Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0042981 | biological_process | regulation of apoptotic process |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0043065 | biological_process | positive regulation of apoptotic process |
| B | 0090200 | biological_process | positive regulation of release of cytochrome c from mitochondria |
| B | 0097193 | biological_process | intrinsic apoptotic signaling pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 401 |
| Chain | Residue |
| A | HIS252 |
| A | CL405 |
| B | ASP147 |
| B | HOH302 |
| B | HOH306 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 402 |
| Chain | Residue |
| A | HIS224 |
| A | CL404 |
| B | CL201 |
| B | HOH311 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue ZN A 403 |
| Chain | Residue |
| A | ASP236 |
| A | ASP242 |
| A | HIS277 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 404 |
| Chain | Residue |
| A | HIS224 |
| A | HIS252 |
| A | ZN402 |
| B | ARG142 |
| B | CL201 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 405 |
| Chain | Residue |
| A | HIS252 |
| A | LYS255 |
| A | ZN401 |
| B | ASP147 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 201 |
| Chain | Residue |
| A | ZN402 |
| A | CL404 |
| B | LEU148 |
Functional Information from PROSITE/UniProt
| site_id | PS01080 |
| Number of Residues | 20 |
| Details | BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. VFkDGvtNWGRIVTLIsFGA |
| Chain | Residue | Details |
| A | VAL253-ALA272 | |
| site_id | PS01258 |
| Number of Residues | 12 |
| Details | BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WLvkqRGWDgFV |
| Chain | Residue | Details |
| A | TRP305-VAL316 | |
| site_id | PS01259 |
| Number of Residues | 15 |
| Details | BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. AletLRrVGDGVQRN |
| Chain | Residue | Details |
| A | ALA209-ASN223 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Motif: {"description":"BH3"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Motif: {"description":"BH1"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 15 |
| Details | Motif: {"description":"BH2"} |
