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6QL7

Structure of fatty acid synthase complex with bound gamma subunit from Saccharomyces cerevisiae at 4.6 angstrom

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
A0000287molecular_functionmagnesium ion binding
A0003824molecular_functioncatalytic activity
A0004312molecular_functionfatty acid synthase activity
A0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
A0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
A0004321molecular_functionfatty-acyl-CoA synthase activity
A0005515molecular_functionprotein binding
A0005739cellular_componentmitochondrion
A0005829cellular_componentcytosol
A0005835cellular_componentfatty acid synthase complex
A0006629biological_processlipid metabolic process
A0006631biological_processfatty acid metabolic process
A0006633biological_processfatty acid biosynthetic process
A0008897molecular_functionholo-[acyl-carrier-protein] synthase activity
A0016491molecular_functionoxidoreductase activity
A0016740molecular_functiontransferase activity
A0016746molecular_functionacyltransferase activity
A0042759biological_processlong-chain fatty acid biosynthetic process
A0046872molecular_functionmetal ion binding
B0000287molecular_functionmagnesium ion binding
B0003824molecular_functioncatalytic activity
B0004312molecular_functionfatty acid synthase activity
B0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
B0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
B0004321molecular_functionfatty-acyl-CoA synthase activity
B0005515molecular_functionprotein binding
B0005739cellular_componentmitochondrion
B0005829cellular_componentcytosol
B0005835cellular_componentfatty acid synthase complex
B0006629biological_processlipid metabolic process
B0006631biological_processfatty acid metabolic process
B0006633biological_processfatty acid biosynthetic process
B0008897molecular_functionholo-[acyl-carrier-protein] synthase activity
B0016491molecular_functionoxidoreductase activity
B0016740molecular_functiontransferase activity
B0016746molecular_functionacyltransferase activity
B0042759biological_processlong-chain fatty acid biosynthetic process
B0046872molecular_functionmetal ion binding
C0000287molecular_functionmagnesium ion binding
C0003824molecular_functioncatalytic activity
C0004312molecular_functionfatty acid synthase activity
C0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
C0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
C0004321molecular_functionfatty-acyl-CoA synthase activity
C0005515molecular_functionprotein binding
C0005739cellular_componentmitochondrion
C0005829cellular_componentcytosol
C0005835cellular_componentfatty acid synthase complex
C0006629biological_processlipid metabolic process
C0006631biological_processfatty acid metabolic process
C0006633biological_processfatty acid biosynthetic process
C0008897molecular_functionholo-[acyl-carrier-protein] synthase activity
C0016491molecular_functionoxidoreductase activity
C0016740molecular_functiontransferase activity
C0016746molecular_functionacyltransferase activity
C0042759biological_processlong-chain fatty acid biosynthetic process
C0046872molecular_functionmetal ion binding
D0000287molecular_functionmagnesium ion binding
D0003824molecular_functioncatalytic activity
D0004312molecular_functionfatty acid synthase activity
D0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
D0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
D0004321molecular_functionfatty-acyl-CoA synthase activity
D0005515molecular_functionprotein binding
D0005739cellular_componentmitochondrion
D0005829cellular_componentcytosol
D0005835cellular_componentfatty acid synthase complex
D0006629biological_processlipid metabolic process
D0006631biological_processfatty acid metabolic process
D0006633biological_processfatty acid biosynthetic process
D0008897molecular_functionholo-[acyl-carrier-protein] synthase activity
D0016491molecular_functionoxidoreductase activity
D0016740molecular_functiontransferase activity
D0016746molecular_functionacyltransferase activity
D0042759biological_processlong-chain fatty acid biosynthetic process
D0046872molecular_functionmetal ion binding
E0000287molecular_functionmagnesium ion binding
E0003824molecular_functioncatalytic activity
E0004312molecular_functionfatty acid synthase activity
E0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
E0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
E0004321molecular_functionfatty-acyl-CoA synthase activity
