Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6QXF

Cas1-Cas2-Csn2-DNA complex from the Type II-A CRISPR-Cas system

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0046872	molecular_function	metal ion binding
A	0051607	biological_process	defense response to virus
B	0003677	molecular_function	DNA binding
B	0046872	molecular_function	metal ion binding
B	0051607	biological_process	defense response to virus
C	0003677	molecular_function	DNA binding
C	0046872	molecular_function	metal ion binding
C	0051607	biological_process	defense response to virus
D	0003677	molecular_function	DNA binding
D	0046872	molecular_function	metal ion binding
D	0051607	biological_process	defense response to virus
E	0003677	molecular_function	DNA binding
E	0046872	molecular_function	metal ion binding
E	0051607	biological_process	defense response to virus
F	0003677	molecular_function	DNA binding
F	0046872	molecular_function	metal ion binding
F	0051607	biological_process	defense response to virus
G	0003677	molecular_function	DNA binding
G	0046872	molecular_function	metal ion binding
G	0051607	biological_process	defense response to virus
H	0003677	molecular_function	DNA binding
H	0046872	molecular_function	metal ion binding
H	0051607	biological_process	defense response to virus
I	0003676	molecular_function	nucleic acid binding
I	0003677	molecular_function	DNA binding
I	0004519	molecular_function	endonuclease activity
I	0004520	molecular_function	DNA endonuclease activity
I	0043571	biological_process	maintenance of CRISPR repeat elements
I	0046872	molecular_function	metal ion binding
I	0051607	biological_process	defense response to virus
J	0003676	molecular_function	nucleic acid binding
J	0003677	molecular_function	DNA binding
J	0004519	molecular_function	endonuclease activity
J	0004520	molecular_function	DNA endonuclease activity
J	0043571	biological_process	maintenance of CRISPR repeat elements
J	0046872	molecular_function	metal ion binding
J	0051607	biological_process	defense response to virus
K	0004519	molecular_function	endonuclease activity
K	0004521	molecular_function	RNA endonuclease activity
K	0043571	biological_process	maintenance of CRISPR repeat elements
K	0046872	molecular_function	metal ion binding
K	0051607	biological_process	defense response to virus
L	0003676	molecular_function	nucleic acid binding
L	0003677	molecular_function	DNA binding
L	0004519	molecular_function	endonuclease activity
L	0004520	molecular_function	DNA endonuclease activity
L	0043571	biological_process	maintenance of CRISPR repeat elements
L	0046872	molecular_function	metal ion binding
L	0051607	biological_process	defense response to virus
M	0003676	molecular_function	nucleic acid binding
M	0003677	molecular_function	DNA binding
M	0004519	molecular_function	endonuclease activity
M	0004520	molecular_function	DNA endonuclease activity
M	0043571	biological_process	maintenance of CRISPR repeat elements
M	0046872	molecular_function	metal ion binding
M	0051607	biological_process	defense response to virus
N	0004519	molecular_function	endonuclease activity
N	0004521	molecular_function	RNA endonuclease activity
N	0043571	biological_process	maintenance of CRISPR repeat elements
N	0046872	molecular_function	metal ion binding
N	0051607	biological_process	defense response to virus
O	0003676	molecular_function	nucleic acid binding
O	0003677	molecular_function	DNA binding
O	0004519	molecular_function	endonuclease activity
O	0004520	molecular_function	DNA endonuclease activity
O	0043571	biological_process	maintenance of CRISPR repeat elements
O	0046872	molecular_function	metal ion binding
O	0051607	biological_process	defense response to virus
P	0003676	molecular_function	nucleic acid binding
P	0003677	molecular_function	DNA binding
P	0004519	molecular_function	endonuclease activity
P	0004520	molecular_function	DNA endonuclease activity
P	0043571	biological_process	maintenance of CRISPR repeat elements
P	0046872	molecular_function	metal ion binding
P	0051607	biological_process	defense response to virus
Q	0004519	molecular_function	endonuclease activity
Q	0004521	molecular_function	RNA endonuclease activity
Q	0043571	biological_process	maintenance of CRISPR repeat elements
Q	0046872	molecular_function	metal ion binding
Q	0051607	biological_process	defense response to virus
R	0003676	molecular_function	nucleic acid binding
R	0003677	molecular_function	DNA binding
R	0004519	molecular_function	endonuclease activity
R	0004520	molecular_function	DNA endonuclease activity
R	0043571	biological_process	maintenance of CRISPR repeat elements
R	0046872	molecular_function	metal ion binding
R	0051607	biological_process	defense response to virus
S	0003676	molecular_function	nucleic acid binding
S	0003677	molecular_function	DNA binding
S	0004519	molecular_function	endonuclease activity
S	0004520	molecular_function	DNA endonuclease activity
S	0043571	biological_process	maintenance of CRISPR repeat elements
S	0046872	molecular_function	metal ion binding
S	0051607	biological_process	defense response to virus
T	0004519	molecular_function	endonuclease activity
T	0004521	molecular_function	RNA endonuclease activity
T	0043571	biological_process	maintenance of CRISPR repeat elements
T	0046872	molecular_function	metal ion binding
T	0051607	biological_process	defense response to virus

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue CA A 501

Chain	Residue
A	ASP122
A	GLU123
A	GLU128
D	ALA132

site_id	AC2
Number of Residues	4
Details	binding site for residue CA B 501

Chain	Residue
B	ASP122
B	GLU123
B	GLU128
C	ALA132

site_id	AC3
Number of Residues	4
Details	binding site for residue CA C 501

Chain	Residue
C	ASP122
C	GLU123
C	GLU128
B	ALA132

site_id	AC4
Number of Residues	4
Details	binding site for residue CA D 501

Chain	Residue
A	ALA132
D	ASP122
D	GLU123
D	GLU128

site_id	AC5
Number of Residues	4
Details	binding site for residue CA E 501

Chain	Residue
E	ASP122
E	GLU123
E	GLU128
H	ALA132

site_id	AC6
Number of Residues	4
Details	binding site for residue CA F 501

Chain	Residue
F	ASP122
F	GLU123
F	GLU128
G	ALA132

site_id	AC7
Number of Residues	4
Details	binding site for residue CA G 501

Chain	Residue
F	ALA132
G	ASP122
G	GLU123
G	GLU128

site_id	AC8
Number of Residues	4
Details	binding site for residue CA H 501

Chain	Residue
E	ALA132
H	ASP122
H	GLU123
H	GLU128

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
K	ASP13
M	GLU149
M	HIS205
M	GLU220
O	GLU149
O	HIS205
O	GLU220
P	GLU149
P	HIS205
P	GLU220
R	GLU149
N	ASP13
R	HIS205
R	GLU220
S	GLU149
S	HIS205
S	GLU220
Q	ASP13
T	ASP13
J	HIS205
J	GLU220
L	GLU149
L	HIS205
L	GLU220

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)