Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6Q9E

Complex III2 focused refinement from Ovine respiratory supercomplex I+III2

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
a1	0046872	molecular_function	metal ion binding
a2	0004222	molecular_function	metalloendopeptidase activity
a2	0006508	biological_process	proteolysis
a2	0046872	molecular_function	metal ion binding
a3	0046872	molecular_function	metal ion binding
a4	0004222	molecular_function	metalloendopeptidase activity
a4	0006508	biological_process	proteolysis
a4	0046872	molecular_function	metal ion binding
b1	0005743	cellular_component	mitochondrial inner membrane
b1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
b1	0008121	molecular_function	quinol-cytochrome-c reductase activity
b1	0009055	molecular_function	electron transfer activity
b1	0016020	cellular_component	membrane
b1	0016491	molecular_function	oxidoreductase activity
b1	0022904	biological_process	respiratory electron transport chain
b1	0045275	cellular_component	respiratory chain complex III
b1	0046872	molecular_function	metal ion binding
b1	1902600	biological_process	proton transmembrane transport
b2	0005743	cellular_component	mitochondrial inner membrane
b2	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
b2	0008121	molecular_function	quinol-cytochrome-c reductase activity
b2	0009055	molecular_function	electron transfer activity
b2	0016020	cellular_component	membrane
b2	0016491	molecular_function	oxidoreductase activity
b2	0022904	biological_process	respiratory electron transport chain
b2	0045275	cellular_component	respiratory chain complex III
b2	0046872	molecular_function	metal ion binding
b2	1902600	biological_process	proton transmembrane transport
c1	0009055	molecular_function	electron transfer activity
c1	0020037	molecular_function	heme binding
c2	0009055	molecular_function	electron transfer activity
c2	0020037	molecular_function	heme binding
d1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
d1	0045275	cellular_component	respiratory chain complex III
d2	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
d2	0045275	cellular_component	respiratory chain complex III
f1	0008121	molecular_function	quinol-cytochrome-c reductase activity
f1	0016020	cellular_component	membrane
f1	0051537	molecular_function	2 iron, 2 sulfur cluster binding
f2	0008121	molecular_function	quinol-cytochrome-c reductase activity
f2	0016020	cellular_component	membrane
f2	0051537	molecular_function	2 iron, 2 sulfur cluster binding
h1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
h2	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
i1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
i1	0045275	cellular_component	respiratory chain complex III
i2	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
i2	0045275	cellular_component	respiratory chain complex III
q1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
q1	0045275	cellular_component	respiratory chain complex III
q2	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
q2	0045275	cellular_component	respiratory chain complex III

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue HEM b1 401

Chain	Residue
b1	GLY48
b1	PHE183
b1	PRO186
b1	ALA52
b1	ARG80
b1	HIS83
b1	ALA87
b1	PHE90
b1	GLY130
b1	PRO134
b1	HIS182

site_id	AC2
Number of Residues	14
Details	binding site for residue HEM b1 402

Chain	Residue
b1	TRP31
b1	GLY34
b1	HIS97
b1	VAL98
b1	ARG100
b1	TRP113
b1	GLY116
b1	VAL117
b1	LEU119
b1	HIS196
b1	LEU200
b1	SER205
b1	ASN206
b1	U10407

site_id	AC3
Number of Residues	9
Details	binding site for residue 3PE b1 403

Chain	Residue
b1	TRP30
b1	PHE95
b1	MET96
b1	TYR103
b1	TYR104
b1	PHE276
b1	MET316
b1	TRP326
b1	CDL404

site_id	AC4
Number of Residues	8
Details	binding site for residue CDL b1 404

Chain	Residue
b1	SER28
b1	SER29
b1	TRP30
b1	3PE403
d1	GLN72
q1	VAL37
q1	ARG40
q1	CYS44

site_id	AC5
Number of Residues	4
Details	binding site for residue CDL b1 405

Chain	Residue
b1	ILE13
b1	LEU198
b2	ALA17
b2	LEU198

site_id	AC6
Number of Residues	8
Details	binding site for residue U10 b1 406

Chain	Residue
b1	GLY142
b1	VAL145
b1	ILE146
b1	LEU149
b1	PRO270
b1	PHE274
b1	TYR278
b1	LEU281

site_id	AC7
Number of Residues	8
Details	binding site for residue U10 b1 407

Chain	Residue
b1	PHE18
b1	LEU21
b1	TRP31
b1	SER35
b1	HIS201
b1	PHE220
b1	ASP228
b1	HEM402

