Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6QBX

Ovine respiratory supercomplex I+III2 closed class.

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
4L0005739cellular_componentmitochondrion
4L0005743cellular_componentmitochondrial inner membrane
4L0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
4L0016651molecular_functionoxidoreductase activity, acting on NAD(P)H
4L0030964cellular_componentNADH dehydrogenase complex
4L0042773biological_processATP synthesis coupled electron transport
4L0045271cellular_componentrespiratory chain complex I
4L1902600biological_processproton transmembrane transport
A30005743cellular_componentmitochondrial inner membrane
A30045271cellular_componentrespiratory chain complex I
A50022904biological_processrespiratory electron transport chain
A60005739cellular_componentmitochondrion
A60005743cellular_componentmitochondrial inner membrane
A60006979biological_processresponse to oxidative stress
A60031966cellular_componentmitochondrial membrane
A60032981biological_processmitochondrial respiratory chain complex I assembly
A60045271cellular_componentrespiratory chain complex I
A70005739cellular_componentmitochondrion
A70005743cellular_componentmitochondrial inner membrane
A70006120biological_processmitochondrial electron transport, NADH to ubiquinone
A70042773biological_processATP synthesis coupled electron transport
A80006120biological_processmitochondrial electron transport, NADH to ubiquinone
AA0006633biological_processfatty acid biosynthetic process
AB0006633biological_processfatty acid biosynthetic process
AJ0006120biological_processmitochondrial electron transport, NADH to ubiquinone
AK0032981biological_processmitochondrial respiratory chain complex I assembly
AL0016020cellular_componentmembrane
AL0032981biological_processmitochondrial respiratory chain complex I assembly
B10005739cellular_componentmitochondrion
B10005743cellular_componentmitochondrial inner membrane
B20005743cellular_componentmitochondrial inner membrane
B20045271cellular_componentrespiratory chain complex I
B30005739cellular_componentmitochondrion
B30022900biological_processelectron transport chain
B40005739cellular_componentmitochondrion
B40005743cellular_componentmitochondrial inner membrane
B60005739cellular_componentmitochondrion
B60005743cellular_componentmitochondrial inner membrane
B60006120biological_processmitochondrial electron transport, NADH to ubiquinone
B60042775biological_processmitochondrial ATP synthesis coupled electron transport
B70005739cellular_componentmitochondrion
B80005739cellular_componentmitochondrion
B80006120biological_processmitochondrial electron transport, NADH to ubiquinone
B90006120biological_processmitochondrial electron transport, NADH to ubiquinone
C10005739cellular_componentmitochondrion
C10045271cellular_componentrespiratory chain complex I
C20005737cellular_componentcytoplasm
C20005739cellular_componentmitochondrion
C20005743cellular_componentmitochondrial inner membrane
C20006120biological_processmitochondrial electron transport, NADH to ubiquinone
C20032981biological_processmitochondrial respiratory chain complex I assembly
C20045271cellular_componentrespiratory chain complex I
D10003954molecular_functionNADH dehydrogenase activity
D10005739cellular_componentmitochondrion
D10005743cellular_componentmitochondrial inner membrane
D10006120biological_processmitochondrial electron transport, NADH to ubiquinone
D10008137molecular_functionNADH dehydrogenase (ubiquinone) activity
D10009060biological_processaerobic respiration
D10016020cellular_componentmembrane
D10031966cellular_componentmitochondrial membrane
D10032981biological_processmitochondrial respiratory chain complex I assembly
D10045271cellular_componentrespiratory chain complex I
D11902600biological_processproton transmembrane transport
D20005739cellular_componentmitochondrion
D20005743cellular_componentmitochondrial inner membrane
D20006120biological_processmitochondrial electron transport, NADH to ubiquinone
D20008137molecular_functionNADH dehydrogenase (ubiquinone) activity
