6Q9D
CI Peripheral Arm focused refinement from Ovine respiratory SC I+III2
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A5 | 0022904 | biological_process | respiratory electron transport chain |
| A6 | 0005739 | cellular_component | mitochondrion |
| A6 | 0005743 | cellular_component | mitochondrial inner membrane |
| A6 | 0005747 | cellular_component | mitochondrial respiratory chain complex I |
| A6 | 0006979 | biological_process | response to oxidative stress |
| A6 | 0016020 | cellular_component | membrane |
| A6 | 0031966 | cellular_component | mitochondrial membrane |
| A6 | 0032981 | biological_process | mitochondrial respiratory chain complex I assembly |
| A6 | 0070469 | cellular_component | respirasome |
| A7 | 0005743 | cellular_component | mitochondrial inner membrane |
| A7 | 0005747 | cellular_component | mitochondrial respiratory chain complex I |
| A7 | 0006120 | biological_process | mitochondrial electron transport, NADH to ubiquinone |
| A7 | 0016020 | cellular_component | membrane |
| A7 | 0042773 | biological_process | ATP synthesis coupled electron transport |
| AA | 0006633 | biological_process | fatty acid biosynthetic process |
| AL | 0016020 | cellular_component | membrane |
| AL | 0032981 | biological_process | mitochondrial respiratory chain complex I assembly |
| S1 | 0008137 | molecular_function | NADH dehydrogenase (ubiquinone) activity |
| S1 | 0016020 | cellular_component | membrane |
| S1 | 0016491 | molecular_function | oxidoreductase activity |
| S1 | 0016651 | molecular_function | oxidoreductase activity, acting on NAD(P)H |
| S1 | 0042773 | biological_process | ATP synthesis coupled electron transport |
| S1 | 0051536 | molecular_function | iron-sulfur cluster binding |
| S2 | 0016651 | molecular_function | oxidoreductase activity, acting on NAD(P)H |
| S2 | 0048038 | molecular_function | quinone binding |
| S2 | 0051287 | molecular_function | NAD binding |
| S3 | 0008137 | molecular_function | NADH dehydrogenase (ubiquinone) activity |
| S3 | 0016651 | molecular_function | oxidoreductase activity, acting on NAD(P)H |
| S4 | 0022900 | biological_process | electron transport chain |
| S6 | 0005747 | cellular_component | mitochondrial respiratory chain complex I |
| S6 | 0006120 | biological_process | mitochondrial electron transport, NADH to ubiquinone |
| S7 | 0008137 | molecular_function | NADH dehydrogenase (ubiquinone) activity |
| S7 | 0048038 | molecular_function | quinone binding |
| S7 | 0051536 | molecular_function | iron-sulfur cluster binding |
| S7 | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| S8 | 0016020 | cellular_component | membrane |
| S8 | 0016651 | molecular_function | oxidoreductase activity, acting on NAD(P)H |
| S8 | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| V1 | 0003954 | molecular_function | NADH dehydrogenase activity |
| V1 | 0005739 | cellular_component | mitochondrion |
| V1 | 0005743 | cellular_component | mitochondrial inner membrane |
| V1 | 0005747 | cellular_component | mitochondrial respiratory chain complex I |
| V1 | 0006120 | biological_process | mitochondrial electron transport, NADH to ubiquinone |
| V1 | 0008137 | molecular_function | NADH dehydrogenase (ubiquinone) activity |
| V1 | 0010181 | molecular_function | FMN binding |
| V1 | 0016020 | cellular_component | membrane |
| V1 | 0045271 | cellular_component | respiratory chain complex I |
| V1 | 0046872 | molecular_function | metal ion binding |
| V1 | 0051287 | molecular_function | NAD binding |
| V1 | 0051536 | molecular_function | iron-sulfur cluster binding |
| V1 | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| V1 | 0055085 | biological_process | transmembrane transport |
| V1 | 0070469 | cellular_component | respirasome |
| V2 | 0016491 | molecular_function | oxidoreductase activity |
| V3 | 0005739 | cellular_component | mitochondrion |
| V3 | 0005747 | cellular_component | mitochondrial respiratory chain complex I |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue SF4 V1 500 |
| Chain | Residue |
| V1 | PRO203 |
| V1 | CYS405 |
| V1 | SER358 |
| V1 | CYS359 |
| V1 | GLY360 |
| V1 | GLN361 |
| V1 | CYS362 |
| V1 | CYS365 |
| V1 | THR403 |
| V1 | ILE404 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue FMN V1 501 |
| Chain | Residue |
| V1 | GLY67 |
| V1 | ARG68 |
| V1 | GLY69 |
| V1 | ALA71 |
| V1 | PHE73 |
| V1 | LYS78 |
| V1 | ASN96 |
| V1 | ASP98 |
| V1 | TYR184 |
| V1 | GLY187 |
| V1 | GLU188 |
| V1 | VAL222 |
| V1 | ASN224 |
| V1 | THR227 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue FES V2 300 |
