6Q2D

Crystal structure of Methanobrevibacter smithii Dph2 in complex with Methanobrevibacter smithii elongation factor 2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016740	molecular_function	transferase activity
A	0017183	biological_process	protein histidyl modification to diphthamide
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding
A	0090560	molecular_function	2-(3-amino-3-carboxypropyl)histidine synthase activity
B	0016740	molecular_function	transferase activity
B	0017183	biological_process	protein histidyl modification to diphthamide
B	0046872	molecular_function	metal ion binding
B	0051536	molecular_function	iron-sulfur cluster binding
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
B	0090560	molecular_function	2-(3-amino-3-carboxypropyl)histidine synthase activity
C	0000166	molecular_function	nucleotide binding
C	0003746	molecular_function	translation elongation factor activity
C	0003924	molecular_function	GTPase activity
C	0005525	molecular_function	GTP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006412	biological_process	translation
C	0006414	biological_process	translational elongation
C	1990904	cellular_component	ribonucleoprotein complex
F	0000166	molecular_function	nucleotide binding
F	0003746	molecular_function	translation elongation factor activity
F	0003924	molecular_function	GTPase activity
F	0005525	molecular_function	GTP binding
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006412	biological_process	translation
F	0006414	biological_process	translational elongation
F	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue SF4 A 401

Chain	Residue
A	PHE58
A	GLY59
A	CYS61
A	CYS161
A	GLN242
A	CYS289
A	ILE327

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site_id	AC2
Number of Residues	6
Details	binding site for residue SF4 B 401

Chain	Residue
B	CYS161
B	CYS289
B	ARG291
B	ILE327
B	CYS61
B	GLY160

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Functional Information from PROSITE/UniProt

site_id	PS00301
Number of Residues	16
Details	G_TR_1 Translational (tr)-type guanine nucleotide-binding (G) domain signature. DFdeqEQaRGITIdaA

Chain	Residue	Details
C	ASP60-ALA75

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