6PAM

Structure of a bacterial Atm1-family ABC transporter with MgADP bound

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0016887	molecular_function	ATP hydrolysis activity
A	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
A	0046689	biological_process	response to mercury ion
A	0055085	biological_process	transmembrane transport
A	0140359	molecular_function	ABC-type transporter activity
B	0000166	molecular_function	nucleotide binding
B	0005524	molecular_function	ATP binding
B	0005886	cellular_component	plasma membrane
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0016887	molecular_function	ATP hydrolysis activity
B	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
B	0046689	biological_process	response to mercury ion
B	0055085	biological_process	transmembrane transport
B	0140359	molecular_function	ABC-type transporter activity
C	0000166	molecular_function	nucleotide binding
C	0005524	molecular_function	ATP binding
C	0005886	cellular_component	plasma membrane
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0016887	molecular_function	ATP hydrolysis activity
C	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
C	0046689	biological_process	response to mercury ion
C	0055085	biological_process	transmembrane transport
C	0140359	molecular_function	ABC-type transporter activity
D	0000166	molecular_function	nucleotide binding
D	0005524	molecular_function	ATP binding
D	0005886	cellular_component	plasma membrane
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0016887	molecular_function	ATP hydrolysis activity
D	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
D	0046689	biological_process	response to mercury ion
D	0055085	biological_process	transmembrane transport
D	0140359	molecular_function	ABC-type transporter activity
E	0000166	molecular_function	nucleotide binding
E	0005524	molecular_function	ATP binding
E	0005886	cellular_component	plasma membrane
E	0006811	biological_process	monoatomic ion transport
E	0016020	cellular_component	membrane
E	0016887	molecular_function	ATP hydrolysis activity
E	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
E	0046689	biological_process	response to mercury ion
E	0055085	biological_process	transmembrane transport
E	0140359	molecular_function	ABC-type transporter activity
F	0000166	molecular_function	nucleotide binding
F	0005524	molecular_function	ATP binding
F	0005886	cellular_component	plasma membrane
F	0006811	biological_process	monoatomic ion transport
F	0016020	cellular_component	membrane
F	0016887	molecular_function	ATP hydrolysis activity
F	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
F	0046689	biological_process	response to mercury ion
F	0055085	biological_process	transmembrane transport
F	0140359	molecular_function	ABC-type transporter activity
G	0000166	molecular_function	nucleotide binding
G	0005524	molecular_function	ATP binding
G	0005886	cellular_component	plasma membrane
G	0006811	biological_process	monoatomic ion transport
G	0016020	cellular_component	membrane
G	0016887	molecular_function	ATP hydrolysis activity
G	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
G	0046689	biological_process	response to mercury ion
G	0055085	biological_process	transmembrane transport
G	0140359	molecular_function	ABC-type transporter activity
H	0000166	molecular_function	nucleotide binding
H	0005524	molecular_function	ATP binding
H	0005886	cellular_component	plasma membrane
H	0006811	biological_process	monoatomic ion transport
H	0016020	cellular_component	membrane
H	0016887	molecular_function	ATP hydrolysis activity
H	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
H	0046689	biological_process	response to mercury ion
H	0055085	biological_process	transmembrane transport
H	0140359	molecular_function	ABC-type transporter activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue ADP A 701

Chain	Residue
A	HIS132
A	MG702
A	TYR370
A	ARG374
A	ILE376
A	SER396
A	GLY399
A	LYS400
A	SER401
A	THR402

---

site_id	AC2
Number of Residues	3
Details	binding site for residue MG A 702

Chain	Residue
A	SER401
A	ASP522
A	ADP701

---

site_id	AC3
Number of Residues	11
Details	binding site for residue ADP B 701

Chain	Residue
B	TYR370
B	ARG374
B	ILE376
B	PRO395
B	GLY397
B	ALA398
B	GLY399
B	LYS400
B	SER401
B	THR402
B	MG702

---

site_id	AC4
Number of Residues	3
Details	binding site for residue MG B 702

Chain	Residue
B	SER401
B	ASP522
B	ADP701

---

site_id	AC5
Number of Residues	11
Details	binding site for residue ADP C 701

Chain	Residue
C	LEU133
C	TYR370
C	ARG374
C	ILE376
C	SER396
C	GLY399
C	LYS400
C	SER401
C	THR402
C	ARG405
C	MG702

---

site_id	AC6
Number of Residues	2
Details	binding site for residue MG C 702

Chain	Residue
C	SER401
C	ADP701

---

site_id	AC7
Number of Residues	8
Details	binding site for residue ADP D 701

Chain	Residue
D	TYR370
D	ILE376
D	ALA398
D	GLY399
D	LYS400
D	SER401
D	THR402
D	MG702

---

site_id	AC8
Number of Residues	3
Details	binding site for residue MG D 702

Chain	Residue
D	SER401
D	ASP522
D	ADP701

---

site_id	AC9
Number of Residues	12
Details	binding site for residue ADP E 701

Chain	Residue
E	HIS132
E	ARG135
E	TYR370
E	ARG374
E	GLY397
E	ALA398
E	GLY399
E	LYS400
E	SER401
E	THR402
E	ARG405
E	MG702

---

site_id	AD1
Number of Residues	3
Details	binding site for residue MG E 702

Chain	Residue
E	SER401
E	ASP522
E	ADP701

---

site_id	AD2
Number of Residues	11
Details	binding site for residue ADP F 701

Chain	Residue
F	HIS132
F	TYR370
F	ARG374
F	PRO395
F	GLY397
F	ALA398
F	GLY399
F	LYS400
F	SER401
F	THR402
F	MG702

---

site_id	AD3
Number of Residues	3
Details	binding site for residue MG F 702

Chain	Residue
F	SER401
F	ASP522
F	ADP701

---

site_id	AD4
Number of Residues	10
Details	binding site for residue ADP G 701

Chain	Residue
G	TYR370
G	ARG374
G	PRO395
G	SER396
G	GLY399
G	LYS400
G	SER401
G	ARG405
G	HIS554
G	MG702

---

site_id	AD5
Number of Residues	3
Details	binding site for residue MG G 702

Chain	Residue
G	GLN442
G	GLU523
G	ADP701

---

site_id	AD6
Number of Residues	11
Details	binding site for residue ADP H 701

Chain	Residue
H	SER401
H	THR402
H	ARG405
H	HIS554
H	MG702
H	TYR370
H	ARG374
H	PRO395
H	SER396
H	GLY399
H	LYS400

---

site_id	AD7
Number of Residues	4
Details	binding site for residue MG H 702

Chain	Residue
H	SER401
H	GLN442
H	ASP522
H	ADP701

---

Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LSGGEKQRVAIARTL

Chain	Residue	Details
A	LEU498-LEU512

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1016
Details	Transmembrane: {"description":"Helical"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	288
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"24604198","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	888
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"24604198","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2304
Details	Domain: {"description":"ABC transmembrane type-1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00441","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1872
Details	Domain: {"description":"ABC transporter","evidences":[{"source":"PROSITE-ProRule","id":"PRU00434","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P40416","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	48
Details	Binding site: {"evidences":[{"source":"PubMed","id":"24604198","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4MRP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9NP58","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	88
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00434","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---