E0005515molecular_functionprotein binding
E0005739cellular_componentmitochondrion
E0005829cellular_componentcytosol
E0005835cellular_componentfatty acid synthase complex
E0006629biological_processlipid metabolic process
E0006631biological_processfatty acid metabolic process
E0006633biological_processfatty acid biosynthetic process
E0008897molecular_functionholo-[acyl-carrier-protein] synthase activity
E0016491molecular_functionoxidoreductase activity
E0016740molecular_functiontransferase activity
E0016746molecular_functionacyltransferase activity
E0042759biological_processlong-chain fatty acid biosynthetic process
E0046872molecular_functionmetal ion binding
F0000287molecular_functionmagnesium ion binding
F0003824molecular_functioncatalytic activity
F0004312molecular_functionfatty acid synthase activity
F0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
F0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
F0004321molecular_functionfatty-acyl-CoA synthase activity
F0005515molecular_functionprotein binding
F0005739cellular_componentmitochondrion
F0005829cellular_componentcytosol
F0005835cellular_componentfatty acid synthase complex
F0006629biological_processlipid metabolic process
F0006631biological_processfatty acid metabolic process
F0006633biological_processfatty acid biosynthetic process
F0008897molecular_functionholo-[acyl-carrier-protein] synthase activity
F0016491molecular_functionoxidoreductase activity
F0016740molecular_functiontransferase activity
F0016746molecular_functionacyltransferase activity
F0042759biological_processlong-chain fatty acid biosynthetic process
F0046872molecular_functionmetal ion binding
G0003824molecular_functioncatalytic activity
G0004312molecular_functionfatty acid synthase activity
G0004313molecular_function[acyl-carrier-protein] S-acetyltransferase activity
G0004314molecular_function[acyl-carrier-protein] S-malonyltransferase activity
G0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
G0004321molecular_functionfatty-acyl-CoA synthase activity
G0005515molecular_functionprotein binding
G0005737cellular_componentcytoplasm
G0005739cellular_componentmitochondrion
G0005811cellular_componentlipid droplet
G0005829cellular_componentcytosol
G0005835cellular_componentfatty acid synthase complex
G0006629biological_processlipid metabolic process
G0006631biological_processfatty acid metabolic process
G0006633biological_processfatty acid biosynthetic process
G0016297molecular_functionfatty acyl-[ACP] hydrolase activity
G0016409molecular_functionpalmitoyltransferase activity
G0016491molecular_functionoxidoreductase activity
G0016740molecular_functiontransferase activity
G0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
G0016787molecular_functionhydrolase activity
G0016829molecular_functionlyase activity
G0019171molecular_function(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
G0042759biological_processlong-chain fatty acid biosynthetic process
G0141148molecular_functionenoyl-[acyl-carrier-protein] reductase (NADPH) activity
H0003824molecular_functioncatalytic activity
H0004312molecular_functionfatty acid synthase activity
H0004313molecular_function[acyl-carrier-protein] S-acetyltransferase activity
H0004314molecular_function[acyl-carrier-protein] S-malonyltransferase activity
H0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
H0004321molecular_functionfatty-acyl-CoA synthase activity
H0005515molecular_functionprotein binding
H0005737cellular_componentcytoplasm
H0005739cellular_componentmitochondrion
H0005811cellular_componentlipid droplet
H0005829cellular_componentcytosol
H0005835cellular_componentfatty acid synthase complex
H0006629biological_processlipid metabolic process
H0006631biological_processfatty acid metabolic process
H0006633biological_processfatty acid biosynthetic process
H0016297molecular_functionfatty acyl-[ACP] hydrolase activity
H0016409molecular_functionpalmitoyltransferase activity
H0016491molecular_functionoxidoreductase activity
H0016740molecular_functiontransferase activity
H0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
H0016787molecular_functionhydrolase activity
H0016829molecular_functionlyase activity
H0019171molecular_function(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
H0042759biological_processlong-chain fatty acid biosynthetic process
H0141148molecular_functionenoyl-[acyl-carrier-protein] reductase (NADPH) activity
I0003824molecular_functioncatalytic activity
I0004312molecular_functionfatty acid synthase activity
