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6QC8

Ovine respiratory complex I FRC open class 2

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
4L0005739cellular_componentmitochondrion
4L0005743cellular_componentmitochondrial inner membrane
4L0005747cellular_componentmitochondrial respiratory chain complex I
4L0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
4L0016020cellular_componentmembrane
4L0016651molecular_functionoxidoreductase activity, acting on NAD(P)H
4L0042773biological_processATP synthesis coupled electron transport
4L0055085biological_processtransmembrane transport
4L0070469cellular_componentrespirasome
A30005743cellular_componentmitochondrial inner membrane
A30005747cellular_componentmitochondrial respiratory chain complex I
A50022904biological_processrespiratory electron transport chain
A60005739cellular_componentmitochondrion
A60005743cellular_componentmitochondrial inner membrane
A60005747cellular_componentmitochondrial respiratory chain complex I
A60006979biological_processresponse to oxidative stress
A60016020cellular_componentmembrane
A60031966cellular_componentmitochondrial membrane
A60032981biological_processmitochondrial respiratory chain complex I assembly
A60070469cellular_componentrespirasome
A70005743cellular_componentmitochondrial inner membrane
A70005747cellular_componentmitochondrial respiratory chain complex I
A70006120biological_processmitochondrial electron transport, NADH to ubiquinone
A70016020cellular_componentmembrane
A70042773biological_processATP synthesis coupled electron transport
A80006120biological_processmitochondrial electron transport, NADH to ubiquinone
AA0006633biological_processfatty acid biosynthetic process
AB0006633biological_processfatty acid biosynthetic process
AJ0005747cellular_componentmitochondrial respiratory chain complex I
AJ0006120biological_processmitochondrial electron transport, NADH to ubiquinone
AK0032981biological_processmitochondrial respiratory chain complex I assembly
AL0016020cellular_componentmembrane
AL0032981biological_processmitochondrial respiratory chain complex I assembly
B10005739cellular_componentmitochondrion
B10005743cellular_componentmitochondrial inner membrane
B10005747cellular_componentmitochondrial respiratory chain complex I
B10016020cellular_componentmembrane
B20005743cellular_componentmitochondrial inner membrane
B20005747cellular_componentmitochondrial respiratory chain complex I
B30005739cellular_componentmitochondrion
B30022900biological_processelectron transport chain
B40005739cellular_componentmitochondrion
B40005743cellular_componentmitochondrial inner membrane
B40005747cellular_componentmitochondrial respiratory chain complex I
B40016020cellular_componentmembrane
B60005743cellular_componentmitochondrial inner membrane
B60005747cellular_componentmitochondrial respiratory chain complex I
B60006120biological_processmitochondrial electron transport, NADH to ubiquinone
B60016020cellular_componentmembrane
B60042775biological_processmitochondrial ATP synthesis coupled electron transport
B70005739cellular_componentmitochondrion
B80005739cellular_componentmitochondrion
B80005747cellular_componentmitochondrial respiratory chain complex I
B80006120biological_processmitochondrial electron transport, NADH to ubiquinone
B90006120biological_processmitochondrial electron transport, NADH to ubiquinone
C10005739cellular_componentmitochondrion
C10005747cellular_componentmitochondrial respiratory chain complex I
C20005737cellular_componentcytoplasm
C20005739cellular_componentmitochondrion
C20005743cellular_componentmitochondrial inner membrane
C20005747cellular_componentmitochondrial respiratory chain complex I
C20006120biological_processmitochondrial electron transport, NADH to ubiquinone
C20016020cellular_componentmembrane
C20032981biological_processmitochondrial respiratory chain complex I assembly
C20070469cellular_componentrespirasome
D10003954molecular_functionNADH dehydrogenase activity
D10005739cellular_componentmitochondrion
D10005743cellular_componentmitochondrial inner membrane
D10005747cellular_componentmitochondrial respiratory chain complex I
D10006120biological_processmitochondrial electron transport, NADH to ubiquinone
D10008137molecular_functionNADH dehydrogenase (ubiquinone) activity
D10009060biological_processaerobic respiration
D10016020cellular_componentmembrane
D10031966cellular_componentmitochondrial membrane
D10032981biological_processmitochondrial respiratory chain complex I assembly
D10055085biological_processtransmembrane transport
D10070469cellular_componentrespirasome
D20005739cellular_componentmitochondrion
D20005743cellular_componentmitochondrial inner membrane
D20005747cellular_componentmitochondrial respiratory chain complex I
D20006120biological_processmitochondrial electron transport, NADH to ubiquinone
D20008137molecular_functionNADH dehydrogenase (ubiquinone) activity
D20016020cellular_componentmembrane
D20032981biological_processmitochondrial respiratory chain complex I assembly
D20055085biological_processtransmembrane transport