D20032981biological_processmitochondrial respiratory chain complex I assembly
D20045271cellular_componentrespiratory chain complex I
D20072593biological_processreactive oxygen species metabolic process
D21902600biological_processproton transmembrane transport
D30005739cellular_componentmitochondrion
D30005743cellular_componentmitochondrial inner membrane
D30006120biological_processmitochondrial electron transport, NADH to ubiquinone
D30008137molecular_functionNADH dehydrogenase (ubiquinone) activity
D30030964cellular_componentNADH dehydrogenase complex
D30045271cellular_componentrespiratory chain complex I
D31902600biological_processproton transmembrane transport
D40003954molecular_functionNADH dehydrogenase activity
D40005739cellular_componentmitochondrion
D40005743cellular_componentmitochondrial inner membrane
D40006120biological_processmitochondrial electron transport, NADH to ubiquinone
D40008137molecular_functionNADH dehydrogenase (ubiquinone) activity
D40009060biological_processaerobic respiration
D40015990biological_processelectron transport coupled proton transport
D40032981biological_processmitochondrial respiratory chain complex I assembly
D40042773biological_processATP synthesis coupled electron transport
D40045271cellular_componentrespiratory chain complex I
D40048039molecular_functionubiquinone binding
D50003954molecular_functionNADH dehydrogenase activity
D50005739cellular_componentmitochondrion
D50005743cellular_componentmitochondrial inner membrane
D50006120biological_processmitochondrial electron transport, NADH to ubiquinone
D50008137molecular_functionNADH dehydrogenase (ubiquinone) activity
D50015990biological_processelectron transport coupled proton transport
D50032981biological_processmitochondrial respiratory chain complex I assembly
D50042773biological_processATP synthesis coupled electron transport
D50045271cellular_componentrespiratory chain complex I
D60005739cellular_componentmitochondrion
D60005743cellular_componentmitochondrial inner membrane
D60006120biological_processmitochondrial electron transport, NADH to ubiquinone
D60008137molecular_functionNADH dehydrogenase (ubiquinone) activity
D60032981biological_processmitochondrial respiratory chain complex I assembly
D60045271cellular_componentrespiratory chain complex I
D61902600biological_processproton transmembrane transport
S10008137molecular_functionNADH dehydrogenase (ubiquinone) activity
S10016020cellular_componentmembrane
S10016491molecular_functionoxidoreductase activity
S10016651molecular_functionoxidoreductase activity, acting on NAD(P)H
S10042773biological_processATP synthesis coupled electron transport
S10051536molecular_functioniron-sulfur cluster binding
S20016651molecular_functionoxidoreductase activity, acting on NAD(P)H
S20048038molecular_functionquinone binding
S20051287molecular_functionNAD binding
S30008137molecular_functionNADH dehydrogenase (ubiquinone) activity
S30016651molecular_functionoxidoreductase activity, acting on NAD(P)H
S40022900biological_processelectron transport chain
S60006120biological_processmitochondrial electron transport, NADH to ubiquinone
S70008137molecular_functionNADH dehydrogenase (ubiquinone) activity
S70048038molecular_functionquinone binding
S70051536molecular_functioniron-sulfur cluster binding
S70051539molecular_function4 iron, 4 sulfur cluster binding
S80016020cellular_componentmembrane
S80016651molecular_functionoxidoreductase activity, acting on NAD(P)H
S80051539molecular_function4 iron, 4 sulfur cluster binding
V10005739cellular_componentmitochondrion
V10005743cellular_componentmitochondrial inner membrane
V10006120biological_processmitochondrial electron transport, NADH to ubiquinone
V10008137molecular_functionNADH dehydrogenase (ubiquinone) activity
V10010181molecular_functionFMN binding
V10046872molecular_functionmetal ion binding
V10051287molecular_functionNAD binding
V10051539molecular_function4 iron, 4 sulfur cluster binding
V11902600biological_processproton transmembrane transport
V20016491molecular_functionoxidoreductase activity
V30005739cellular_componentmitochondrion
V30045271cellular_componentrespiratory chain complex I