I0004313molecular_function[acyl-carrier-protein] S-acetyltransferase activity
I0004314molecular_function[acyl-carrier-protein] S-malonyltransferase activity
I0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
I0004321molecular_functionfatty-acyl-CoA synthase activity
I0005515molecular_functionprotein binding
I0005737cellular_componentcytoplasm
I0005739cellular_componentmitochondrion
I0005811cellular_componentlipid droplet
I0005829cellular_componentcytosol
I0005835cellular_componentfatty acid synthase complex
I0006629biological_processlipid metabolic process
I0006631biological_processfatty acid metabolic process
I0006633biological_processfatty acid biosynthetic process
I0016297molecular_functionfatty acyl-[ACP] hydrolase activity
I0016409molecular_functionpalmitoyltransferase activity
I0016491molecular_functionoxidoreductase activity
I0016740molecular_functiontransferase activity
I0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
I0016787molecular_functionhydrolase activity
I0016829molecular_functionlyase activity
I0019171molecular_function(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
I0042759biological_processlong-chain fatty acid biosynthetic process
I0141148molecular_functionenoyl-[acyl-carrier-protein] reductase (NADPH) activity
J0003824molecular_functioncatalytic activity
J0004312molecular_functionfatty acid synthase activity
J0004313molecular_function[acyl-carrier-protein] S-acetyltransferase activity
J0004314molecular_function[acyl-carrier-protein] S-malonyltransferase activity
J0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
J0004321molecular_functionfatty-acyl-CoA synthase activity
J0005515molecular_functionprotein binding
J0005737cellular_componentcytoplasm
J0005739cellular_componentmitochondrion
J0005811cellular_componentlipid droplet
J0005829cellular_componentcytosol
J0005835cellular_componentfatty acid synthase complex
J0006629biological_processlipid metabolic process
J0006631biological_processfatty acid metabolic process
J0006633biological_processfatty acid biosynthetic process
J0016297molecular_functionfatty acyl-[ACP] hydrolase activity
J0016409molecular_functionpalmitoyltransferase activity
J0016491molecular_functionoxidoreductase activity
J0016740molecular_functiontransferase activity
J0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
J0016787molecular_functionhydrolase activity
J0016829molecular_functionlyase activity
J0019171molecular_function(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
J0042759biological_processlong-chain fatty acid biosynthetic process
J0141148molecular_functionenoyl-[acyl-carrier-protein] reductase (NADPH) activity
K0003824molecular_functioncatalytic activity
K0004312molecular_functionfatty acid synthase activity
K0004313molecular_function[acyl-carrier-protein] S-acetyltransferase activity
K0004314molecular_function[acyl-carrier-protein] S-malonyltransferase activity
K0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
K0004321molecular_functionfatty-acyl-CoA synthase activity
K0005515molecular_functionprotein binding
K0005737cellular_componentcytoplasm
K0005739cellular_componentmitochondrion
K0005811cellular_componentlipid droplet
K0005829cellular_componentcytosol
K0005835cellular_componentfatty acid synthase complex
K0006629biological_processlipid metabolic process
K0006631biological_processfatty acid metabolic process
K0006633biological_processfatty acid biosynthetic process
K0016297molecular_functionfatty acyl-[ACP] hydrolase activity
K0016409molecular_functionpalmitoyltransferase activity
K0016491molecular_functionoxidoreductase activity
K0016740molecular_functiontransferase activity
K0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
K0016787molecular_functionhydrolase activity
K0016829molecular_functionlyase activity
K0019171molecular_function(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
K0042759biological_processlong-chain fatty acid biosynthetic process
K0141148molecular_functionenoyl-[acyl-carrier-protein] reductase (NADPH) activity
L0003824molecular_functioncatalytic activity
L0004312molecular_functionfatty acid synthase activity
L0004313molecular_function[acyl-carrier-protein] S-acetyltransferase activity
L0004314molecular_function[acyl-carrier-protein] S-malonyltransferase activity
L0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
L0004321molecular_functionfatty-acyl-CoA synthase activity
L0005515molecular_functionprotein binding
L0005737cellular_componentcytoplasm
L0005739cellular_componentmitochondrion
L0005811cellular_componentlipid droplet
