Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue MU7 A 501 |
| Chain | Residue |
| A | ILE227 |
| A | PHE356 |
| A | GLY367 |
| A | ASP368 |
| A | LEU369 |
| A | HOH781 |
| A | LYS233 |
| A | VAL235 |
| A | VAL281 |
| A | THR301 |
| A | LEU303 |
| A | MET304 |
| A | THR305 |
| A | GLY307 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 502 |
| Chain | Residue |
| A | PRO392 |
| A | TYR422 |
| A | ARG434 |
| A | VAL435 |
| A | GLY438 |
| A | VAL439 |
| A | ILE460 |
| A | GLN462 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 503 |
| Chain | Residue |
| A | ALA382 |
| A | VAL383 |
| A | ILE384 |
| A | GLY385 |
| A | PRO387 |
| A | ASN427 |
| A | ALA428 |
| A | HOH664 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 504 |
| Chain | Residue |
| A | GLU424 |
| A | ARG434 |
| A | ALA442 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 505 |
| Chain | Residue |
| A | TYR432 |
| A | THR436 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue ACT A 506 |
| Chain | Residue |
| A | ASP203 |
| A | ACT507 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue ACT A 507 |
| Chain | Residue |
| A | THR244 |
| A | ACT506 |
| A | HOH616 |
| A | HOH721 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 508 |
| Chain | Residue |
| A | MET319 |
| A | ALA416 |
| A | HOH654 |
Functional Information from PROSITE/UniProt
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IiHrDLKcdNIFI |
| Chain | Residue | Details |
| A | ILE345-ILE357 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 258 |
| Details | Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"10828064","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"16083423","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9H4A3","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24803536","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"4Q2A","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by autocatalysis","evidences":[{"source":"PubMed","id":"12374799","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by autocatalysis","evidences":[{"source":"PubMed","id":"12374799","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22544747","evidenceCode":"ECO:0000269"}]} |