| Chain | Residue |
| V2 | CYS103 |
| V2 | THR105 |
| V2 | CYS108 |
| V2 | CYS144 |
| V2 | LEU145 |
| V2 | GLY146 |
| V2 | ALA147 |
| V2 | CYS148 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue SF4 S1 801 |
| Chain | Residue |
| S1 | HIS101 |
| S1 | ASP104 |
| S1 | CYS105 |
| S1 | CYS108 |
| S1 | CYS114 |
| S1 | GLN117 |
| S1 | VAL205 |
| S1 | GLY206 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue SF4 S1 802 |
| Chain | Residue |
| S1 | CYS153 |
| S1 | ILE154 |
| S1 | CYS156 |
| S1 | THR157 |
| S1 | CYS159 |
| S1 | CYS203 |
| S1 | VAL205 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue FES S1 803 |
| Chain | Residue |
| S1 | CYS41 |
| S1 | TYR42 |
| S1 | GLY50 |
| S1 | CYS52 |
| S1 | ARG53 |
| S1 | CYS55 |
| S1 | CYS69 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue SF4 S7 300 |
| Chain | Residue |
| S2 | ARG105 |
| S7 | ALA53 |
| S7 | CYS54 |
| S7 | CYS55 |
| S7 | GLY90 |
| S7 | GLY117 |
| S7 | SER118 |
| S7 | CYS119 |
| S7 | CYS149 |
| S7 | PRO150 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | binding site for residue SF4 S8 201 |
| Chain | Residue |
| S8 | CYS87 |
| S8 | PRO88 |
| S8 | ILE92 |
| S8 | CYS116 |
| S8 | ILE117 |
| S8 | TYR118 |
| S8 | CYS119 |
| S8 | GLY120 |
| S8 | CYS122 |
| S8 | GLU133 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | binding site for residue SF4 S8 202 |
| Chain | Residue |
| S8 | CYS77 |
| S8 | ILE78 |
| S8 | ALA79 |
| S8 | CYS80 |
| S8 | LYS81 |
| S8 | CYS83 |
| S8 | CYS126 |
| S8 | ILE131 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue ZN S6 300 |
| Chain | Residue |
| S6 | CYS59 |
| S6 | HIS68 |
| S6 | VAL71 |
| S6 | CYS84 |
| S6 | CYS87 |
| site_id | AD2 |
| Number of Residues | 15 |
| Details | binding site for residue NDP A9 401 |
| Chain | Residue |
| A9 | ALA169 |
| A9 | ILE171 |
| A9 | ARG177 |
| A9 | THR27 |
| A9 | GLY28 |
| A9 | PHE29 |
| A9 | LEU30 |
| A9 | ARG50 |
| A9 | VAL95 |
| A9 | GLY96 |
| A9 | ARG97 |
| A9 | ILE132 |
| A9 | HIS134 |
| A9 | TYR145 |
| A9 | LYS149 |
| site_id | AD3 |
| Number of Residues | 10 |
| Details | binding site for residue ZMP AA 101 |
| Chain | Residue |
| A6 | LYS28 |
| A6 | ARG32 |
| A6 | TRP38 |
| A6 | VAL62 |
| A6 | PHE66 |
| A6 | ASN69 |
| A6 | ALA70 |
| A6 | LEU81 |
| AA | ASP43 |
| AA | SER44 |
Functional Information from PROSITE/UniProt
| site_id | PS00641 |
| Number of Residues | 18 |
| Details | COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PrfCYherlsvaGnCRmC |
| Chain | Residue | Details |
| S1 | PRO38-CYS55 |
| site_id | PS00642 |
| Number of Residues | 13 |
| Details | COMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPiCDqGGeCdLQ |
| Chain | Residue | Details |
| S1 | CYS105-GLN117 |
| site_id | PS00643 |
| Number of Residues | 11 |
| Details | COMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIqCtRCIrF |
| Chain | Residue | Details |
| S1 | ARG152-PHE162 |
| site_id | PS00198 |
| Number of Residues | 12 |
| Details | 4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaVCP |
| Chain | Residue | Details |
| S8 | CYS77-PRO88 | |
| S8 | CYS116-PRO127 |
| site_id | PS01099 |
| Number of Residues | 19 |
| Details | COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DklFTlieveCLGaCvnAP |
| Chain | Residue | Details |
| V2 | ASP134-PRO152 |
| site_id | PS01150 |
| Number of Residues | 17 |
| Details | COMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GcDRIVPVDIYvPgCPP |
| Chain | Residue | Details |
| S7 | GLY135-PRO151 |
| site_id | PS00542 |
| Number of Residues | 22 |
| Details | COMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREiwDMFgvffanHpdlRrIL |
| Chain | Residue | Details |
| S3 | GLU131-LEU152 |
| site_id | PS00644 |
| Number of Residues | 16 |
| Details | COMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GAGAYICGEETALIES |
| Chain | Residue | Details |
| V1 | GLY180-SER195 |
| site_id | PS00645 |
| Number of Residues | 12 |
| Details | COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGqCtPCReG |
| Chain | Residue | Details |
| V1 | GLU357-GLY368 |
| site_id | PS00012 |
| Number of Residues | 16 |
| Details | PHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGLDSLDQVEIIMAM |
| Chain | Residue | Details |
| AA | ASP39-MET54 |
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DIDAEKLMCpqEI |
| Chain | Residue | Details |
| AA | ASP64-ILE76 |
| site_id | PS00535 |
| Number of Residues | 12 |
| Details | COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLiEyK |
| Chain | Residue | Details |
| S2 | LEU83-LYS94 |
