Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6OEA

Crystal structure of HMCES SRAP domain in complex with longer 3' overhang DNA

Replaces:  6NLC
Functional Information from GO Data
ChainGOidnamespacecontents
A0003697molecular_functionsingle-stranded DNA binding
A0006974biological_processDNA damage response
A0106300biological_processprotein-DNA covalent cross-linking repair
Functional Information from PDB Data
site_idAC1
Number of Residues6
Detailsbinding site for residue EDO A 301
ChainResidue
ALYS37
AASN49
APRO72
AVAL191
ALEU192
ATYR193

site_idAC2
Number of Residues6
Detailsbinding site for residue EDO A 302
ChainResidue
AASP36
AHOH403
AHOH431
AARG16
AASP34
APRO35

site_idAC3
Number of Residues6
Detailsbinding site for residue EDO A 303
ChainResidue
AALA17
ACYS18
ALEU53
AGLU220
AHOH419
AHOH433

site_idAC4
Number of Residues3
Detailsbinding site for residue EDO A 304
ChainResidue
AASP34
AALA71
APRO72

site_idAC5
Number of Residues3
Detailsbinding site for residue EDO C 101
ChainResidue
AGLN47
AASN93
CDG5

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: Nucleophile => ECO:0000269|PubMed:31235913, ECO:0000305|PubMed:30554877
ChainResidueDetails
ACYS2

site_idSWS_FT_FI2
Number of Residues1
DetailsACT_SITE: ACT_SITE => ECO:0000269|PubMed:37519246, ECO:0000269|PubMed:37950866
ChainResidueDetails
AGLU127

site_idSWS_FT_FI3
Number of Residues1
DetailsSITE: Required for sensing abasic sites => ECO:0000250|UniProtKB:P76318
ChainResidueDetails
AGLU127

site_idSWS_FT_FI4
Number of Residues1
DetailsSITE: Required to stabilize abasic sites => ECO:0000250|UniProtKB:P76318
ChainResidueDetails
AHIS210

site_idSWS_FT_FI5
Number of Residues1
DetailsMOD_RES: Thiazolidine linkage to a ring-opened DNA abasic site => ECO:0000269|PubMed:31235913
ChainResidueDetails
ACYS2

site_idSWS_FT_FI6
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
ASER160

site_idSWS_FT_FI7
Number of Residues3
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
ChainResidueDetails
ALYS148
ALYS151

226707

PDB entries from 2024-10-30

PDB statisticsPDBj update infoContact PDBjnumon