Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004386 | molecular_function | helicase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006281 | biological_process | DNA repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0120545 | molecular_function | nucleic acid conformation isomerase activity |
| A | 0140097 | molecular_function | catalytic activity, acting on DNA |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004518 | molecular_function | nuclease activity |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0006281 | biological_process | DNA repair |
| B | 0006974 | biological_process | DNA damage response |
| B | 0016787 | molecular_function | hydrolase activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0003677 | molecular_function | DNA binding |
| C | 0004386 | molecular_function | helicase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006281 | biological_process | DNA repair |
| C | 0006974 | biological_process | DNA damage response |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0120545 | molecular_function | nucleic acid conformation isomerase activity |
| C | 0140097 | molecular_function | catalytic activity, acting on DNA |
| D | 0003677 | molecular_function | DNA binding |
| D | 0004518 | molecular_function | nuclease activity |
| D | 0004519 | molecular_function | endonuclease activity |
| D | 0006281 | biological_process | DNA repair |
| D | 0006974 | biological_process | DNA damage response |
| D | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 501 |
| Chain | Residue |
| A | ARG444 |
| A | HOH629 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 288 |
| Details | Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | Region: {"description":"Flexible hinge region","evidences":[{"source":"PubMed","id":"16600867","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 122 |
| Details | Region: {"description":"ThM region","evidences":[{"source":"PubMed","id":"16600867","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Motif: {"description":"DEAH box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Motif: {"description":"RED motif","evidences":[{"source":"PubMed","id":"16600867","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Site: {"description":"Wedge residue","evidences":[{"source":"UniProtKB","id":"Q970I2","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 59 |
| Details | Region: {"description":"DRD domain","evidences":[{"source":"PubMed","id":"16600867","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI9 |
| Number of Residues | 290 |
| Details | Region: {"description":"N-terminal domain (NTD)","evidences":[{"source":"PubMed","id":"32374860","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI10 |
| Number of Residues | 184 |
| Details | Region: {"description":"Central domain (CRD)","evidences":[{"source":"PubMed","id":"32374860","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI11 |
| Number of Residues | 204 |
| Details | Region: {"description":"Nuclease domain (NUS)","evidences":[{"source":"PubMed","id":"32374860","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI12 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"32374860","evidenceCode":"ECO:0000305"}]} |