L0005829cellular_componentcytosol
L0005835cellular_componentfatty acid synthase complex
L0006629biological_processlipid metabolic process
L0006631biological_processfatty acid metabolic process
L0006633biological_processfatty acid biosynthetic process
L0016297molecular_functionfatty acyl-[ACP] hydrolase activity
L0016409molecular_functionpalmitoyltransferase activity
L0016491molecular_functionoxidoreductase activity
L0016740molecular_functiontransferase activity
L0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
L0016787molecular_functionhydrolase activity
L0016829molecular_functionlyase activity
L0019171molecular_function(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
L0042759biological_processlong-chain fatty acid biosynthetic process
L0141148molecular_functionenoyl-[acyl-carrier-protein] reductase (NADPH) activity
M0005634cellular_componentnucleus
M0005737cellular_componentcytoplasm
M0005835cellular_componentfatty acid synthase complex
M0006633biological_processfatty acid biosynthetic process
M0008047molecular_functionenzyme activator activity
M0030674molecular_functionprotein-macromolecule adaptor activity
M0070682biological_processproteasome regulatory particle assembly
N0005634cellular_componentnucleus
N0005737cellular_componentcytoplasm
N0005835cellular_componentfatty acid synthase complex
N0006633biological_processfatty acid biosynthetic process
N0008047molecular_functionenzyme activator activity
N0030674molecular_functionprotein-macromolecule adaptor activity
N0070682biological_processproteasome regulatory particle assembly
O0005634cellular_componentnucleus
O0005737cellular_componentcytoplasm
O0005835cellular_componentfatty acid synthase complex
O0006633biological_processfatty acid biosynthetic process
O0008047molecular_functionenzyme activator activity
O0030674molecular_functionprotein-macromolecule adaptor activity
O0070682biological_processproteasome regulatory particle assembly
P0005634cellular_componentnucleus
P0005737cellular_componentcytoplasm
P0005835cellular_componentfatty acid synthase complex
P0006633biological_processfatty acid biosynthetic process
P0008047molecular_functionenzyme activator activity
P0030674molecular_functionprotein-macromolecule adaptor activity
P0070682biological_processproteasome regulatory particle assembly
Q0005634cellular_componentnucleus
Q0005737cellular_componentcytoplasm
Q0005835cellular_componentfatty acid synthase complex
Q0006633biological_processfatty acid biosynthetic process
Q0008047molecular_functionenzyme activator activity
Q0030674molecular_functionprotein-macromolecule adaptor activity
Q0070682biological_processproteasome regulatory particle assembly
R0005634cellular_componentnucleus
R0005737cellular_componentcytoplasm
R0005835cellular_componentfatty acid synthase complex
R0006633biological_processfatty acid biosynthetic process
R0008047molecular_functionenzyme activator activity
R0030674molecular_functionprotein-macromolecule adaptor activity
R0070682biological_processproteasome regulatory particle assembly
a0000287molecular_functionmagnesium ion binding
a0003824molecular_functioncatalytic activity
a0004312molecular_functionfatty acid synthase activity
a0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
a0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
a0004321molecular_functionfatty-acyl-CoA synthase activity
a0005515molecular_functionprotein binding
a0005739cellular_componentmitochondrion
a0005829cellular_componentcytosol
a0005835cellular_componentfatty acid synthase complex
a0006629biological_processlipid metabolic process
a0006631biological_processfatty acid metabolic process
a0006633biological_processfatty acid biosynthetic process
a0008897molecular_functionholo-[acyl-carrier-protein] synthase activity
a0016491molecular_functionoxidoreductase activity
a0016740molecular_functiontransferase activity
a0016746molecular_functionacyltransferase activity
a0042759biological_processlong-chain fatty acid biosynthetic process
a0046872molecular_functionmetal ion binding
b0000287molecular_functionmagnesium ion binding
b0003824molecular_functioncatalytic activity
b0004312molecular_functionfatty acid synthase activity
b0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
b0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
b0004321molecular_functionfatty-acyl-CoA synthase activity
b0005515molecular_functionprotein binding
b0005739cellular_componentmitochondrion
b0005829cellular_componentcytosol
b0005835cellular_componentfatty acid synthase complex
