6PPZ
Crystal structure of NeuB, an N-acetylneuraminate synthase from Neisseria meningitidis, in complex with manganese, inorganic phosphate, and N-acetylmannosamine (NeuB.Mn2+.Pi.ManNAc)
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0016051 | biological_process | carbohydrate biosynthetic process |
A | 0016740 | molecular_function | transferase activity |
A | 0046872 | molecular_function | metal ion binding |
A | 0047444 | molecular_function | N-acylneuraminate-9-phosphate synthase activity |
A | 0050462 | molecular_function | N-acetylneuraminate synthase activity |
A | 0070085 | biological_process | glycosylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 13 |
Details | binding site for residue MN9 A 401 |
Chain | Residue |
A | GLN55 |
A | PO4403 |
A | HOH501 |
A | HOH535 |
A | HOH538 |
A | ASN74 |
A | PHE112 |
A | TYR186 |
A | HIS236 |
A | ASP247 |
A | ALA289 |
A | ARG314 |
A | MN402 |
site_id | AC2 |
Number of Residues | 6 |
Details | binding site for residue MN A 402 |
Chain | Residue |
A | GLU25 |
A | HIS215 |
A | GLU234 |
A | HIS236 |
A | MN9401 |
A | PO4403 |
site_id | AC3 |
Number of Residues | 13 |
Details | binding site for residue PO4 A 403 |
Chain | Residue |
A | LYS129 |
A | GLY131 |
A | SER132 |
A | SER154 |
A | CYS182 |
A | ASN184 |
A | TYR186 |
A | SER213 |
A | HIS215 |
A | GLU234 |
A | MN9401 |
A | MN402 |
A | HOH501 |