6OAL

Structure of human PARG complexed with JA2120

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004649	molecular_function	poly(ADP-ribose) glycohydrolase activity
A	0005975	biological_process	carbohydrate metabolic process
A	0006282	biological_process	regulation of DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue M0P A 1001

Chain	Residue
A	THR725
A	PHE900
A	PHE902
A	HOH1195
A	HOH1212
A	ILE726
A	GLU727
A	PHE738
A	VAL753
A	GLN754
A	TYR792
A	TYR795
A	ASN869

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	185
Details	Region: {"description":"Catalytic","evidences":[{"source":"PubMed","id":"23251397","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"evidences":[{"source":"PubMed","id":"23251397","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Active site: {"evidences":[{"source":"PubMed","id":"21892188","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23251397","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23251397","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30472116","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9QYM2","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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