Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6QY3

Segment of the Cas1-Cas2-Csn2-DNA filament complex from the Type II-A CRISPR-Cas system

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0003677	molecular_function	DNA binding
a	0046872	molecular_function	metal ion binding
a	0051607	biological_process	defense response to virus
A	0003677	molecular_function	DNA binding
A	0046872	molecular_function	metal ion binding
A	0051607	biological_process	defense response to virus
b	0003677	molecular_function	DNA binding
b	0046872	molecular_function	metal ion binding
b	0051607	biological_process	defense response to virus
B	0003677	molecular_function	DNA binding
B	0046872	molecular_function	metal ion binding
B	0051607	biological_process	defense response to virus
c	0003677	molecular_function	DNA binding
c	0046872	molecular_function	metal ion binding
c	0051607	biological_process	defense response to virus
C	0003677	molecular_function	DNA binding
C	0046872	molecular_function	metal ion binding
C	0051607	biological_process	defense response to virus
d	0003677	molecular_function	DNA binding
d	0046872	molecular_function	metal ion binding
d	0051607	biological_process	defense response to virus
D	0003677	molecular_function	DNA binding
D	0046872	molecular_function	metal ion binding
D	0051607	biological_process	defense response to virus
e	0003677	molecular_function	DNA binding
e	0046872	molecular_function	metal ion binding
e	0051607	biological_process	defense response to virus
E	0003677	molecular_function	DNA binding
E	0046872	molecular_function	metal ion binding
E	0051607	biological_process	defense response to virus
f	0003677	molecular_function	DNA binding
f	0046872	molecular_function	metal ion binding
f	0051607	biological_process	defense response to virus
F	0003677	molecular_function	DNA binding
F	0046872	molecular_function	metal ion binding
F	0051607	biological_process	defense response to virus
g	0003677	molecular_function	DNA binding
g	0046872	molecular_function	metal ion binding
g	0051607	biological_process	defense response to virus
G	0003677	molecular_function	DNA binding
G	0046872	molecular_function	metal ion binding
G	0051607	biological_process	defense response to virus
h	0003677	molecular_function	DNA binding
h	0046872	molecular_function	metal ion binding
h	0051607	biological_process	defense response to virus
H	0003677	molecular_function	DNA binding
H	0046872	molecular_function	metal ion binding
H	0051607	biological_process	defense response to virus
i	0003676	molecular_function	nucleic acid binding
i	0003677	molecular_function	DNA binding
i	0004519	molecular_function	endonuclease activity
i	0004520	molecular_function	DNA endonuclease activity
i	0043571	biological_process	maintenance of CRISPR repeat elements
i	0046872	molecular_function	metal ion binding
i	0051607	biological_process	defense response to virus
I	0003676	molecular_function	nucleic acid binding
I	0003677	molecular_function	DNA binding
I	0004519	molecular_function	endonuclease activity
I	0004520	molecular_function	DNA endonuclease activity
I	0043571	biological_process	maintenance of CRISPR repeat elements
I	0046872	molecular_function	metal ion binding
I	0051607	biological_process	defense response to virus
j	0003676	molecular_function	nucleic acid binding
j	0003677	molecular_function	DNA binding
j	0004519	molecular_function	endonuclease activity
j	0004520	molecular_function	DNA endonuclease activity
j	0043571	biological_process	maintenance of CRISPR repeat elements
j	0046872	molecular_function	metal ion binding
j	0051607	biological_process	defense response to virus
J	0003676	molecular_function	nucleic acid binding
J	0003677	molecular_function	DNA binding
J	0004519	molecular_function	endonuclease activity
J	0004520	molecular_function	DNA endonuclease activity
J	0043571	biological_process	maintenance of CRISPR repeat elements
J	0046872	molecular_function	metal ion binding
J	0051607	biological_process	defense response to virus
k	0004519	molecular_function	endonuclease activity
k	0004521	molecular_function	RNA endonuclease activity
k	0043571	biological_process	maintenance of CRISPR repeat elements
k	0046872	molecular_function	metal ion binding
k	0051607	biological_process	defense response to virus
K	0004519	molecular_function	endonuclease activity
K	0004521	molecular_function	RNA endonuclease activity
K	0043571	biological_process	maintenance of CRISPR repeat elements
K	0046872	molecular_function	metal ion binding
K	0051607	biological_process	defense response to virus
l	0003676	molecular_function	nucleic acid binding
l	0003677	molecular_function	DNA binding
l	0004519	molecular_function	endonuclease activity
l	0004520	molecular_function	DNA endonuclease activity
l	0043571	biological_process	maintenance of CRISPR repeat elements
l	0046872	molecular_function	metal ion binding
l	0051607	biological_process	defense response to virus
