Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004674 | molecular_function | protein serine/threonine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
| C | 0004672 | molecular_function | protein kinase activity |
| C | 0004674 | molecular_function | protein serine/threonine kinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006468 | biological_process | protein phosphorylation |
| D | 0004672 | molecular_function | protein kinase activity |
| D | 0004674 | molecular_function | protein serine/threonine kinase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue O1V A 2500 |
| Chain | Residue |
| A | ARG100 |
| A | TYR171 |
| A | MET172 |
| A | LEU221 |
| A | ALA231 |
| A | ASP232 |
| A | GLY101 |
| A | VAL106 |
| A | ALA119 |
| A | LYS121 |
| A | GLU140 |
| A | VAL153 |
| A | MET169 |
| A | GLU170 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue O1V B 2500 |
| Chain | Residue |
| B | ILE98 |
| B | ARG100 |
| B | GLY101 |
| B | VAL106 |
| B | ALA119 |
| B | LYS121 |
| B | GLU140 |
| B | VAL153 |
| B | MET169 |
| B | GLU170 |
| B | TYR171 |
| B | MET172 |
| B | LEU221 |
| B | ALA231 |
| B | ASP232 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | binding site for residue O1V C 2500 |
| Chain | Residue |
| C | ILE98 |
| C | ARG100 |
| C | GLY101 |
| C | VAL106 |
| C | ALA119 |
| C | LYS121 |
| C | GLU140 |
| C | VAL153 |
| C | MET169 |
| C | GLU170 |
| C | TYR171 |
| C | MET172 |
| C | LEU221 |
| C | ALA231 |
| C | ASP232 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | binding site for residue O1V D 2500 |
| Chain | Residue |
| D | ARG100 |
| D | GLY101 |
| D | VAL106 |
| D | ALA119 |
| D | LYS121 |
| D | GLU140 |
| D | VAL153 |
| D | MET169 |
| D | GLU170 |
| D | TYR171 |
| D | MET172 |
| D | LEU221 |
| D | ALA231 |
| D | ASP232 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGRGAFGEVQlVrhkasqkv..........YAMK |
| Chain | Residue | Details |
| A | ILE98-LYS121 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. LiHrDVKpdNMLL |
| Chain | Residue | Details |
| A | LEU210-LEU222 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 262 |
| Details | Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 36 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphothreonine; by ROCK2","evidences":[{"source":"UniProtKB","id":"Q62868","evidenceCode":"ECO:0000250"}]} |
