6Q1Y

Crystal Structure of Enoyl-[acyl-carrier-protein] reductase from Mycobacterium avium with bound NAD

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004318	molecular_function	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A	0006633	biological_process	fatty acid biosynthetic process
A	0050343	molecular_function	trans-2-enoyl-CoA reductase (NADH) activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	38
Details	binding site for residue NAD A 301

Chain	Residue
A	GLY14
A	SER94
A	ILE95
A	GLY96
A	ILE122
A	MET147
A	ASP148
A	PHE149
A	LYS165
A	ALA191
A	GLY192
A	ILE15
A	PRO193
A	ILE194
A	THR196
A	HOH435
A	HOH448
A	HOH452
A	HOH456
A	HOH462
A	HOH465
A	HOH489
A	ILE16
A	HOH523
A	HOH527
A	HOH549
A	HOH565
A	HOH570
A	HOH584
A	HOH595
A	HOH614
A	HOH635
A	SER20
A	ILE21
A	PHE41
A	LEU63
A	ASP64
A	VAL65

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site_id	AC2
Number of Residues	5
Details	binding site for residue ACT A 302

Chain	Residue
A	ASP52
A	LEU54
A	GLU56
A	LYS57
A	HOH406

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site_id	AC3
Number of Residues	6
Details	binding site for residue PEG A 303

Chain	Residue
A	PHE109
A	ASP110
A	TYR125
A	LYS132
A	HOH447
A	HOH536

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site_id	AC4
Number of Residues	3
Details	binding site for residue EDO A 304

Chain	Residue
A	VAL206
A	GLY208
A	HOH414

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site_id	AC5
Number of Residues	6
Details	binding site for residue PG4 A 305

Chain	Residue
A	LEU197
A	GLY204
A	VAL206
A	HOH408
A	HOH449
A	HOH576

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site_id	AC6
Number of Residues	6
Details	binding site for residue PG4 A 306

Chain	Residue
A	LYS233
A	LYS233
A	ASP234
A	ASP234
A	HOH427
A	HOH427

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