b0006629biological_processlipid metabolic process
b0006631biological_processfatty acid metabolic process
b0006633biological_processfatty acid biosynthetic process
b0008897molecular_functionholo-[acyl-carrier-protein] synthase activity
b0016491molecular_functionoxidoreductase activity
b0016740molecular_functiontransferase activity
b0016746molecular_functionacyltransferase activity
b0042759biological_processlong-chain fatty acid biosynthetic process
b0046872molecular_functionmetal ion binding
c0000287molecular_functionmagnesium ion binding
c0003824molecular_functioncatalytic activity
c0004312molecular_functionfatty acid synthase activity
c0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
c0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
c0004321molecular_functionfatty-acyl-CoA synthase activity
c0005515molecular_functionprotein binding
c0005739cellular_componentmitochondrion
c0005829cellular_componentcytosol
c0005835cellular_componentfatty acid synthase complex
c0006629biological_processlipid metabolic process
c0006631biological_processfatty acid metabolic process
c0006633biological_processfatty acid biosynthetic process
c0008897molecular_functionholo-[acyl-carrier-protein] synthase activity
c0016491molecular_functionoxidoreductase activity
c0016740molecular_functiontransferase activity
c0016746molecular_functionacyltransferase activity
c0042759biological_processlong-chain fatty acid biosynthetic process
c0046872molecular_functionmetal ion binding
d0000287molecular_functionmagnesium ion binding
d0003824molecular_functioncatalytic activity
d0004312molecular_functionfatty acid synthase activity
d0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
d0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
d0004321molecular_functionfatty-acyl-CoA synthase activity
d0005515molecular_functionprotein binding
d0005739cellular_componentmitochondrion
d0005829cellular_componentcytosol
d0005835cellular_componentfatty acid synthase complex
d0006629biological_processlipid metabolic process
d0006631biological_processfatty acid metabolic process
d0006633biological_processfatty acid biosynthetic process
d0008897molecular_functionholo-[acyl-carrier-protein] synthase activity
d0016491molecular_functionoxidoreductase activity
d0016740molecular_functiontransferase activity
d0016746molecular_functionacyltransferase activity
d0042759biological_processlong-chain fatty acid biosynthetic process
d0046872molecular_functionmetal ion binding
e0000287molecular_functionmagnesium ion binding
e0003824molecular_functioncatalytic activity
e0004312molecular_functionfatty acid synthase activity
e0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
e0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
e0004321molecular_functionfatty-acyl-CoA synthase activity
e0005515molecular_functionprotein binding
e0005739cellular_componentmitochondrion
e0005829cellular_componentcytosol
e0005835cellular_componentfatty acid synthase complex
e0006629biological_processlipid metabolic process
e0006631biological_processfatty acid metabolic process
e0006633biological_processfatty acid biosynthetic process
e0008897molecular_functionholo-[acyl-carrier-protein] synthase activity
e0016491molecular_functionoxidoreductase activity
e0016740molecular_functiontransferase activity
e0016746molecular_functionacyltransferase activity
e0042759biological_processlong-chain fatty acid biosynthetic process
e0046872molecular_functionmetal ion binding
f0000287molecular_functionmagnesium ion binding
f0003824molecular_functioncatalytic activity
f0004312molecular_functionfatty acid synthase activity
f0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
f0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
f0004321molecular_functionfatty-acyl-CoA synthase activity
f0005515molecular_functionprotein binding
f0005739cellular_componentmitochondrion
f0005829cellular_componentcytosol
f0005835cellular_componentfatty acid synthase complex
f0006629biological_processlipid metabolic process
f0006631biological_processfatty acid metabolic process
f0006633biological_processfatty acid biosynthetic process
f0008897molecular_functionholo-[acyl-carrier-protein] synthase activity
f0016491molecular_functionoxidoreductase activity
f0016740molecular_functiontransferase activity
f0016746molecular_functionacyltransferase activity
f0042759biological_processlong-chain fatty acid biosynthetic process
f0046872molecular_functionmetal ion binding
g0003824molecular_functioncatalytic activity
