6P96

OXA-48 carbapanemase, apo form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008658	molecular_function	penicillin binding
A	0008800	molecular_function	beta-lactamase activity
A	0017001	biological_process	antibiotic catabolic process
B	0008658	molecular_function	penicillin binding
B	0008800	molecular_function	beta-lactamase activity
B	0017001	biological_process	antibiotic catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue CL A 301

Chain	Residue
A	LYS73
A	TRP157
A	HOH517

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site_id	AC2
Number of Residues	2
Details	binding site for residue CL A 302

Chain	Residue
A	ARG206
B	ARG206

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site_id	AC3
Number of Residues	7
Details	binding site for residue CA A 303

Chain	Residue
B	ASP143
B	GLU147
B	HOH416
A	ASP143
A	GLU147
A	CD305
A	HOH425

---

site_id	AC4
Number of Residues	7
Details	binding site for residue CA A 304

Chain	Residue
A	HIS34
A	GLU37
A	GLU256
A	CD306
A	HOH476
A	HOH556
A	HOH564

---

site_id	AC5
Number of Residues	7
Details	binding site for residue CD A 305

Chain	Residue
A	GLU147
A	CA303
A	HOH419
A	HOH500
B	ASP143
B	HOH406
B	HOH447

---

site_id	AC6
Number of Residues	6
Details	binding site for residue CD A 306

Chain	Residue
A	GLU37
A	HIS38
A	GLU125
A	GLU256
A	CA304
A	HOH556

---

site_id	AC7
Number of Residues	3
Details	binding site for residue CL B 301

Chain	Residue
B	LYS73
B	TRP157
B	HOH543

---

site_id	AC8
Number of Residues	4
Details	binding site for residue CL B 302

Chain	Residue
B	HOH568
B	HOH570
B	HOH572
B	HOH575

---

site_id	AC9
Number of Residues	5
Details	binding site for residue CA B 303

Chain	Residue
A	GLU216
B	HIS34
B	GLU37
B	GLU256
B	HOH401

---

Functional Information from PROSITE/UniProt

site_id	PS00337
Number of Residues	11
Details	BETA_LACTAMASE_D Beta-lactamase class-D active site. PaSTFKIPnSL

Chain	Residue	Details
A	PRO68-LEU78

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Acyl-ester intermediate","evidences":[{"source":"PIRSR","id":"PIRSR602137-50","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"25406838","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26731698","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31358584","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32150407","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4WMC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FAQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FAS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6P97","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6P98","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6P99","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6P9C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6V1O","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q8RLA6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P13661","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"N6-carboxylysine","evidences":[{"source":"PIRSR","id":"PIRSR602137-50","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19477418","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25406838","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3HBR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4WMC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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