A | GLU776 |
| A | GLU790 |
| A | GLU873 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue MPD A 2005 |
| Chain | Residue |
| A | THR1183 |
| A | HOH2116 |
| A | HOH2148 |
| A | HOH2158 |
| B | ALA1172 |
| B | ASN1173 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue MPD A 2006 |
| Chain | Residue |
| A | GLU490 |
| A | THR494 |
| A | LEU793 |
| A | GLN797 |
| A | GLU873 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue MPD A 2007 |
| Chain | Residue |
| A | LYS480 |
| A | ALA792 |
| A | HOH2155 |
| site_id | AC8 |
| Number of Residues | 32 |
| Details | binding site for residue ZP1 B 2001 |
| Chain | Residue |
| A | GLN901 |
| A | LEU950 |
| A | GLU952 |
| A | GLN976 |
| A | PHE977 |
| A | PHE980 |
| A | HIS1020 |
| B | HIS539 |
| B | ARG540 |
| B | TYR578 |
| B | HIS579 |
| B | SER604 |
| B | HIS605 |
| B | LEU606 |
| B | GLY644 |
| B | ASP645 |
| B | ALA646 |
| B | ALA647 |
| B | GLN651 |
| B | ASN678 |
| B | ILE680 |
| B | GLY681 |
| B | PHE682 |
| B | HIS747 |
| B | MG2002 |
| B | HOH2118 |
| B | HOH2165 |
| B | HOH2173 |
| B | HOH2322 |
| B | HOH2325 |
| B | HOH2391 |
| B | HOH2399 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 2002 |
| Chain | Residue |
| B | ASP645 |
| B | ASN678 |
| B | ILE680 |
| B | ZP12001 |
| B | HOH2325 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 2003 |
| Chain | Residue |
| B | ASP1004 |
| B | HIS1055 |
| B | ASP1058 |
| B | ILE1060 |
| B | HOH2464 |
| B | HOH2553 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue MPD B 2004 |
| Chain | Residue |
| B | THR1086 |
| B | HOH2440 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue MPD B 2005 |
| Chain | Residue |
| B | LEU373 |
| B | ALA376 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 62 |
| Details | Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 30 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21867916","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2XTA","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21867916","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2Y0P","evidenceCode":"ECO:0007744"}]} |