a10005739cellular_componentmitochondrion
a10005743cellular_componentmitochondrial inner membrane
a10006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
a10031625molecular_functionubiquitin protein ligase binding
a10045275cellular_componentrespiratory chain complex III
a10046872molecular_functionmetal ion binding
a20004222molecular_functionmetalloendopeptidase activity
a20006508biological_processproteolysis
a20046872molecular_functionmetal ion binding
a30005739cellular_componentmitochondrion
a30005743cellular_componentmitochondrial inner membrane
a30006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
a30031625molecular_functionubiquitin protein ligase binding
a30045275cellular_componentrespiratory chain complex III
a30046872molecular_functionmetal ion binding
a40004222molecular_functionmetalloendopeptidase activity
a40006508biological_processproteolysis
a40046872molecular_functionmetal ion binding
b10005739cellular_componentmitochondrion
b10005743cellular_componentmitochondrial inner membrane
b10006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
b10008121molecular_functionubiquinol-cytochrome-c reductase activity
b10009055molecular_functionelectron transfer activity
b10016020cellular_componentmembrane
b10016491molecular_functionoxidoreductase activity
b10022904biological_processrespiratory electron transport chain
b10045275cellular_componentrespiratory chain complex III
b10046872molecular_functionmetal ion binding
b11902600biological_processproton transmembrane transport
b20005739cellular_componentmitochondrion
b20005743cellular_componentmitochondrial inner membrane
b20006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
b20008121molecular_functionubiquinol-cytochrome-c reductase activity
b20009055molecular_functionelectron transfer activity
b20016020cellular_componentmembrane
b20016491molecular_functionoxidoreductase activity
b20022904biological_processrespiratory electron transport chain
b20045275cellular_componentrespiratory chain complex III
b20046872molecular_functionmetal ion binding
b21902600biological_processproton transmembrane transport
c10009055molecular_functionelectron transfer activity
c10020037molecular_functionheme binding
c20009055molecular_functionelectron transfer activity
c20020037molecular_functionheme binding
d10005739cellular_componentmitochondrion
d10005743cellular_componentmitochondrial inner membrane
d10006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
d10045275cellular_componentrespiratory chain complex III
d20005739cellular_componentmitochondrion
d20005743cellular_componentmitochondrial inner membrane
d20006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
d20045275cellular_componentrespiratory chain complex III
f10008121molecular_functionubiquinol-cytochrome-c reductase activity
f10016020cellular_componentmembrane
f10051537molecular_function2 iron, 2 sulfur cluster binding
f20008121molecular_functionubiquinol-cytochrome-c reductase activity
f20016020cellular_componentmembrane
f20051537molecular_function2 iron, 2 sulfur cluster binding
h10006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
h20006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
i10006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
i10045275cellular_componentrespiratory chain complex III
i20006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
i20045275cellular_componentrespiratory chain complex III
q10005739cellular_componentmitochondrion
q10005743cellular_componentmitochondrial inner membrane
q10006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
q10045275cellular_componentrespiratory chain complex III
q20005739cellular_componentmitochondrion
q20005743cellular_componentmitochondrial inner membrane
q20006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
q20045275cellular_componentrespiratory chain complex III
Functional Information from PDB Data
site_idAC1
Number of Residues14
Detailsbinding site for residue HEM b1 401
ChainResidue
b1GLN44
b1LEU133
b1PRO134
b1HIS182
b1PHE183
b1PRO186
b1GLY48
b1VAL66
b1ARG80
b1HIS83
b1ALA84
b1ALA87
b1PHE90
b1GLY130

