6O9U

KirBac3.1 at a resolution of 2 Angstroms

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005242	molecular_function	inward rectifier potassium channel activity
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0006813	biological_process	potassium ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0034702	cellular_component	monoatomic ion channel complex
A	0034765	biological_process	regulation of monoatomic ion transmembrane transport
A	0042802	molecular_function	identical protein binding
A	1990573	biological_process	potassium ion import across plasma membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue TMO A 401

Chain	Residue
A	TYR132
A	THR136
A	PHE250
A	ALA251
A	GLN252
A	K410
A	K410
A	K410
A	K410

---

site_id	AC2
Number of Residues	4
Details	binding site for residue TMO A 402

Chain	Residue
A	GLU173
A	ASP175
A	THR244
A	ASN253

---

site_id	AC3
Number of Residues	2
Details	binding site for residue TMO A 403

Chain	Residue
A	ASP197
A	LEU198

---

site_id	AC4
Number of Residues	12
Details	binding site for residue K A 405

Chain	Residue
A	GLY98
A	GLY98
A	GLY98
A	GLY98
A	TYR99
A	TYR99
A	TYR99
A	TYR99
A	K406
A	K406
A	K406
A	K406

---

site_id	AC5
Number of Residues	16
Details	binding site for residue K A 406

Chain	Residue
A	ILE97
A	ILE97
A	ILE97
A	ILE97
A	GLY98
A	GLY98
A	GLY98
A	GLY98
A	K405
A	K405
A	K405
A	K405
A	K407
A	K407
A	K407
A	K407

---

site_id	AC6
Number of Residues	16
Details	binding site for residue K A 407

Chain	Residue
A	THR96
A	THR96
A	THR96
A	THR96
A	ILE97
A	ILE97
A	ILE97
A	ILE97
A	K406
A	K406
A	K406
A	K406
A	BA413
A	BA413
A	BA413
A	BA413

---

site_id	AC7
Number of Residues	4
Details	binding site for residue K A 409

Chain	Residue
A	K410
A	K410
A	K410
A	K410

---

site_id	AC8
Number of Residues	8
Details	binding site for residue K A 410

Chain	Residue
A	TMO401
A	TMO401
A	TMO401
A	TMO401
A	K409
A	K409
A	K409
A	K409

---

site_id	AC9
Number of Residues	3
Details	binding site for residue K A 411

Chain	Residue
A	K412
A	K412
A	HOH634

---

site_id	AD1
Number of Residues	5
Details	binding site for residue K A 412

Chain	Residue
A	ALA95
A	THR96
A	K411
A	K411
A	HOH634

---

site_id	AD2
Number of Residues	8
Details	binding site for residue BA A 413

Chain	Residue
A	THR96
A	THR96
A	THR96
A	THR96
A	K407
A	K407
A	K407
A	K407

---

site_id	AD3
Number of Residues	4
Details	binding site for residue CL A 414

Chain	Residue
A	ARG194
A	THR201
A	ARG202
A	PCW416

---

site_id	AD4
Number of Residues	4
Details	binding site for residue PCW A 415

Chain	Residue
A	THR60
A	MET121
A	GLY123
A	ALA127

---

site_id	AD5
Number of Residues	8
Details	binding site for residue PCW A 416

Chain	Residue
A	MET215
A	CL414
A	Z3P417
A	HOH620
A	PHE192
A	ARG193
A	ARG194
A	THR213

---

site_id	AD6
Number of Residues	14
Details	binding site for residue Z3P A 417

Chain	Residue
A	ARG193
A	PHE208
A	SER209
A	LEU210
A	SER211
A	TRP212
A	THR213
A	PHE275
A	ARG283
A	PCW416
A	HOH517
A	HOH524
A	HOH543
A	HOH547

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	45
Details	Transmembrane: {"description":"Helical"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Topological domain: {"description":"Extracellular"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	Intramembrane: {"description":"Helical; Pore-forming"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	163
Details	Topological domain: {"description":"Cytoplasmic"}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Motif: {"description":"Selectivity filter"}

Chain

Residue

Details

---