g0004312molecular_functionfatty acid synthase activity
g0004313molecular_function[acyl-carrier-protein] S-acetyltransferase activity
g0004314molecular_function[acyl-carrier-protein] S-malonyltransferase activity
g0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
g0004321molecular_functionfatty-acyl-CoA synthase activity
g0005515molecular_functionprotein binding
g0005737cellular_componentcytoplasm
g0005739cellular_componentmitochondrion
g0005811cellular_componentlipid droplet
g0005829cellular_componentcytosol
g0005835cellular_componentfatty acid synthase complex
g0006629biological_processlipid metabolic process
g0006631biological_processfatty acid metabolic process
g0006633biological_processfatty acid biosynthetic process
g0016297molecular_functionfatty acyl-[ACP] hydrolase activity
g0016409molecular_functionpalmitoyltransferase activity
g0016491molecular_functionoxidoreductase activity
g0016740molecular_functiontransferase activity
g0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
g0016787molecular_functionhydrolase activity
g0016829molecular_functionlyase activity
g0019171molecular_function(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
g0042759biological_processlong-chain fatty acid biosynthetic process
g0141148molecular_functionenoyl-[acyl-carrier-protein] reductase (NADPH) activity
h0003824molecular_functioncatalytic activity
h0004312molecular_functionfatty acid synthase activity
h0004313molecular_function[acyl-carrier-protein] S-acetyltransferase activity
h0004314molecular_function[acyl-carrier-protein] S-malonyltransferase activity
h0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
h0004321molecular_functionfatty-acyl-CoA synthase activity
h0005515molecular_functionprotein binding
h0005737cellular_componentcytoplasm
h0005739cellular_componentmitochondrion
h0005811cellular_componentlipid droplet
h0005829cellular_componentcytosol
h0005835cellular_componentfatty acid synthase complex
h0006629biological_processlipid metabolic process
h0006631biological_processfatty acid metabolic process
h0006633biological_processfatty acid biosynthetic process
h0016297molecular_functionfatty acyl-[ACP] hydrolase activity
h0016409molecular_functionpalmitoyltransferase activity
h0016491molecular_functionoxidoreductase activity
h0016740molecular_functiontransferase activity
h0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
h0016787molecular_functionhydrolase activity
h0016829molecular_functionlyase activity
h0019171molecular_function(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
h0042759biological_processlong-chain fatty acid biosynthetic process
h0141148molecular_functionenoyl-[acyl-carrier-protein] reductase (NADPH) activity
i0003824molecular_functioncatalytic activity
i0004312molecular_functionfatty acid synthase activity
i0004313molecular_function[acyl-carrier-protein] S-acetyltransferase activity
i0004314molecular_function[acyl-carrier-protein] S-malonyltransferase activity
i0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
i0004321molecular_functionfatty-acyl-CoA synthase activity
i0005515molecular_functionprotein binding
i0005737cellular_componentcytoplasm
i0005739cellular_componentmitochondrion
i0005811cellular_componentlipid droplet
i0005829cellular_componentcytosol
i0005835cellular_componentfatty acid synthase complex
i0006629biological_processlipid metabolic process
i0006631biological_processfatty acid metabolic process
i0006633biological_processfatty acid biosynthetic process
i0016297molecular_functionfatty acyl-[ACP] hydrolase activity
i0016409molecular_functionpalmitoyltransferase activity
i0016491molecular_functionoxidoreductase activity
i0016740molecular_functiontransferase activity
i0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
i0016787molecular_functionhydrolase activity
i0016829molecular_functionlyase activity
i0019171molecular_function(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
i0042759biological_processlong-chain fatty acid biosynthetic process
i0141148molecular_functionenoyl-[acyl-carrier-protein] reductase (NADPH) activity
j0003824molecular_functioncatalytic activity
j0004312molecular_functionfatty acid synthase activity
j0004313molecular_function[acyl-carrier-protein] S-acetyltransferase activity
j0004314molecular_function[acyl-carrier-protein] S-malonyltransferase activity
j0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
j0004321molecular_functionfatty-acyl-CoA synthase activity
j0005515molecular_functionprotein binding
