Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6Q45

F1-ATPase from Fusobacterium nucleatum

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0005886	cellular_component	plasma membrane
A	0006754	biological_process	ATP biosynthetic process
A	0015986	biological_process	proton motive force-driven ATP synthesis
A	0032559	molecular_function	adenyl ribonucleotide binding
A	0043531	molecular_function	ADP binding
A	0045259	cellular_component	proton-transporting ATP synthase complex
A	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
A	0046034	biological_process	ATP metabolic process
A	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
A	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
A	1902600	biological_process	proton transmembrane transport
B	0005524	molecular_function	ATP binding
B	0005886	cellular_component	plasma membrane
B	0006754	biological_process	ATP biosynthetic process
B	0015986	biological_process	proton motive force-driven ATP synthesis
B	0032559	molecular_function	adenyl ribonucleotide binding
B	0043531	molecular_function	ADP binding
B	0045259	cellular_component	proton-transporting ATP synthase complex
B	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
B	0046034	biological_process	ATP metabolic process
B	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
B	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
B	1902600	biological_process	proton transmembrane transport
C	0005524	molecular_function	ATP binding
C	0005886	cellular_component	plasma membrane
C	0006754	biological_process	ATP biosynthetic process
C	0015986	biological_process	proton motive force-driven ATP synthesis
C	0032559	molecular_function	adenyl ribonucleotide binding
C	0043531	molecular_function	ADP binding
C	0045259	cellular_component	proton-transporting ATP synthase complex
C	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
C	0046034	biological_process	ATP metabolic process
C	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
C	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
C	1902600	biological_process	proton transmembrane transport
D	0005524	molecular_function	ATP binding
D	0005886	cellular_component	plasma membrane
D	0006754	biological_process	ATP biosynthetic process
D	0015986	biological_process	proton motive force-driven ATP synthesis
D	0016887	molecular_function	ATP hydrolysis activity
D	0045259	cellular_component	proton-transporting ATP synthase complex
D	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
D	0046034	biological_process	ATP metabolic process
D	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
D	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
D	1902600	biological_process	proton transmembrane transport
E	0005524	molecular_function	ATP binding
E	0005886	cellular_component	plasma membrane
E	0006754	biological_process	ATP biosynthetic process
E	0015986	biological_process	proton motive force-driven ATP synthesis
E	0016887	molecular_function	ATP hydrolysis activity
E	0045259	cellular_component	proton-transporting ATP synthase complex
E	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
E	0046034	biological_process	ATP metabolic process
E	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
E	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
E	1902600	biological_process	proton transmembrane transport
F	0005524	molecular_function	ATP binding
F	0005886	cellular_component	plasma membrane
F	0006754	biological_process	ATP biosynthetic process
F	0015986	biological_process	proton motive force-driven ATP synthesis
F	0016887	molecular_function	ATP hydrolysis activity
F	0045259	cellular_component	proton-transporting ATP synthase complex
F	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
F	0046034	biological_process	ATP metabolic process
F	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
F	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
F	1902600	biological_process	proton transmembrane transport
G	0005524	molecular_function	ATP binding
G	0005886	cellular_component	plasma membrane
G	0006754	biological_process	ATP biosynthetic process
G	0015986	biological_process	proton motive force-driven ATP synthesis
G	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
G	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
G	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
G	1902600	biological_process	proton transmembrane transport
H	0005524	molecular_function	ATP binding
H	0005886	cellular_component	plasma membrane
H	0006754	biological_process	ATP biosynthetic process
H	0015986	biological_process	proton motive force-driven ATP synthesis
H	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
H	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
H	1902600	biological_process	proton transmembrane transport
I	0005524	molecular_function	ATP binding
I	0005886	cellular_component	plasma membrane
I	0006754	biological_process	ATP biosynthetic process
I	0015986	biological_process	proton motive force-driven ATP synthesis
I	0032559	molecular_function	adenyl ribonucleotide binding
I	0043531	molecular_function	ADP binding
I	0045259	cellular_component	proton-transporting ATP synthase complex
I	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
I	0046034	biological_process	ATP metabolic process
I	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
I	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
I	1902600	biological_process	proton transmembrane transport
J	0005524	molecular_function	ATP binding
J	0005886	cellular_component	plasma membrane
J	0006754	biological_process	ATP biosynthetic process
J	0015986	biological_process	proton motive force-driven ATP synthesis
J	0032559	molecular_function	adenyl ribonucleotide binding
J	0043531	molecular_function	ADP binding
J	0045259	cellular_component	proton-transporting ATP synthase complex
J	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
J	0046034	biological_process	ATP metabolic process
J	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
J	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
J	1902600	biological_process	proton transmembrane transport
K	0005524	molecular_function	ATP binding
K	0005886	cellular_component	plasma membrane
K	0006754	biological_process	ATP biosynthetic process
K	0015986	biological_process	proton motive force-driven ATP synthesis
K	0032559	molecular_function	adenyl ribonucleotide binding
K	0043531	molecular_function	ADP binding
K	0045259	cellular_component	proton-transporting ATP synthase complex
K	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
K	0046034	biological_process	ATP metabolic process
K	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
K	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
K	1902600	biological_process	proton transmembrane transport
L	0005524	molecular_function	ATP binding
L	0005886	cellular_component	plasma membrane
L	0006754	biological_process	ATP biosynthetic process
L	0015986	biological_process	proton motive force-driven ATP synthesis
L	0016887	molecular_function	ATP hydrolysis activity
L	0045259	cellular_component	proton-transporting ATP synthase complex
L	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
L	0046034	biological_process	ATP metabolic process
L	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
L	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
L	1902600	biological_process	proton transmembrane transport
M	0005524	molecular_function	ATP binding
M	0005886	cellular_component	plasma membrane
M	0006754	biological_process	ATP biosynthetic process
M	0015986	biological_process	proton motive force-driven ATP synthesis
M	0016887	molecular_function	ATP hydrolysis activity
M	0045259	cellular_component	proton-transporting ATP synthase complex
M	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
M	0046034	biological_process	ATP metabolic process
M	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
M	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
M	1902600	biological_process	proton transmembrane transport
N	0005524	molecular_function	ATP binding
N	0005886	cellular_component	plasma membrane
N	0006754	biological_process	ATP biosynthetic process
N	0015986	biological_process	proton motive force-driven ATP synthesis
N	0016887	molecular_function	ATP hydrolysis activity
N	0045259	cellular_component	proton-transporting ATP synthase complex
N	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
N	0046034	biological_process	ATP metabolic process
N	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
N	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
N	1902600	biological_process	proton transmembrane transport
O	0005524	molecular_function	ATP binding
O	0005886	cellular_component	plasma membrane
O	0006754	biological_process	ATP biosynthetic process
O	0015986	biological_process	proton motive force-driven ATP synthesis
O	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
O	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
O	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
O	1902600	biological_process	proton transmembrane transport
P	0005524	molecular_function	ATP binding
P	0005886	cellular_component	plasma membrane
P	0006754	biological_process	ATP biosynthetic process
P	0015986	biological_process	proton motive force-driven ATP synthesis
P	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
P	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
P	1902600	biological_process	proton transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue ATP A 600

