6PBR
Catalytic domain of E.coli dihydrolipoamide succinyltransferase in I4 space group
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004149 | molecular_function | dihydrolipoyllysine-residue succinyltransferase activity |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0045252 | cellular_component | oxoglutarate dehydrogenase complex |
| B | 0004149 | molecular_function | dihydrolipoyllysine-residue succinyltransferase activity |
| B | 0006099 | biological_process | tricarboxylic acid cycle |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0045252 | cellular_component | oxoglutarate dehydrogenase complex |
| C | 0004149 | molecular_function | dihydrolipoyllysine-residue succinyltransferase activity |
| C | 0006099 | biological_process | tricarboxylic acid cycle |
| C | 0016746 | molecular_function | acyltransferase activity |
| C | 0045252 | cellular_component | oxoglutarate dehydrogenase complex |
| D | 0004149 | molecular_function | dihydrolipoyllysine-residue succinyltransferase activity |
| D | 0006099 | biological_process | tricarboxylic acid cycle |
| D | 0016746 | molecular_function | acyltransferase activity |
| D | 0045252 | cellular_component | oxoglutarate dehydrogenase complex |
| E | 0004149 | molecular_function | dihydrolipoyllysine-residue succinyltransferase activity |
| E | 0006099 | biological_process | tricarboxylic acid cycle |
| E | 0016746 | molecular_function | acyltransferase activity |
| E | 0045252 | cellular_component | oxoglutarate dehydrogenase complex |
| F | 0004149 | molecular_function | dihydrolipoyllysine-residue succinyltransferase activity |
| F | 0006099 | biological_process | tricarboxylic acid cycle |
| F | 0016746 | molecular_function | acyltransferase activity |
| F | 0045252 | cellular_component | oxoglutarate dehydrogenase complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 501 |
| Chain | Residue |
| A | LYS391 |
| A | GLU395 |
| B | LYS351 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | binding site for residue NA B 501 |
| Chain | Residue |
| B | GLU395 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue NA D 501 |
| Chain | Residue |
| D | GLU395 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue NA E 501 |
| Chain | Residue |
| E | GLU395 |
| F | LYS351 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue NA F 501 |
| Chain | Residue |
| F | LYS391 |
| F | GLU395 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | ACT_SITE: ACT_SITE => ECO:0000305|PubMed:10739245, ECO:0000305|PubMed:9677295 |
| Chain | Residue | Details |
| A | HIS375 | |
| A | ASP379 | |
| B | HIS375 | |
| B | ASP379 | |
| C | HIS375 | |
| C | ASP379 | |
| D | HIS375 | |
| D | ASP379 | |
| E | HIS375 | |
| E | ASP379 | |
| F | HIS375 | |
| F | ASP379 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 704 |
| Chain | Residue | Details |
| A | THR323 | electrostatic stabiliser, polar interaction |
| A | HIS375 | activator, proton acceptor, proton donor |
| site_id | MCSA2 |
| Number of Residues | 2 |
| Details | M-CSA 704 |
| Chain | Residue | Details |
| B | THR323 | electrostatic stabiliser, polar interaction |
| B | HIS375 | activator, proton acceptor, proton donor |
| site_id | MCSA3 |
| Number of Residues | 2 |
| Details | M-CSA 704 |
| Chain | Residue | Details |
| C | THR323 | electrostatic stabiliser, polar interaction |
| C | HIS375 | activator, proton acceptor, proton donor |
| site_id | MCSA4 |
| Number of Residues | 2 |
| Details | M-CSA 704 |
| Chain | Residue | Details |
| D | THR323 | electrostatic stabiliser, polar interaction |
| D | HIS375 | activator, proton acceptor, proton donor |
| site_id | MCSA5 |
| Number of Residues | 2 |
| Details | M-CSA 704 |
| Chain | Residue | Details |
| E | THR323 | electrostatic stabiliser, polar interaction |
| E | HIS375 | activator, proton acceptor, proton donor |
| site_id | MCSA6 |
| Number of Residues | 2 |
| Details | M-CSA 704 |
| Chain | Residue | Details |
| F | THR323 | electrostatic stabiliser, polar interaction |
| F | HIS375 | activator, proton acceptor, proton donor |