L	0003676	molecular_function	nucleic acid binding
L	0003677	molecular_function	DNA binding
L	0004519	molecular_function	endonuclease activity
L	0004520	molecular_function	DNA endonuclease activity
L	0043571	biological_process	maintenance of CRISPR repeat elements
L	0046872	molecular_function	metal ion binding
L	0051607	biological_process	defense response to virus
m	0003676	molecular_function	nucleic acid binding
m	0003677	molecular_function	DNA binding
m	0004519	molecular_function	endonuclease activity
m	0004520	molecular_function	DNA endonuclease activity
m	0043571	biological_process	maintenance of CRISPR repeat elements
m	0046872	molecular_function	metal ion binding
m	0051607	biological_process	defense response to virus
M	0003676	molecular_function	nucleic acid binding
M	0003677	molecular_function	DNA binding
M	0004519	molecular_function	endonuclease activity
M	0004520	molecular_function	DNA endonuclease activity
M	0043571	biological_process	maintenance of CRISPR repeat elements
M	0046872	molecular_function	metal ion binding
M	0051607	biological_process	defense response to virus
n	0004519	molecular_function	endonuclease activity
n	0004521	molecular_function	RNA endonuclease activity
n	0043571	biological_process	maintenance of CRISPR repeat elements
n	0046872	molecular_function	metal ion binding
n	0051607	biological_process	defense response to virus
N	0004519	molecular_function	endonuclease activity
N	0004521	molecular_function	RNA endonuclease activity
N	0043571	biological_process	maintenance of CRISPR repeat elements
N	0046872	molecular_function	metal ion binding
N	0051607	biological_process	defense response to virus
o	0003676	molecular_function	nucleic acid binding
o	0003677	molecular_function	DNA binding
o	0004519	molecular_function	endonuclease activity
o	0004520	molecular_function	DNA endonuclease activity
o	0043571	biological_process	maintenance of CRISPR repeat elements
o	0046872	molecular_function	metal ion binding
o	0051607	biological_process	defense response to virus
O	0003676	molecular_function	nucleic acid binding
O	0003677	molecular_function	DNA binding
O	0004519	molecular_function	endonuclease activity
O	0004520	molecular_function	DNA endonuclease activity
O	0043571	biological_process	maintenance of CRISPR repeat elements
O	0046872	molecular_function	metal ion binding
O	0051607	biological_process	defense response to virus
p	0003676	molecular_function	nucleic acid binding
p	0003677	molecular_function	DNA binding
p	0004519	molecular_function	endonuclease activity
p	0004520	molecular_function	DNA endonuclease activity
p	0043571	biological_process	maintenance of CRISPR repeat elements
p	0046872	molecular_function	metal ion binding
p	0051607	biological_process	defense response to virus
P	0003676	molecular_function	nucleic acid binding
P	0003677	molecular_function	DNA binding
P	0004519	molecular_function	endonuclease activity
P	0004520	molecular_function	DNA endonuclease activity
P	0043571	biological_process	maintenance of CRISPR repeat elements
P	0046872	molecular_function	metal ion binding
P	0051607	biological_process	defense response to virus
q	0004519	molecular_function	endonuclease activity
q	0004521	molecular_function	RNA endonuclease activity
q	0043571	biological_process	maintenance of CRISPR repeat elements
q	0046872	molecular_function	metal ion binding
q	0051607	biological_process	defense response to virus
Q	0004519	molecular_function	endonuclease activity
Q	0004521	molecular_function	RNA endonuclease activity
Q	0043571	biological_process	maintenance of CRISPR repeat elements
Q	0046872	molecular_function	metal ion binding
Q	0051607	biological_process	defense response to virus
r	0003676	molecular_function	nucleic acid binding
r	0003677	molecular_function	DNA binding
r	0004519	molecular_function	endonuclease activity
r	0004520	molecular_function	DNA endonuclease activity
r	0043571	biological_process	maintenance of CRISPR repeat elements
r	0046872	molecular_function	metal ion binding
r	0051607	biological_process	defense response to virus
R	0003676	molecular_function	nucleic acid binding
R	0003677	molecular_function	DNA binding
R	0004519	molecular_function	endonuclease activity
R	0004520	molecular_function	DNA endonuclease activity
R	0043571	biological_process	maintenance of CRISPR repeat elements
R	0046872	molecular_function	metal ion binding
R	0051607	biological_process	defense response to virus
s	0003676	molecular_function	nucleic acid binding
s	0003677	molecular_function	DNA binding
s	0004519	molecular_function	endonuclease activity
s	0004520	molecular_function	DNA endonuclease activity
s	0043571	biological_process	maintenance of CRISPR repeat elements
s	0046872	molecular_function	metal ion binding
s	0051607	biological_process	defense response to virus
S	0003676	molecular_function	nucleic acid binding
S	0003677	molecular_function	DNA binding