j0005737cellular_componentcytoplasm
j0005739cellular_componentmitochondrion
j0005811cellular_componentlipid droplet
j0005829cellular_componentcytosol
j0005835cellular_componentfatty acid synthase complex
j0006629biological_processlipid metabolic process
j0006631biological_processfatty acid metabolic process
j0006633biological_processfatty acid biosynthetic process
j0016297molecular_functionfatty acyl-[ACP] hydrolase activity
j0016409molecular_functionpalmitoyltransferase activity
j0016491molecular_functionoxidoreductase activity
j0016740molecular_functiontransferase activity
j0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
j0016787molecular_functionhydrolase activity
j0016829molecular_functionlyase activity
j0019171molecular_function(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
j0042759biological_processlong-chain fatty acid biosynthetic process
j0141148molecular_functionenoyl-[acyl-carrier-protein] reductase (NADPH) activity
k0003824molecular_functioncatalytic activity
k0004312molecular_functionfatty acid synthase activity
k0004313molecular_function[acyl-carrier-protein] S-acetyltransferase activity
k0004314molecular_function[acyl-carrier-protein] S-malonyltransferase activity
k0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
k0004321molecular_functionfatty-acyl-CoA synthase activity
k0005515molecular_functionprotein binding
k0005737cellular_componentcytoplasm
k0005739cellular_componentmitochondrion
k0005811cellular_componentlipid droplet
k0005829cellular_componentcytosol
k0005835cellular_componentfatty acid synthase complex
k0006629biological_processlipid metabolic process
k0006631biological_processfatty acid metabolic process
k0006633biological_processfatty acid biosynthetic process
k0016297molecular_functionfatty acyl-[ACP] hydrolase activity
k0016409molecular_functionpalmitoyltransferase activity
k0016491molecular_functionoxidoreductase activity
k0016740molecular_functiontransferase activity
k0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
k0016787molecular_functionhydrolase activity
k0016829molecular_functionlyase activity
k0019171molecular_function(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
k0042759biological_processlong-chain fatty acid biosynthetic process
k0141148molecular_functionenoyl-[acyl-carrier-protein] reductase (NADPH) activity
l0003824molecular_functioncatalytic activity
l0004312molecular_functionfatty acid synthase activity
l0004313molecular_function[acyl-carrier-protein] S-acetyltransferase activity
l0004314molecular_function[acyl-carrier-protein] S-malonyltransferase activity
l0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
l0004321molecular_functionfatty-acyl-CoA synthase activity
l0005515molecular_functionprotein binding
l0005737cellular_componentcytoplasm
l0005739cellular_componentmitochondrion
l0005811cellular_componentlipid droplet
l0005829cellular_componentcytosol
l0005835cellular_componentfatty acid synthase complex
l0006629biological_processlipid metabolic process
l0006631biological_processfatty acid metabolic process
l0006633biological_processfatty acid biosynthetic process
l0016297molecular_functionfatty acyl-[ACP] hydrolase activity
l0016409molecular_functionpalmitoyltransferase activity
l0016491molecular_functionoxidoreductase activity
l0016740molecular_functiontransferase activity
l0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
l0016787molecular_functionhydrolase activity
l0016829molecular_functionlyase activity
l0019171molecular_function(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
l0042759biological_processlong-chain fatty acid biosynthetic process
l0141148molecular_functionenoyl-[acyl-carrier-protein] reductase (NADPH) activity
m0005634cellular_componentnucleus
m0005737cellular_componentcytoplasm
m0005835cellular_componentfatty acid synthase complex
m0006633biological_processfatty acid biosynthetic process
m0008047molecular_functionenzyme activator activity
m0030674molecular_functionprotein-macromolecule adaptor activity
m0070682biological_processproteasome regulatory particle assembly
n0005634cellular_componentnucleus
n0005737cellular_componentcytoplasm
n0005835cellular_componentfatty acid synthase complex
n0006633biological_processfatty acid biosynthetic process
n0008047molecular_functionenzyme activator activity
n0030674molecular_functionprotein-macromolecule adaptor activity
n0070682biological_processproteasome regulatory particle assembly
o0005634cellular_componentnucleus
o0005737cellular_componentcytoplasm