Chain	Residue
A	ARG171
A	GLN422
A	GLN424
A	MG601
A	HOH701
A	HOH702
A	GLN172
A	THR173
A	GLY174
A	LYS175
A	THR176
A	ALA177
A	PHE349
A	ARG354

site_id	AC2
Number of Residues	5
Details	binding site for residue MG A 601

Chain	Residue
A	THR176
A	ATP600
A	HOH701
A	HOH702
A	HOH703

site_id	AC3
Number of Residues	15
Details	binding site for residue ATP B 600

Chain	Residue
B	GLN172
B	THR173
B	GLY174
B	LYS175
B	THR176
B	ALA177
B	GLU320
B	PHE349
B	ARG354
B	PRO355
B	GLN422
B	GLN424
B	MG601
B	HOH702
B	HOH703

site_id	AC4
Number of Residues	5
Details	binding site for residue MG B 601

Chain	Residue
B	THR176
B	ATP600
B	HOH701
B	HOH702
B	HOH703

site_id	AC5
Number of Residues	15
Details	binding site for residue ATP C 600

Chain	Residue
C	ARG171
C	GLN172
C	THR173
C	GLY174
C	LYS175
C	THR176
C	ALA177
C	PHE349
C	ARG354
C	GLN422
C	PRO423
C	GLN424
C	MG601
C	HOH702
C	HOH703

site_id	AC6
Number of Residues	5
Details	binding site for residue MG C 601

Chain	Residue
C	THR176
C	ATP600
C	HOH701
C	HOH702
C	HOH703

site_id	AC7
Number of Residues	16
Details	binding site for residue ADP D 600

Chain	Residue
C	SER364
C	ARG365
D	GLY150
D	GLY152
D	VAL153
D	GLY154
D	LYS155
D	THR156
D	VAL157
D	TYR332
D	PHE405
D	ALA408
D	PHE411
D	MG601
D	HOH701
D	HOH703

