6PPZ
Crystal structure of NeuB, an N-acetylneuraminate synthase from Neisseria meningitidis, in complex with manganese, inorganic phosphate, and N-acetylmannosamine (NeuB.Mn2+.Pi.ManNAc)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016051 | biological_process | carbohydrate biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047444 | molecular_function | N-acylneuraminate-9-phosphate synthase activity |
| A | 0050462 | molecular_function | N-acetylneuraminate synthase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue MN9 A 401 |
| Chain | Residue |
| A | GLN55 |
| A | PO4403 |
| A | HOH501 |
| A | HOH535 |
| A | HOH538 |
| A | ASN74 |
| A | PHE112 |
| A | TYR186 |
| A | HIS236 |
| A | ASP247 |
| A | ALA289 |
| A | ARG314 |
| A | MN402 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MN A 402 |
| Chain | Residue |
| A | GLU25 |
| A | HIS215 |
| A | GLU234 |
| A | HIS236 |
| A | MN9401 |
| A | PO4403 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | binding site for residue PO4 A 403 |
| Chain | Residue |
| A | LYS129 |
| A | GLY131 |
| A | SER132 |
| A | SER154 |
| A | CYS182 |
| A | ASN184 |
| A | TYR186 |
| A | SER213 |
| A | HIS215 |
| A | GLU234 |
| A | MN9401 |
| A | MN402 |
| A | HOH501 |