o0005835cellular_componentfatty acid synthase complex
o0006633biological_processfatty acid biosynthetic process
o0008047molecular_functionenzyme activator activity
o0030674molecular_functionprotein-macromolecule adaptor activity
o0070682biological_processproteasome regulatory particle assembly
p0005634cellular_componentnucleus
p0005737cellular_componentcytoplasm
p0005835cellular_componentfatty acid synthase complex
p0006633biological_processfatty acid biosynthetic process
p0008047molecular_functionenzyme activator activity
p0030674molecular_functionprotein-macromolecule adaptor activity
p0070682biological_processproteasome regulatory particle assembly
q0005634cellular_componentnucleus
q0005737cellular_componentcytoplasm
q0005835cellular_componentfatty acid synthase complex
q0006633biological_processfatty acid biosynthetic process
q0008047molecular_functionenzyme activator activity
q0030674molecular_functionprotein-macromolecule adaptor activity
q0070682biological_processproteasome regulatory particle assembly
r0005634cellular_componentnucleus
r0005737cellular_componentcytoplasm
r0005835cellular_componentfatty acid synthase complex
r0006633biological_processfatty acid biosynthetic process
r0008047molecular_functionenzyme activator activity
r0030674molecular_functionprotein-macromolecule adaptor activity
r0070682biological_processproteasome regulatory particle assembly
Functional Information from PROSITE/UniProt
site_idPS00012
Number of Residues16
DetailsPHOSPHOPANTETHEINE Phosphopantetheine attachment site. LVGGKSTVQNEILGDL
ChainResidueDetails
ALEU175-LEU190

site_idPS00606
Number of Residues17
DetailsKS3_1 Ketosynthase family 3 (KS3) active site signature. GPIktPVgACATSveSV
ChainResidueDetails
AGLY1296-VAL1312

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues900
DetailsDomain: {"description":"Carrier","evidences":[{"source":"PROSITE-ProRule","id":"PRU00258","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues6408
DetailsDomain: {"description":"Ketosynthase family 3 (KS3)","evidences":[{"source":"PROSITE-ProRule","id":"PRU01348","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues2388
DetailsRegion: {"description":"Beta-ketoacyl reductase"}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues36
DetailsActive site: {"description":"For beta-ketoacyl synthase activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU01348","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues264
DetailsBinding site: {}
ChainResidueDetails

site_idSWS_FT_FI6
Number of Residues24
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"19679086","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI7
Number of Residues12
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"15665377","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI8
Number of Residues12
DetailsModified residue: {"description":"O-(pantetheine 4'-phosphoryl)serine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00258","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17431182","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI9
Number of Residues12
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI10
Number of Residues24
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17330950","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI11
Number of Residues48
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22106047","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI12
Number of Residues1500
DetailsDomain: {"description":"MaoC-like"}
ChainResidueDetails

site_idSWS_FT_FI13
Number of Residues4656
DetailsRegion: {"description":"Enoyl reductase"}
ChainResidueDetails

site_idSWS_FT_FI14
Number of Residues5784
DetailsRegion: {"description":"Dehydratase"}
ChainResidueDetails

site_idSWS_FT_FI15
Number of Residues2616
DetailsRegion: {"description":"Malonyl/palmitoyl transferase"}
ChainResidueDetails

site_idSWS_FT_FI16
Number of Residues12
DetailsActive site: {"description":"For acetyltransferase activity","evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI17
Number of Residues12
DetailsActive site: {"description":"For malonyltransferase activity","evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI18
Number of Residues12
DetailsModified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI19
Number of Residues12
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI20
Number of Residues12
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

246031

PDB entries from 2025-12-10

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