6P66

The crystal structure of the XPB complex with Bax1 from Archaeoglobus fulgidus at 3.0 Angstrom resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0005524	molecular_function	ATP binding
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0043138	molecular_function	3'-5' DNA helicase activity
A	0120545	molecular_function	nucleic acid conformation isomerase activity
A	0140097	molecular_function	catalytic activity, acting on DNA
C	0003677	molecular_function	DNA binding
C	0005524	molecular_function	ATP binding
C	0016787	molecular_function	hydrolase activity
C	0016887	molecular_function	ATP hydrolysis activity
C	0043138	molecular_function	3'-5' DNA helicase activity
C	0120545	molecular_function	nucleic acid conformation isomerase activity
C	0140097	molecular_function	catalytic activity, acting on DNA

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue CL A 501

Chain	Residue
A	ARG444
A	HOH629

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	288
Details	Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	14
Details	Region: {"description":"Flexible hinge region","evidences":[{"source":"PubMed","id":"16600867","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	122
Details	Region: {"description":"ThM region","evidences":[{"source":"PubMed","id":"16600867","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Motif: {"description":"DEAH box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Motif: {"description":"RED motif","evidences":[{"source":"PubMed","id":"16600867","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Site: {"description":"Wedge residue","evidences":[{"source":"UniProtKB","id":"Q970I2","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	59
Details	Region: {"description":"DRD domain","evidences":[{"source":"PubMed","id":"16600867","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	290
Details	Region: {"description":"N-terminal domain (NTD)","evidences":[{"source":"PubMed","id":"32374860","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	184
Details	Region: {"description":"Central domain (CRD)","evidences":[{"source":"PubMed","id":"32374860","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	204
Details	Region: {"description":"Nuclease domain (NUS)","evidences":[{"source":"PubMed","id":"32374860","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"32374860","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---