D20070469cellular_componentrespirasome
D20072593biological_processreactive oxygen species metabolic process
D30005739cellular_componentmitochondrion
D30005743cellular_componentmitochondrial inner membrane
D30005747cellular_componentmitochondrial respiratory chain complex I
D30006120biological_processmitochondrial electron transport, NADH to ubiquinone
D30008137molecular_functionNADH dehydrogenase (ubiquinone) activity
D30016020cellular_componentmembrane
D30055085biological_processtransmembrane transport
D30070469cellular_componentrespirasome
D40003954molecular_functionNADH dehydrogenase activity
D40005739cellular_componentmitochondrion
D40005743cellular_componentmitochondrial inner membrane
D40005747cellular_componentmitochondrial respiratory chain complex I
D40006120biological_processmitochondrial electron transport, NADH to ubiquinone
D40008137molecular_functionNADH dehydrogenase (ubiquinone) activity
D40009060biological_processaerobic respiration
D40015990biological_processelectron transport coupled proton transport
D40016020cellular_componentmembrane
D40032981biological_processmitochondrial respiratory chain complex I assembly
D40042773biological_processATP synthesis coupled electron transport
D40045271cellular_componentrespiratory chain complex I
D40048039molecular_functionubiquinone binding
D40055085biological_processtransmembrane transport
D40070469cellular_componentrespirasome
D50003954molecular_functionNADH dehydrogenase activity
D50005739cellular_componentmitochondrion
D50005743cellular_componentmitochondrial inner membrane
D50005747cellular_componentmitochondrial respiratory chain complex I
D50006120biological_processmitochondrial electron transport, NADH to ubiquinone
D50008137molecular_functionNADH dehydrogenase (ubiquinone) activity
D50015990biological_processelectron transport coupled proton transport
D50016020cellular_componentmembrane
D50032981biological_processmitochondrial respiratory chain complex I assembly
D50042773biological_processATP synthesis coupled electron transport
D50055085biological_processtransmembrane transport
D50070469cellular_componentrespirasome
D60005739cellular_componentmitochondrion
D60005743cellular_componentmitochondrial inner membrane
D60005747cellular_componentmitochondrial respiratory chain complex I
D60006120biological_processmitochondrial electron transport, NADH to ubiquinone
D60008137molecular_functionNADH dehydrogenase (ubiquinone) activity
D60016020cellular_componentmembrane
D60032981biological_processmitochondrial respiratory chain complex I assembly
D60055085biological_processtransmembrane transport
D60070469cellular_componentrespirasome
S10008137molecular_functionNADH dehydrogenase (ubiquinone) activity
S10016020cellular_componentmembrane
S10016491molecular_functionoxidoreductase activity
S10016651molecular_functionoxidoreductase activity, acting on NAD(P)H
S10042773biological_processATP synthesis coupled electron transport
S10051536molecular_functioniron-sulfur cluster binding
S20016651molecular_functionoxidoreductase activity, acting on NAD(P)H
S20048038molecular_functionquinone binding
S20051287molecular_functionNAD binding
S30008137molecular_functionNADH dehydrogenase (ubiquinone) activity
S30016651molecular_functionoxidoreductase activity, acting on NAD(P)H
S40022900biological_processelectron transport chain
S60005747cellular_componentmitochondrial respiratory chain complex I
S60006120biological_processmitochondrial electron transport, NADH to ubiquinone
S70008137molecular_functionNADH dehydrogenase (ubiquinone) activity
S70048038molecular_functionquinone binding
S70051536molecular_functioniron-sulfur cluster binding
S70051539molecular_function4 iron, 4 sulfur cluster binding
S80016020cellular_componentmembrane
S80016651molecular_functionoxidoreductase activity, acting on NAD(P)H
S80051539molecular_function4 iron, 4 sulfur cluster binding
V10003954molecular_functionNADH dehydrogenase activity
V10005739cellular_componentmitochondrion
V10005743cellular_componentmitochondrial inner membrane
V10005747cellular_componentmitochondrial respiratory chain complex I
V10006120biological_processmitochondrial electron transport, NADH to ubiquinone
V10008137molecular_functionNADH dehydrogenase (ubiquinone) activity
V10010181molecular_functionFMN binding
V10016020cellular_componentmembrane
V10045271cellular_componentrespiratory chain complex I
V10046872molecular_functionmetal ion binding
V10051287molecular_functionNAD binding
V10051536molecular_functioniron-sulfur cluster binding
V10051539molecular_function4 iron, 4 sulfur cluster binding
V10055085biological_processtransmembrane transport
V10070469cellular_componentrespirasome
V20016491molecular_functionoxidoreductase activity
V30005739cellular_componentmitochondrion
V30005747cellular_componentmitochondrial respiratory chain complex I
Functional Information from PDB Data
site_idAC1
Number of Residues9
Detailsbinding site for residue SF4 V1 500
ChainResidue
V1PRO203
V1SER358
V1CYS359
V1GLY360
V1GLN361
V1CYS362
V1CYS365
V1THR403
V1CYS405