site_idAC2
Number of Residues14
Detailsbinding site for residue HEM b1 402
ChainResidue
b1TRP31
b1GLY34
b1LEU37
b1LEU94
b1HIS97
b1ARG100
b1SER106
b1TRP113
b1GLY116
b1VAL117
b1LEU119
b1HIS196
b1LEU200
b1ASN206

site_idAC3
Number of Residues11
Detailsbinding site for residue HEC c1 501
ChainResidue
c1CYS37
c1SER39
c1CYS40
c1HIS41
c1ALA108
c1LEU109
c1ARG120
c1PHE152
c1ILE157
c1MET159
c1PRO162

site_idAC4
Number of Residues6
Detailsbinding site for residue FES f1 501
ChainResidue
f1CYS139
f1HIS141
f1LEU142
f1CYS158
f1HIS161
f1SER163

site_idAC5
Number of Residues12
Detailsbinding site for residue HEM b2 401
ChainResidue
b2GLY48
b2LEU51
b2ARG80
b2HIS83
b2ALA87
b2GLY130
b2PRO134
b2PHE179
b2HIS182
b2PHE183
b2PRO186
b2ASN255

site_idAC6
Number of Residues12
Detailsbinding site for residue HEM b2 402
ChainResidue
b2TRP31
b2GLY34
b2LEU37
b2HIS97
b2ARG100
b2SER106
b2TRP113
b2GLY116
b2LEU119
b2HIS196
b2LEU200
b2ASN206

site_idAC7
Number of Residues10
Detailsbinding site for residue HEC c2 501
ChainResidue
c2CYS37
c2CYS40
c2HIS41
c2ASN105
c2ALA108
c2ARG120
c2TYR126
c2PHE152
c2MET159
c2VAL185

site_idAC8
Number of Residues7
Detailsbinding site for residue FES f2 501
ChainResidue
f2CYS139
f2HIS141
f2LEU142
f2CYS144
f2CYS158
f2HIS161
f2SER163

site_idAC9
Number of Residues8
Detailsbinding site for residue SF4 V1 500
ChainResidue
V1PRO203
V1SER358
V1CYS359
V1GLN361
V1CYS362
V1CYS365
V1THR403
V1CYS405

site_idAD1
Number of Residues14
Detailsbinding site for residue FMN V1 501
ChainResidue
V1ASN96
V1GLY100
V1LYS106
V1TYR184
V1GLY187
V1GLU188
V1GLU189
V1VAL222
V1ASN224
V1GLY67
V1ARG68
V1GLY69
V1PHE73
V1LYS78

site_idAD2
Number of Residues8
Detailsbinding site for residue FES V2 300
ChainResidue
V2CYS103
V2THR105
V2CYS108
V2CYS144
V2LEU145
V2GLY146
V2ALA147
V2CYS148

site_idAD3
Number of Residues8
Detailsbinding site for residue SF4 S1 801
ChainResidue
S1HIS101
S1CYS105
S1CYS108
S1CYS114
S1LEU116
S1GLN117
S1VAL205
S1GLY206

site_idAD4
Number of Residues6
Detailsbinding site for residue SF4 S1 802
ChainResidue
S1CYS153
S1CYS156
S1THR157
S1CYS159
S1CYS203
S1VAL205

site_idAD5
Number of Residues7
Detailsbinding site for residue FES S1 803
ChainResidue
S1CYS41
S1TYR42
S1GLY50
S1CYS52
S1ARG53
S1CYS55
S1CYS69

site_idAD6
Number of Residues13
Detailsbinding site for residue 3PE S2 501
ChainResidue
D2LEU288
D2TYR291
D4LEU147
D4TYR148
D4PHE151
D4TYR152
D5LEU562
D5SER567
D5GLN570
S2TRP10
S2GLN13
S2TYR14
S2TYR20

site_idAD7
Number of Residues9
Detailsbinding site for residue SF4 S7 300
ChainResidue
S2ARG105
S7CYS54
S7CYS55
S7GLY90
S7SER118
S7CYS119
S7GLY148
S7CYS149
S7PRO150

site_idAD8
Number of Residues10
Detailsbinding site for residue SF4 S8 201
ChainResidue
S8HIS65
S8CYS87
S8PRO88
S8CYS116
S8ILE117
S8TYR118
S8CYS119
S8GLY120
S8CYS122
S8GLU133

site_idAD9
Number of Residues9
Detailsbinding site for residue SF4 S8 202
ChainResidue
S8CYS77
S8ALA79
S8CYS80
S8LYS81
S8CYS83
S8ILE94
S8TYR109
S8CYS126
S8ILE131

site_idAE1
Number of Residues5
Detailsbinding site for residue ZN S6 300
ChainResidue
S6CYS59
S6HIS68
S6VAL71
S6CYS84
S6CYS87

site_idAE2
Number of Residues22
Detailsbinding site for residue NDP A9 401
ChainResidue
A9GLY25
A9ALA26
A9THR27
A9GLY28
A9PHE29
A9ARG50
A9CYS51
A9LEU94
A9VAL95
A9GLY96
A9ARG97
A9GLU98
A9PHE104
A9ILE132
A9HIS134
A9TYR145
A9LYS149
A9PRO168
A9ALA169
A9ASP170
A9ILE171
A9ARG177

site_idAE3
Number of Residues9
Detailsbinding site for residue ZMP AA 101
ChainResidue
A6LYS28
A6VAL31
A6TRP38
A6MET65
A6PHE66
A6ASN69
A6LEU81
AAASP43
AASER44

