6OOV
Crystal structure of HMCES SRAP domain in complex with palindromic 3' overhang DNA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003697 | molecular_function | single-stranded DNA binding |
| A | 0006974 | biological_process | DNA damage response |
| A | 0106300 | biological_process | protein-DNA covalent cross-linking repair |
| B | 0003697 | molecular_function | single-stranded DNA binding |
| B | 0006974 | biological_process | DNA damage response |
| B | 0106300 | biological_process | protein-DNA covalent cross-linking repair |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"31235913","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30554877","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"37519246","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37950866","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Required for sensing abasic sites","evidences":[{"source":"UniProtKB","id":"P76318","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Required to stabilize abasic sites","evidences":[{"source":"UniProtKB","id":"P76318","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Thiazolidine linkage to a ring-opened DNA abasic site","evidences":[{"source":"PubMed","id":"31235913","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
