Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0043066 | biological_process | negative regulation of apoptotic process |
| A | 0051726 | biological_process | regulation of cell cycle |
| B | 0005634 | cellular_component | nucleus |
| B | 0043066 | biological_process | negative regulation of apoptotic process |
| B | 0051726 | biological_process | regulation of cell cycle |
| C | 0005634 | cellular_component | nucleus |
| C | 0043066 | biological_process | negative regulation of apoptotic process |
| C | 0051726 | biological_process | regulation of cell cycle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue HRN A 201 |
| Chain | Residue |
| A | LYS51 |
| A | GLN72 |
| A | VAL93 |
| A | LEU99 |
| A | O4B202 |
| A | O4B204 |
| A | NA206 |
| A | HOH301 |
| A | HOH307 |
| A | MET54 |
| A | HIS55 |
| A | LEU57 |
| A | GLY58 |
| A | ILE61 |
| A | MET62 |
| A | TYR67 |
| A | GLN70 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue O4B A 202 |
| Chain | Residue |
| A | VAL93 |
| A | HRN201 |
| A | NA206 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue O4B A 203 |
| Chain | Residue |
| A | GLN27 |
| A | VAL28 |
| A | VAL50 |
| A | ARG104 |
| A | LEU107 |
| A | THR109 |
| C | GLN24 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue O4B A 204 |
| Chain | Residue |
| A | HIS55 |
| A | GLN59 |
| A | HRN201 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 205 |
| Chain | Residue |
| A | GLN44 |
| A | GLY45 |
| A | GLU46 |
| A | MET47 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue NA A 206 |
| Chain | Residue |
| A | HRN201 |
| A | O4B202 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 207 |
| Chain | Residue |
| A | LYS64 |
| A | GLN65 |
| A | O4B208 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue O4B A 208 |
| Chain | Residue |
| A | GLN65 |
| A | LEU66 |
| A | TYR76 |
| A | NA207 |
| B | VAL93 |
| B | TYR100 |
| B | HRN201 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | binding site for residue HRN C 201 |
| Chain | Residue |
| C | MET54 |
| C | HIS55 |
| C | GLY58 |
| C | ILE61 |
| C | MET62 |
| C | GLN72 |
| C | VAL93 |
| C | PRO96 |
| C | LEU99 |
| C | O4B206 |
| C | O4B207 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue O4B C 202 |
| Chain | Residue |
| B | GLN65 |
| B | GLY79 |
| B | GLU84 |
| C | LEU32 |
| C | PRO33 |
| C | LYS36 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue O4B C 203 |
| Chain | Residue |
| A | GLN24 |
| A | ILE25 |
| C | VAL28 |
| C | VAL50 |
| C | TYR100 |
| site_id | AD3 |
| Number of Residues | 8 |
| Details | binding site for residue O4B C 204 |
| Chain | Residue |
| B | ARG29 |
| B | LYS31 |
| B | LYS105 |
| B | LEU110 |
| C | GLY78 |
| C | GLY83 |
| C | GLY87 |
| C | GLN89 |
| site_id | AD4 |
| Number of Residues | 10 |
| Details | binding site for residue O4B C 205 |
| Chain | Residue |
| B | GLY78 |
| B | GLU84 |
| B | GLY87 |
| B | ARG88 |
| B | GLN89 |
| C | ARG29 |
| C | LYS31 |
| C | PRO33 |
| C | LYS105 |
| C | ASN106 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue O4B C 206 |
| Chain | Residue |
| C | VAL93 |
| C | HRN201 |
| C | NA211 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue O4B C 207 |
| Chain | Residue |
| C | HIS55 |
| C | GLN59 |
| C | MET62 |
| C | HRN201 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue O4B C 208 |
| Chain | Residue |
| B | LEU85 |
| B | LEU86 |
| B | LYS105 |
| C | GLU84 |
| C | LEU85 |
| C | LYS105 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 209 |
| Chain | Residue |
| C | LYS36 |
| C | TYR60 |
| C | LYS64 |
| C | LEU81 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 210 |
| Chain | Residue |
| B | ARG88 |
| C | GLY45 |
| C | GLU46 |
| C | MET47 |
| site_id | AE1 |
| Number of Residues | 1 |
| Details | binding site for residue NA C 211 |
| site_id | AE2 |
| Number of Residues | 15 |
| Details | binding site for residue HRN B 201 |
| Chain | Residue |
| A | O4B208 |
| B | MET54 |
| B | HIS55 |
| B | LEU57 |
| B | GLY58 |
| B | ILE61 |
| B | MET62 |
| B | TYR67 |
| B | GLN72 |
| B | PHE91 |
| B | VAL93 |
| B | PRO96 |
| B | LEU99 |
| B | TYR100 |
| B | O4B203 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue O4B B 202 |
| Chain | Residue |
| B | LYS36 |
| C | GLN65 |
| C | LEU66 |
| C | ASP68 |
| C | GLY79 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue O4B B 203 |
| Chain | Residue |
| B | HIS55 |
| B | GLN59 |
| B | MET62 |
| B | HRN201 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 204 |
| Chain | Residue |
| B | GLN89 |
| B | GLN89 |
| B | HOH302 |
| C | ARG29 |
| C | ARG29 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 205 |
| Chain | Residue |
| B | GLY45 |
| B | GLU46 |
| B | MET47 |
| C | ARG88 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 249 |
| Details | Domain: {"description":"SWIB/MDM2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01273","evidenceCode":"ECO:0000255"}]} |