site_idAE4
Number of Residues10
Detailsbinding site for residue 3PE D5 701
ChainResidue
B8ARG88
B8ASP90
D4LEU405
D5THR166
D5LEU169
D5GLN170
D5TYR174
D5HIS534
D5PRO538
D5ASN541

site_idAE5
Number of Residues6
Detailsbinding site for residue PC1 AK 201
ChainResidue
AKTRP132
D2ILE276
D2ILE277
D4TYR166
D4SER191
D4ALA198

site_idAE6
Number of Residues13
Detailsbinding site for residue ZMP AB 101
ChainResidue
ABASP43
ABSER44
B9HIS11
B9GLN12
B9ARG46
B9PHE47
B9HIS50
B9GLU53
B9ALA59
B9LEU62
B9LEU63
B9ALA66
B9GLU69

Functional Information from PROSITE/UniProt
site_idPS00012
Number of Residues16
DetailsPHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGLDSLDQVEIIMAM
ChainResidueDetails
AAASP39-MET54

site_idPS00018
Number of Residues13
DetailsEF_HAND_1 EF-hand calcium-binding domain. DIDAEKLMCpqEI
ChainResidueDetails
AAASP64-ILE76

site_idPS00143
Number of Residues24
DetailsINSULINASE Insulinase family, zinc-binding region signature. GsryenfnnlGtSHLLRLAsSlTT
ChainResidueDetails
a2GLY54-THR77

site_idPS00198
Number of Residues12
Details4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaVCP
ChainResidueDetails
S8CYS77-PRO88
S8CYS116-PRO127

site_idPS00535
Number of Residues12
DetailsCOMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLiEyK
ChainResidueDetails
S2LEU83-LYS94

site_idPS00542
Number of Residues22
DetailsCOMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREiwDMFgvffanHpdlRrIL
ChainResidueDetails
S3GLU131-LEU152

site_idPS00641
Number of Residues18
DetailsCOMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PrfCYherlsvaGnCRmC
ChainResidueDetails
S1PRO38-CYS55

site_idPS00642
Number of Residues13
DetailsCOMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPiCDqGGeCdLQ
ChainResidueDetails
S1CYS105-GLN117

site_idPS00643
Number of Residues11
DetailsCOMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIqCtRCIrF
ChainResidueDetails
S1ARG152-PHE162

site_idPS00644
Number of Residues16
DetailsCOMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GAGAYICGEETALIES
ChainResidueDetails
V1GLY180-SER195

site_idPS00645
Number of Residues12
DetailsCOMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGqCtPCReG
ChainResidueDetails
V1GLU357-GLY368

site_idPS00667
Number of Residues16
DetailsCOMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GLLQpIaDAIKLFiKE
ChainResidueDetails
D1GLY44-GLU59

site_idPS00668
Number of Residues14
DetailsCOMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLTEGEseLVs.G
ChainResidueDetails
D1PRO197-GLY210

site_idPS01099
Number of Residues19
DetailsCOMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DklFTlieveCLGaCvnAP
ChainResidueDetails
V2ASP134-PRO152

site_idPS01150
Number of Residues17
DetailsCOMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GcDRIVPVDIYvPgCPP
ChainResidueDetails
S7GLY135-PRO151

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues220
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
D2PRO3-SER23
D2ASP274-MET294
D2LEU325-ILE345
D5MET366-LEU386
D5LEU413-GLY433
D5LEU457-ILE477
D5TYR485-SER505
D5GLY582-LEU602
D2HIS25-MET45
D2SER67-MET87
D2MET96-PRO116
D2ILE122-LEU142
D2ILE145-GLY165
D2ILE178-PRO198
D2MET200-MET220
D2ALA237-LEU257

site_idSWS_FT_FI2
Number of Residues8
DetailsBINDING: axial binding residue => ECO:0000250|UniProtKB:P00157
ChainResidueDetails
b1HIS83
b1HIS97
b1HIS182
b1HIS196
b2HIS83
b2HIS97
b2HIS182
b2HIS196

site_idSWS_FT_FI3
Number of Residues2
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:P00157
ChainResidueDetails
b1HIS201
b2HIS201

227561

PDB entries from 2024-11-20

PDB statisticsPDBj update infoContact PDBjnumon