site_idAC2
Number of Residues15
Detailsbinding site for residue FMN V1 501
ChainResidue
V1GLY67
V1ARG68
V1GLY69
V1ALA71
V1LYS78
V1ASN96
V1ASP98
V1GLU99
V1GLY100
V1GLY187
V1GLU188
V1GLU189
V1ALA223
V1ASN224
V1THR227

site_idAC3
Number of Residues6
Detailsbinding site for residue FES V2 300
ChainResidue
V2CYS103
V2THR105
V2CYS108
V2CYS144
V2ALA147
V2CYS148

site_idAC4
Number of Residues10
Detailsbinding site for residue SF4 S1 801
ChainResidue
S1HIS101
S1ASP104
S1CYS105
S1CYS108
S1GLN110
S1CYS114
S1GLN117
S1ARG152
S1VAL205
S1GLY206

site_idAC5
Number of Residues7
Detailsbinding site for residue SF4 S1 802
ChainResidue
S1CYS153
S1ILE154
S1CYS156
S1THR157
S1CYS159
S1CYS203
S1VAL205

site_idAC6
Number of Residues7
Detailsbinding site for residue FES S1 803
ChainResidue
S1CYS41
S1TYR42
S1GLY50
S1CYS52
S1ARG53
S1CYS55
S1CYS69

site_idAC7
Number of Residues9
Detailsbinding site for residue SF4 S7 300
ChainResidue
S2ARG105
S7ALA53
S7CYS54
S7CYS55
S7GLY90
S7SER118
S7CYS119
S7CYS149
S7PRO150

site_idAC8
Number of Residues11
Detailsbinding site for residue SF4 S8 201
ChainResidue
S8HIS65
S8CYS87
S8PRO88
S8ILE92
S8CYS116
S8ILE117
S8TYR118
S8CYS119
S8GLY120
S8CYS122
S8GLU133

site_idAC9
Number of Residues9
Detailsbinding site for residue SF4 S8 202
ChainResidue
S8CYS77
S8ALA79
S8CYS80
S8LYS81
S8CYS83
S8ILE94
S8TYR109
S8CYS126
S8VAL128

site_idAD1
Number of Residues5
Detailsbinding site for residue ZN S6 300
ChainResidue
S6CYS59
S6HIS68
S6VAL71
S6CYS84
S6CYS87

site_idAD2
Number of Residues16
Detailsbinding site for residue NDP A9 401
ChainResidue
A9HIS134
A9LYS149
A9ASP170
A9ILE171
A9ARG177
A9GLY25
A9THR27
A9GLY28
A9PHE29
A9ARG50
A9LEU94
A9VAL95
A9GLY96
A9ARG97
A9GLU98
A9ILE132

site_idAD3
Number of Residues8
Detailsbinding site for residue ZMP AA 101
ChainResidue
A6ARG32
A6TRP38
A6PHE66
A6ASN69
A6ALA70
A6LEU81
A6PHE106
AASER44

