6OO2
Vps4 with Cyclic Peptide Bound in the Central Pore
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005524 | molecular_function | ATP binding |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0016887 | molecular_function | ATP hydrolysis activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0016887 | molecular_function | ATP hydrolysis activity |
| E | 0005524 | molecular_function | ATP binding |
| E | 0016887 | molecular_function | ATP hydrolysis activity |
| F | 0005524 | molecular_function | ATP binding |
| F | 0016887 | molecular_function | ATP hydrolysis activity |
| H | 0032511 | biological_process | late endosome to vacuole transport via multivesicular body sorting pathway |
| I | 0032511 | biological_process | late endosome to vacuole transport via multivesicular body sorting pathway |
| J | 0032511 | biological_process | late endosome to vacuole transport via multivesicular body sorting pathway |
| K | 0032511 | biological_process | late endosome to vacuole transport via multivesicular body sorting pathway |
| L | 0032511 | biological_process | late endosome to vacuole transport via multivesicular body sorting pathway |
| M | 0032511 | biological_process | late endosome to vacuole transport via multivesicular body sorting pathway |
| N | 0032511 | biological_process | late endosome to vacuole transport via multivesicular body sorting pathway |
| O | 0032511 | biological_process | late endosome to vacuole transport via multivesicular body sorting pathway |
| P | 0032511 | biological_process | late endosome to vacuole transport via multivesicular body sorting pathway |
| Q | 0032511 | biological_process | late endosome to vacuole transport via multivesicular body sorting pathway |
| R | 0032511 | biological_process | late endosome to vacuole transport via multivesicular body sorting pathway |
| S | 0032511 | biological_process | late endosome to vacuole transport via multivesicular body sorting pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue ADP A 501 |
| Chain | Residue |
| A | ASP134 |
| A | MET307 |
| A | GLY336 |
| A | SER337 |
| A | ALA340 |
| A | BEF502 |
| A | MG503 |
| B | ARG288 |
| A | VAL135 |
| A | ALA136 |
| A | GLY176 |
| A | THR177 |
| A | GLY178 |
| A | LYS179 |
| A | SER180 |
| A | TYR181 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue BEF A 502 |
| Chain | Residue |
| A | PRO175 |
| A | GLY176 |
| A | LYS179 |
| A | ASN277 |
| A | ADP501 |
| A | MG503 |
| B | ARG288 |
| B | ARG289 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 503 |
| Chain | Residue |
| A | SER180 |
| A | ADP501 |
| A | BEF502 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | binding site for residue ADP B 501 |
| Chain | Residue |
| B | ASP134 |
| B | ALA136 |
| B | GLY176 |
| B | THR177 |
| B | LYS179 |
| B | SER180 |
| B | TYR181 |
| B | GLY336 |
| B | BEF502 |
| B | MG503 |
| C | ARG288 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue BEF B 502 |
| Chain | Residue |
| B | PRO174 |
| B | PRO175 |
| B | GLY176 |
| B | LYS179 |
| B | ASN277 |
| B | ADP501 |
| B | MG503 |
| C | ARG288 |
| C | ARG289 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 503 |
| Chain | Residue |
| B | SER180 |
| B | ADP501 |
| B | BEF502 |
| site_id | AC7 |
| Number of Residues | 13 |
| Details | binding site for residue ADP C 501 |
| Chain | Residue |
| C | ASP134 |
| C | VAL135 |
| C | ALA136 |
| C | GLY176 |
| C | THR177 |
| C | GLY178 |
| C | LYS179 |
| C | SER180 |
| C | TYR181 |
| C | GLY336 |
| C | BEF502 |
| C | MG503 |
| D | ARG288 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue BEF C 502 |
| Chain | Residue |
| C | PRO174 |
| C | PRO175 |
| C | GLY176 |
| C | LYS179 |
| C | ADP501 |
| C | MG503 |
| D | ARG288 |
| D | ARG289 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue MG C 503 |
| Chain | Residue |
| C | SER180 |
| C | ADP501 |
| C | BEF502 |
| site_id | AD1 |
| Number of Residues | 15 |
| Details | binding site for residue ADP D 501 |
| Chain | Residue |
| D | ASP134 |
| D | VAL135 |
| D | ALA136 |
| D | PRO175 |
| D | GLY176 |
| D | THR177 |
| D | GLY178 |
| D | LYS179 |
| D | SER180 |
| D | TYR181 |
| D | GLY336 |
| D | SER337 |
| D | MG502 |
| E | ARG288 |
| E | ARG289 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue MG D 502 |
| Chain | Residue |
| D | SER180 |
| D | ADP501 |
| site_id | AD3 |
| Number of Residues | 9 |
| Details | binding site for residue ADP E 501 |
| Chain | Residue |
| E | GLY336 |
| E | ASP134 |
| E | ALA136 |
| E | GLY176 |
| E | THR177 |
| E | GLY178 |
| E | LYS179 |
| E | SER180 |
| E | TYR181 |
Functional Information from PROSITE/UniProt
| site_id | PS00674 |
| Number of Residues | 20 |
| Details | AAA AAA-protein family signature. VlVLgATNipwqLDsAIrrR |
| Chain | Residue | Details |
| A | VAL270-ARG289 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000255 |
| Chain | Residue | Details |
| A | GLY173 | |
| B | GLY173 | |
| C | GLY173 | |
| D | GLY173 | |
| E | GLY173 | |
| F | GLY173 |
