Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 401 |
| Chain | Residue |
| A | LYS46 |
| A | ARG48 |
| A | LYS86 |
| A | GLU224 |
| A | ASN228 |
| A | ASN233 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | ILE188 |
| A | TYR191 |
| A | ILE177 |
| A | PHE178 |
| A | GLY179 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 403 |
| Chain | Residue |
| A | ASN75 |
| A | GLN122 |
| A | ASN125 |
| A | HOH511 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 404 |
| Chain | Residue |
| A | GLN38 |
| A | TYR39 |
| A | GLU94 |
| A | LEU95 |
| A | SER132 |
| A | HOH506 |
| A | HOH530 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 405 |
| Chain | Residue |
| A | ALA40 |
| A | ILE77 |
| A | GLU94 |
| A | LEU95 |
| A | VAL96 |
| A | ILE160 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 406 |
| Chain | Residue |
| A | ARG5 |
| A | TYR12 |
| A | GLU32 |
| A | SER34 |
| A | GLN271 |
| A | HOH558 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 407 |
| Chain | Residue |
| A | LYS42 |
| A | GLU64 |
| A | HOH522 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 408 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 409 |
| Chain | Residue |
| A | GLU235 |
| A | ARG253 |
| site_id | AD1 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 410 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 411 |
| Chain | Residue |
| A | GLU100 |
| A | ASP103 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue PGE A 412 |
| Chain | Residue |
| A | HIS80 |
| A | HIS131 |
| A | SER132 |
| A | GLN134 |
| A | LEU196 |
| A | ILE266 |
| A | GLN267 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 28 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGSGQFAVVKkCrekstglqyaak......FIKK |
| Chain | Residue | Details |
| A | LEU19-LYS46 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IaHfDLKpeNIML |
| Chain | Residue | Details |
| A | ILE135-LEU147 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 262 |
| Details | Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | Region: {"description":"Autoinhibitory domain","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 13 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by RPS6KA1 and RPS6KA3","evidences":[{"source":"PubMed","id":"16213824","evidenceCode":"ECO:0000269"}]} |