site_id	AC8
Number of Residues	14
Details	binding site for residue HEC c1 501

Chain	Residue
c1	CYS37
c1	SER39
c1	CYS40
c1	HIS41
c1	ALA108
c1	PRO111
c1	ILE116
c1	ARG120
c1	TYR126
c1	LEU130
c1	PHE152
c1	GLY158
c1	MET159
c1	PRO162

site_id	AC9
Number of Residues	5
Details	binding site for residue 3PE c1 502

Chain	Residue
b1	TYR75
c1	MET203
c1	LYS206
c1	MET207
f1	GLN57

site_id	AD1
Number of Residues	12
Details	binding site for residue CDL c1 503

Chain	Residue
b1	SER29
b1	ASN32
b1	GLY231
c1	TYR219
c1	LYS222
c1	ARG223
c1	LYS230
q1	TYR29
q1	PHE30
q1	GLY33
q1	VAL37
q1	ARG40

site_id	AD2
Number of Residues	7
Details	binding site for residue FES f1 501

Chain	Residue
f1	SER163
f1	CYS139
f1	HIS141
f1	LEU142
f1	CYS144
f1	CYS158
f1	HIS161

site_id	AD3
Number of Residues	11
Details	binding site for residue HEM b2 401

Chain	Residue
b2	GLY48
b2	VAL66
b2	ARG80
b2	HIS83
b2	ALA87
b2	PHE90
b2	GLY130
b2	PRO134
b2	HIS182
b2	PHE183
b2	PRO186

site_id	AD4
Number of Residues	12
Details	binding site for residue HEM b2 402

Chain	Residue
b2	TRP31
b2	HIS97
b2	ARG100
b2	SER106
b2	TRP113
b2	GLY116
b2	VAL117
b2	LEU119
b2	HIS196
b2	LEU200
b2	ASN206
b2	U10405

site_id	AD5
Number of Residues	11
Details	binding site for residue 3PE b2 403

Chain	Residue
b2	TRP30
b2	PHE95
b2	MET96
b2	TYR103
b2	MET316
b2	GLN322
b2	TRP326
b2	LEU332
b2	TYR358
b2	CDL404
q2	VAL48

site_id	AD6
Number of Residues	8
Details	binding site for residue CDL b2 404

Chain	Residue
b2	SER28
b2	SER29
b2	TRP30
b2	3PE403
c2	CDL502
d2	GLN72
q2	ARG40
q2	THR41

site_id	AD7
Number of Residues	9
Details	binding site for residue U10 b2 405

Chain	Residue
b2	PHE18
b2	LEU21
b2	TRP31
b2	SER35
b2	LEU197
b2	HIS201
b2	SER205
b2	PHE220
b2	HEM402

site_id	AD8
Number of Residues	11
Details	binding site for residue CDL c2 502

Chain	Residue
b2	SER29
b2	ASN32
b2	CDL404
c2	TYR219
c2	LYS222
c2	ARG223
c2	LYS230
q2	TYR29
q2	ASN36
q2	VAL37
q2	ARG40

site_id	AD9
Number of Residues	6
Details	binding site for residue 3PE f2 201

Chain	Residue
c2	HIS199
c2	MET203
c2	LYS206
f2	ASN53
f2	GLN57
i2	ASP36

site_id	AE1
Number of Residues	6
Details	binding site for residue FES f2 202

Chain	Residue
f2	CYS139
f2	HIS141
f2	LEU142
f2	CYS158
f2	HIS161
f2	SER163

site_id	AE2
Number of Residues	14
Details	binding site for Di-peptide HEC c2 501 and CYS c2 40

Chain	Residue
c2	VAL36
c2	CYS37
c2	SER39
c2	HIS41
c2	ASN105
c2	ALA108
c2	PRO110
c2	ILE116
c2	ARG120
c2	TYR126
c2	LEU130
c2	PHE152
c2	GLY158
c2	MET159

site_id	AE3
Number of Residues	16
Details	binding site for Di-peptide HEC c2 501 and CYS c2 37

Chain	Residue
c2	TYR33
c2	VAL36
c2	SER38
c2	SER39
c2	CYS40
c2	HIS41
c2	ASN105
c2	ALA108
c2	PRO110
c2	ILE116
c2	ARG120
c2	TYR126
c2	LEU130
c2	PHE152
c2	GLY158
c2	MET159

Functional Information from PROSITE/UniProt

site_id	PS00143
Number of Residues	24
Details	INSULINASE Insulinase family, zinc-binding region signature. GsryenfnnlGtSHLLRLAsSlTT

Chain	Residue	Details
a2	GLY54-THR77

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	322
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"UniProtKB","id":"P00157","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"UniProtKB","id":"P00157","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P00157","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)