S	0004519	molecular_function	endonuclease activity
S	0004520	molecular_function	DNA endonuclease activity
S	0043571	biological_process	maintenance of CRISPR repeat elements
S	0046872	molecular_function	metal ion binding
S	0051607	biological_process	defense response to virus
t	0004519	molecular_function	endonuclease activity
t	0004521	molecular_function	RNA endonuclease activity
t	0043571	biological_process	maintenance of CRISPR repeat elements
t	0046872	molecular_function	metal ion binding
t	0051607	biological_process	defense response to virus
T	0004519	molecular_function	endonuclease activity
T	0004521	molecular_function	RNA endonuclease activity
T	0043571	biological_process	maintenance of CRISPR repeat elements
T	0046872	molecular_function	metal ion binding
T	0051607	biological_process	defense response to virus
u	0003676	molecular_function	nucleic acid binding
u	0003677	molecular_function	DNA binding
u	0004519	molecular_function	endonuclease activity
u	0004520	molecular_function	DNA endonuclease activity
u	0043571	biological_process	maintenance of CRISPR repeat elements
u	0046872	molecular_function	metal ion binding
u	0051607	biological_process	defense response to virus
U	0003676	molecular_function	nucleic acid binding
U	0003677	molecular_function	DNA binding
U	0004519	molecular_function	endonuclease activity
U	0004520	molecular_function	DNA endonuclease activity
U	0043571	biological_process	maintenance of CRISPR repeat elements
U	0046872	molecular_function	metal ion binding
U	0051607	biological_process	defense response to virus
v	0003676	molecular_function	nucleic acid binding
v	0003677	molecular_function	DNA binding
v	0004519	molecular_function	endonuclease activity
v	0004520	molecular_function	DNA endonuclease activity
v	0043571	biological_process	maintenance of CRISPR repeat elements
v	0046872	molecular_function	metal ion binding
v	0051607	biological_process	defense response to virus
V	0003676	molecular_function	nucleic acid binding
V	0003677	molecular_function	DNA binding
V	0004519	molecular_function	endonuclease activity
V	0004520	molecular_function	DNA endonuclease activity
V	0043571	biological_process	maintenance of CRISPR repeat elements
V	0046872	molecular_function	metal ion binding
V	0051607	biological_process	defense response to virus
w	0004519	molecular_function	endonuclease activity
w	0004521	molecular_function	RNA endonuclease activity
w	0043571	biological_process	maintenance of CRISPR repeat elements
w	0046872	molecular_function	metal ion binding
w	0051607	biological_process	defense response to virus
W	0004519	molecular_function	endonuclease activity
W	0004521	molecular_function	RNA endonuclease activity
W	0043571	biological_process	maintenance of CRISPR repeat elements
W	0046872	molecular_function	metal ion binding
W	0051607	biological_process	defense response to virus
x	0004519	molecular_function	endonuclease activity
x	0004521	molecular_function	RNA endonuclease activity
x	0043571	biological_process	maintenance of CRISPR repeat elements
x	0046872	molecular_function	metal ion binding
x	0051607	biological_process	defense response to virus
X	0004519	molecular_function	endonuclease activity
X	0004521	molecular_function	RNA endonuclease activity
X	0043571	biological_process	maintenance of CRISPR repeat elements
X	0046872	molecular_function	metal ion binding
X	0051607	biological_process	defense response to virus
y	0003676	molecular_function	nucleic acid binding
y	0003677	molecular_function	DNA binding
y	0004519	molecular_function	endonuclease activity
y	0004520	molecular_function	DNA endonuclease activity
y	0043571	biological_process	maintenance of CRISPR repeat elements
y	0046872	molecular_function	metal ion binding
y	0051607	biological_process	defense response to virus
Y	0003676	molecular_function	nucleic acid binding
Y	0003677	molecular_function	DNA binding
Y	0004519	molecular_function	endonuclease activity
Y	0004520	molecular_function	DNA endonuclease activity
Y	0043571	biological_process	maintenance of CRISPR repeat elements
Y	0046872	molecular_function	metal ion binding
Y	0051607	biological_process	defense response to virus
z	0003676	molecular_function	nucleic acid binding
z	0003677	molecular_function	DNA binding
z	0004519	molecular_function	endonuclease activity
z	0004520	molecular_function	DNA endonuclease activity
z	0043571	biological_process	maintenance of CRISPR repeat elements
z	0046872	molecular_function	metal ion binding
z	0051607	biological_process	defense response to virus
Z	0003676	molecular_function	nucleic acid binding
Z	0003677	molecular_function	DNA binding
Z	0004519	molecular_function	endonuclease activity
Z	0004520	molecular_function	DNA endonuclease activity
Z	0043571	biological_process	maintenance of CRISPR repeat elements
Z	0046872	molecular_function	metal ion binding
Z	0051607	biological_process	defense response to virus

