6PTV

Crystal structure of a DnaN sliding clamp (DNA polymerase III subunit beta) from Rickettsia rickettsii bound to griselimycin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005737	cellular_component	cytoplasm
A	0006260	biological_process	DNA replication
A	0006271	biological_process	DNA strand elongation involved in DNA replication
A	0008408	molecular_function	3'-5' exonuclease activity
A	0009360	cellular_component	DNA polymerase III complex
A	0071897	biological_process	DNA biosynthetic process
B	0003677	molecular_function	DNA binding
B	0003887	molecular_function	DNA-directed DNA polymerase activity
B	0005737	cellular_component	cytoplasm
B	0006260	biological_process	DNA replication
B	0006271	biological_process	DNA strand elongation involved in DNA replication
B	0008408	molecular_function	3'-5' exonuclease activity
B	0009360	cellular_component	DNA polymerase III complex
B	0071897	biological_process	DNA biosynthetic process
C	0003677	molecular_function	DNA binding
C	0003887	molecular_function	DNA-directed DNA polymerase activity
C	0005737	cellular_component	cytoplasm
C	0006260	biological_process	DNA replication
C	0006271	biological_process	DNA strand elongation involved in DNA replication
C	0008408	molecular_function	3'-5' exonuclease activity
C	0009360	cellular_component	DNA polymerase III complex
C	0071897	biological_process	DNA biosynthetic process
D	0003677	molecular_function	DNA binding
D	0003887	molecular_function	DNA-directed DNA polymerase activity
D	0005737	cellular_component	cytoplasm
D	0006260	biological_process	DNA replication
D	0006271	biological_process	DNA strand elongation involved in DNA replication
D	0008408	molecular_function	3'-5' exonuclease activity
D	0009360	cellular_component	DNA polymerase III complex
D	0071897	biological_process	DNA biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue MPD A 401

Chain	Residue
A	THR172
A	GLY174
A	PHE251
A	LEU375

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site_id	AC2
Number of Residues	3
Details	binding site for residue MPD D 401

Chain	Residue
D	THR172
D	GLY174
D	PHE251

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site_id	AC3
Number of Residues	19
Details	binding site for ACE-MVA-MP8-NZC-LEU-MP8-LEU-MVA-PRO-MLU-GLY chain X

Chain	Residue
B	GLY174
B	HIS175
B	PHE251
B	SER357
B	LEU375
B	PRO376
B	VAL377
B	LYS378
B	HOH564
B	HOH598
D	ASN49
D	MET50
D	PRO117
D	ASP120
D	GLU150
D	TYR153
X	HOH101
B	ARG152
B	THR172

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site_id	AC4
Number of Residues	21
Details	binding site for ACE-MVA-MP8-NZC-LEU-MP8-LEU-MVA-PRO-MLU-GLY chain Y

Chain	Residue
A	ASN49
A	MET50
A	PRO117
A	ASP120
A	GLU150
A	TYR153
C	ARG152
C	THR172
C	GLY174
C	HIS175
C	PRO246
C	PHE251
C	SER357
C	LEU375
C	PRO376
C	VAL377
C	LYS378
C	HOH544
Y	HOH101
Y	HOH102
Y	HOH103

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