site_idAD4
Number of Residues8
Detailsbinding site for residue 3PE D1 501
ChainResidue
AMTYR142
AMTHR143
D1MET98
D1ASN99
D3LEU3
D6LEU45
D6ASN46
D6LEU54

site_idAD5
Number of Residues9
Detailsbinding site for residue CDL D5 901
ChainResidue
B5LEU22
D4LEU354
D5ASN23
D5PHE24
D5GLN116
D5LYS119
D5TYR120
D5LEU123
D5MET150

site_idAD6
Number of Residues9
Detailsbinding site for residue 3PE D5 902
ChainResidue
B8ARG88
B8ASP90
D5LEU169
D5GLN170
D5TYR174
D5HIS534
D5THR537
D5PRO538
D5ASN541

site_idAD7
Number of Residues8
Detailsbinding site for residue 3PE D4 501
ChainResidue
D2LEU288
D2TYR291
D4LEU147
D4TYR148
D4PHE151
D4TYR152
D5SER567
S2TYR14

site_idAD8
Number of Residues7
Detailsbinding site for residue PC1 AK 201
ChainResidue
AKGLU130
AKTRP132
D2ASP274
D2ILE276
D2ILE277
D4TYR166
D4SER191

site_idAD9
Number of Residues8
Detailsbinding site for residue ZMP AB 101
ChainResidue
ABASP43
ABSER44
B9GLN12
B9ARG46
B9PHE47
B9HIS50
B9LYS51
B9GLU69

Functional Information from PROSITE/UniProt
site_idPS00641
Number of Residues18
DetailsCOMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PrfCYherlsvaGnCRmC
ChainResidueDetails
S1PRO38-CYS55

site_idPS00642
Number of Residues13
DetailsCOMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPiCDqGGeCdLQ
ChainResidueDetails
S1CYS105-GLN117

site_idPS00643
Number of Residues11
DetailsCOMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIqCtRCIrF
ChainResidueDetails
S1ARG152-PHE162

site_idPS00198
Number of Residues12
Details4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaVCP
ChainResidueDetails
S8CYS77-PRO88
S8CYS116-PRO127

site_idPS00667
Number of Residues16
DetailsCOMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GLLQpIaDAIKLFiKE
ChainResidueDetails
D1GLY44-GLU59

site_idPS00668
Number of Residues14
DetailsCOMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLTEGEseLVs.G
ChainResidueDetails
D1PRO197-GLY210

site_idPS01099
Number of Residues19
DetailsCOMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DklFTlieveCLGaCvnAP
ChainResidueDetails
V2ASP134-PRO152

site_idPS01150
Number of Residues17
DetailsCOMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GcDRIVPVDIYvPgCPP
ChainResidueDetails
S7GLY135-PRO151

site_idPS00542
Number of Residues22
DetailsCOMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREiwDMFgvffanHpdlRrIL
ChainResidueDetails
S3GLU131-LEU152

site_idPS00644
Number of Residues16
DetailsCOMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GAGAYICGEETALIES
ChainResidueDetails
V1GLY180-SER195

site_idPS00645
Number of Residues12
DetailsCOMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGqCtPCReG
ChainResidueDetails
V1GLU357-GLY368

site_idPS00012
Number of Residues16
DetailsPHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGLDSLDQVEIIMAM
ChainResidueDetails
ABASP39-MET54

site_idPS00018
Number of Residues13
DetailsEF_HAND_1 EF-hand calcium-binding domain. DIDAEKLMCpqEI
ChainResidueDetails
ABASP64-ILE76

site_idPS00535
Number of Residues12
DetailsCOMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLiEyK
ChainResidueDetails
S2LEU83-LYS94

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues220
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
D2PRO3-SER23
D2ASP274-MET294
D2LEU325-ILE345
D5MET366-LEU386
D5LEU413-GLY433
D5LEU457-ILE477
D5TYR485-SER505
D5GLY582-LEU602
D2HIS25-MET45
D2SER67-MET87
D2MET96-PRO116
D2ILE122-LEU142
D2ILE145-GLY165
D2ILE178-PRO198
D2MET200-MET220
D2ALA237-LEU257

217705

PDB entries from 2024-03-27

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