6OZP

Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 180 min soak in 10 mM Mn2+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004519	molecular_function	endonuclease activity
A	0006281	biological_process	DNA repair
B	0004519	molecular_function	endonuclease activity
B	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MN A 301

Chain	Residue
A	ASP52
A	ASP240
A	HOH420
A	HOH452
C	U12

---

site_id	AC2
Number of Residues	6
Details	binding site for residue MN A 302

Chain	Residue
C	U12
c	A11
A	ASP52
A	ASP126
A	HOH413
A	HOH444

---

site_id	AC3
Number of Residues	6
Details	binding site for residue MN A 303

Chain	Residue
A	LEU45
A	GLN46
A	HOH408
A	HOH448
A	HOH467
A	HOH498

---

site_id	AC4
Number of Residues	4
Details	binding site for residue GOL A 304

Chain	Residue
A	VAL77
A	GLU80
A	HOH437
A	HOH464

---

site_id	AC5
Number of Residues	5
Details	binding site for residue GOL A 305

Chain	Residue
A	ASP39
A	SER41
A	SER43
B	GLN112
B	GLU113

---

site_id	AC6
Number of Residues	2
Details	binding site for residue PG4 A 306

Chain	Residue
A	LYS25
A	HOH424

---

site_id	AC7
Number of Residues	2
Details	binding site for residue EDO A 307

Chain	Residue
A	TYR79
A	GLU80

---

site_id	AC8
Number of Residues	2
Details	binding site for residue EDO A 308

Chain	Residue
A	ASP201
A	HIS202

---

site_id	AC9
Number of Residues	2
Details	binding site for residue EDO A 309

Chain	Residue
A	HIS132
A	GLN133

---

site_id	AD1
Number of Residues	6
Details	binding site for residue PGE A 310

Chain	Residue
A	ASP32
A	ALA35
A	ARG38
A	HOH471
B	LEU145
B	THR146

---

site_id	AD2
Number of Residues	2
Details	binding site for residue PGE A 311

Chain	Residue
A	HIS225
A	HIS226

---

site_id	AD3
Number of Residues	5
Details	binding site for residue MN B 301

Chain	Residue
B	ASP52
B	ASP240
B	HOH417
B	HOH444
D	U12

---

site_id	AD4
Number of Residues	5
Details	binding site for residue MN B 302

Chain	Residue
B	GLU12
B	GLU245
B	HOH416
B	HOH434
B	HOH486

---

site_id	AD5
Number of Residues	7
Details	binding site for residue MN B 303

Chain	Residue
B	GLN46
B	TYR72
B	HOH422
B	HOH446
B	HOH455
B	HOH462
B	HOH475

---

site_id	AD6
Number of Residues	10
Details	binding site for residue PG4 B 304

Chain	Residue
A	ARG27
A	VAL144
A	LEU145
A	THR146
A	GLU147
A	GLU171
B	ASP32
B	ALA35
B	ARG38
B	HOH485

---

site_id	AD7
Number of Residues	2
Details	binding site for residue EDO B 305

Chain	Residue
B	LYS25
B	HOH437

---

site_id	AD8
Number of Residues	2
Details	binding site for residue EDO B 306

Chain	Residue
B	ASP201
B	HIS202

---

site_id	AD9
Number of Residues	1
Details	binding site for residue EDO B 307

Chain	Residue
B	VAL77

---

site_id	AE1
Number of Residues	4
Details	binding site for residue PGE B 308

Chain	Residue
B	HIS225
B	HIS226
B	CYS228
B	HOH472

---

site_id	AE2
Number of Residues	6
Details	binding site for residue MN B 309

Chain	Residue
B	ASP52
B	ASP126
B	HOH421
B	HOH429
D	U12
d	A11

---

site_id	AE3
Number of Residues	6
Details	binding site for residue MN C 101

Chain	Residue
A	HOH432
C	U12
C	A13
C	HOH212
C	HOH218
C	HOH219

---

site_id	AE4
Number of Residues	1
Details	binding site for residue MN C 102

Chain	Residue
C	HOH204

---

site_id	AE5
Number of Residues	6
Details	binding site for residue MN D 101

Chain	Residue
B	HOH438
D	U12
D	A13
D	HOH216
D	HOH218
D	HOH225

---

site_id	AE6
Number of Residues	6
Details	binding site for residue MN D 102

Chain	Residue
D	HOH207
D	HOH213
D	HOH228
D	HOH229
C	HOH223
D	HOH204

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ASP52
A	ASP126
B	ASP52
B	ASP126

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	SITE: Interaction with target DNA => ECO:0000250

Chain	Residue	Details
A	TYR91
B	TYR91

---