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue CA A 501

Chain	Residue
A	GLU123
D	ALA132

site_id	AC2
Number of Residues	2
Details	binding site for residue CA A 502

Chain	Residue
A	ALA132
D	GLU123

site_id	AC3
Number of Residues	2
Details	binding site for residue CA B 501

Chain	Residue
B	GLU123
C	ALA132

site_id	AC4
Number of Residues	2
Details	binding site for residue CA B 502

Chain	Residue
B	ALA132
C	GLU123

site_id	AC5
Number of Residues	2
Details	binding site for residue CA E 501

Chain	Residue
H	ALA132
E	GLU123

site_id	AC6
Number of Residues	2
Details	binding site for residue CA E 502

Chain	Residue
E	ALA132
H	GLU123

site_id	AC7
Number of Residues	2
Details	binding site for residue CA F 501

Chain	Residue
F	GLU123
G	ALA132

site_id	AC8
Number of Residues	2
Details	binding site for residue CA F 502

Chain	Residue
F	ALA132
G	GLU123

site_id	AC9
Number of Residues	2
Details	binding site for residue CA a 501

Chain	Residue
a	GLU123
d	ALA132

site_id	AD1
Number of Residues	2
Details	binding site for residue CA a 502

Chain	Residue
a	ALA132
d	GLU123

site_id	AD2
Number of Residues	2
Details	binding site for residue CA b 501

Chain	Residue
b	ASP122
b	GLU123

site_id	AD3
Number of Residues	2
Details	binding site for residue CA b 502

Chain	Residue
b	ALA132
c	GLU123

site_id	AD4
Number of Residues	2
Details	binding site for residue CA e 501

Chain	Residue
e	GLU123
h	ALA132

site_id	AD5
Number of Residues	2
Details	binding site for residue CA e 502

Chain	Residue
e	ALA132
h	GLU123

site_id	AD6
Number of Residues	2
Details	binding site for residue CA f 501

Chain	Residue
f	GLU123
g	ALA132

site_id	AD7
Number of Residues	2
Details	binding site for residue CA f 502

Chain	Residue
f	ALA132
g	GLU123

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
K	ASP13
t	ASP13
w	ASP13
x	ASP13
O	GLU149
O	HIS205
O	GLU220
P	GLU149
P	HIS205
P	GLU220
R	GLU149
N	ASP13
R	HIS205
R	GLU220
S	GLU149
S	HIS205
S	GLU220
U	GLU149
U	HIS205
U	GLU220
V	GLU149
V	HIS205
Q	ASP13
V	GLU220
Y	GLU149
Y	HIS205
Y	GLU220
Z	GLU149
Z	HIS205
Z	GLU220
i	GLU149
i	HIS205
i	GLU220
T	ASP13
j	GLU149
j	HIS205
j	GLU220
l	GLU149
l	HIS205
l	GLU220
m	GLU149
m	HIS205
m	GLU220
o	GLU149
W	ASP13
o	HIS205
o	GLU220
p	GLU149
p	HIS205
p	GLU220
r	GLU149
r	HIS205
r	GLU220
s	GLU149
s	HIS205
X	ASP13
s	GLU220
u	GLU149
u	HIS205
u	GLU220
v	GLU149
v	HIS205
v	GLU220
y	GLU149
y	HIS205
y	GLU220
k	ASP13
z	GLU149
z	HIS205
z	GLU220
n	ASP13
q	ASP13

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)