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6OO3

Cryo-EM structure of the C4-symmetric TRPV2/RTx complex in amphipol resolved to 2.9 A

Functional Information from GO Data
ChainGOidnamespacecontents
A0005216molecular_functionmonoatomic ion channel activity
A0005261molecular_functionmonoatomic cation channel activity
A0005262molecular_functioncalcium channel activity
A0005886cellular_componentplasma membrane
A0006811biological_processmonoatomic ion transport
A0009266biological_processresponse to temperature stimulus
A0009986cellular_componentcell surface
A0016020cellular_componentmembrane
A0030424cellular_componentaxon
A0032584cellular_componentgrowth cone membrane
A0042802molecular_functionidentical protein binding
A0044295cellular_componentaxonal growth cone
A0044297cellular_componentcell body
A0045773biological_processpositive regulation of axon extension
A0055085biological_processtransmembrane transport
A0070588biological_processcalcium ion transmembrane transport
A0090280biological_processpositive regulation of calcium ion import
A0098703biological_processcalcium ion import across plasma membrane
A0120162biological_processpositive regulation of cold-induced thermogenesis
B0005216molecular_functionmonoatomic ion channel activity
B0005261molecular_functionmonoatomic cation channel activity
B0005262molecular_functioncalcium channel activity
B0005886cellular_componentplasma membrane
B0006811biological_processmonoatomic ion transport
B0009266biological_processresponse to temperature stimulus
B0009986cellular_componentcell surface
B0016020cellular_componentmembrane
B0030424cellular_componentaxon
B0032584cellular_componentgrowth cone membrane
B0042802molecular_functionidentical protein binding
B0044295cellular_componentaxonal growth cone
B0044297cellular_componentcell body
B0045773biological_processpositive regulation of axon extension
B0055085biological_processtransmembrane transport
B0070588biological_processcalcium ion transmembrane transport
B0090280biological_processpositive regulation of calcium ion import
B0098703biological_processcalcium ion import across plasma membrane
B0120162biological_processpositive regulation of cold-induced thermogenesis
C0005216molecular_functionmonoatomic ion channel activity
C0005261molecular_functionmonoatomic cation channel activity
C0005262molecular_functioncalcium channel activity
C0005886cellular_componentplasma membrane
C0006811biological_processmonoatomic ion transport
C0009266biological_processresponse to temperature stimulus
C0009986cellular_componentcell surface
C0016020cellular_componentmembrane
C0030424cellular_componentaxon
C0032584cellular_componentgrowth cone membrane
C0042802molecular_functionidentical protein binding
C0044295cellular_componentaxonal growth cone
C0044297cellular_componentcell body
C0045773biological_processpositive regulation of axon extension
C0055085biological_processtransmembrane transport
C0070588biological_processcalcium ion transmembrane transport
C0090280biological_processpositive regulation of calcium ion import
C0098703biological_processcalcium ion import across plasma membrane
C0120162biological_processpositive regulation of cold-induced thermogenesis
D0005216molecular_functionmonoatomic ion channel activity
D0005261molecular_functionmonoatomic cation channel activity
D0005262molecular_functioncalcium channel activity
D0005886cellular_componentplasma membrane
D0006811biological_processmonoatomic ion transport
D0009266biological_processresponse to temperature stimulus
D0009986cellular_componentcell surface
D0016020cellular_componentmembrane
D0030424cellular_componentaxon
D0032584cellular_componentgrowth cone membrane
D0042802molecular_functionidentical protein binding
D0044295cellular_componentaxonal growth cone
D0044297cellular_componentcell body
D0045773biological_processpositive regulation of axon extension
D0055085biological_processtransmembrane transport
D0070588biological_processcalcium ion transmembrane transport
D0090280biological_processpositive regulation of calcium ion import
D0098703biological_processcalcium ion import across plasma membrane
D0120162biological_processpositive regulation of cold-induced thermogenesis
Functional Information from PDB Data
site_idAC1
Number of Residues8
Detailsbinding site for residue 6EU A 1001
ChainResidue
ATYR469
ASER470
AMET505
ATHR508
AASN509
AGLU528
AILE531
DLEU629

site_idAC2
Number of Residues8
Detailsbinding site for residue 6EU B 1001
ChainResidue
BTYR469
BSER470
BMET505
BTHR508
BASN509
BGLU528
BILE531
ALEU629

site_idAC3
Number of Residues8
Detailsbinding site for residue 6EU C 1001
ChainResidue
BLEU629
CTYR469
CSER470
CMET505
CTHR508
CASN509
CGLU528
CILE531

site_idAC4
Number of Residues8
Detailsbinding site for residue 6EU D 1001
ChainResidue
CLEU629
DTYR469
DSER470
DMET505
DTHR508
DASN509
DGLU528
DILE531

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PDB entries from 2024-11-06

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