site_id	AC8
Number of Residues	7
Details	binding site for residue MG D 601

Chain	Residue
D	THR156
D	ARG182
D	ADP600
D	HOH701
D	HOH702
D	HOH703
D	HOH704

site_id	AC9
Number of Residues	13
Details	binding site for residue ADP F 600

Chain	Residue
B	ARG365
F	GLY150
F	GLY152
F	VAL153
F	GLY154
F	LYS155
F	THR156
F	VAL157
F	TYR332
F	PHE405
F	MG601
F	HOH701
F	HOH703

site_id	AD1
Number of Residues	7
Details	binding site for residue MG F 601

Chain	Residue
F	HOH702
F	HOH703
F	HOH704
F	THR156
F	ARG182
F	ADP600
F	HOH701

site_id	AD2
Number of Residues	15
Details	binding site for residue ATP I 600

Chain	Residue
I	ARG171
I	GLN172
I	THR173
I	GLY174
I	LYS175
I	THR176
I	ALA177
I	PHE349
I	ARG354
I	GLN422
I	GLN424
I	MG601
I	HOH701
I	HOH702
L	LYS343

site_id	AD3
Number of Residues	5
Details	binding site for residue MG I 601

Chain	Residue
I	THR176
I	ATP600
I	HOH701
I	HOH702
I	HOH703

site_id	AD4
Number of Residues	14
Details	binding site for residue ATP J 600

Chain	Residue
J	GLN172
J	THR173
J	GLY174
J	LYS175
J	THR176
J	ALA177
J	GLU320
J	PHE349
J	ARG354
J	GLN422
J	GLN424
J	MG601
J	HOH701
J	HOH703

site_id	AD5
Number of Residues	5
Details	binding site for residue MG J 601

Chain	Residue
J	THR176
J	ATP600
J	HOH701
J	HOH702
J	HOH703

site_id	AD6
Number of Residues	14
Details	binding site for residue ATP K 600

Chain	Residue
K	GLN172
K	THR173
K	GLY174
K	LYS175
K	THR176
K	ALA177
K	GLU320
K	PHE349
K	ARG354
K	GLN422
K	GLN424
K	MG601
K	HOH701
K	HOH702

site_id	AD7
Number of Residues	5
Details	binding site for residue MG K 601

Chain	Residue
K	THR176
K	ATP600
K	HOH701
K	HOH702
K	HOH703

site_id	AD8
Number of Residues	15
Details	binding site for residue ADP L 600

Chain	Residue
K	SER364
K	ARG365
L	GLY150
L	GLY152
L	VAL153
L	GLY154
L	LYS155
L	THR156
L	VAL157
L	TYR332
L	PHE405
L	PHE411
L	MG601
L	HOH701
L	HOH702

site_id	AD9
Number of Residues	7
Details	binding site for residue MG L 601

Chain	Residue
L	THR156
L	ARG182
L	ADP600
L	HOH701
L	HOH702
L	HOH703
L	HOH704

site_id	AE1
Number of Residues	13
Details	binding site for residue ADP N 600

Chain	Residue
J	ARG365
N	GLY150
N	GLY152
N	VAL153
N	GLY154
N	LYS155
N	THR156
N	VAL157
N	TYR332
N	PHE405
N	MG601
N	HOH701
N	HOH702

site_id	AE2
Number of Residues	7
Details	binding site for residue MG N 601

Chain	Residue
N	THR156
N	ARG182
N	ADP600
N	HOH701
N	HOH702
N	HOH703
N	HOH704

Functional Information from PROSITE/UniProt

site_id	PS00152
Number of Residues	10
Details	ATPASE_ALPHA_BETA ATP synthase alpha and beta subunits signature. PAVDPLDSTS

Chain	Residue	Details
D	PRO333-SER342
A	PRO355-SER364

site_id	PS00153
Number of Residues	14
Details	ATPASE_GAMMA ATP synthase gamma subunit signature. ITqEitEivgGAsA

Chain	Residue	Details
G	ILE268-ALA281

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_01347

Chain	Residue	Details
D	GLY149
E	GLY149
F	GLY149
L	GLY149
M	GLY149
N	GLY149

site_id	SWS_FT_FI2
Number of Residues	6
Details	SITE: Required for activity => ECO:0000255\|HAMAP-Rule:MF_01346

Chain	Residue	Details
A	SER362
B	SER362
C	SER362
I	SER362
J	SER362
K	SER362

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)