6O7Y
Trypanosoma cruzi EIF4E5 translation initiation factor in complex with cap-4
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000340 | molecular_function | RNA 7-methylguanosine cap binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003743 | molecular_function | translation initiation factor activity |
| A | 0006412 | biological_process | translation |
| A | 0006413 | biological_process | translational initiation |
| A | 0016281 | cellular_component | eukaryotic translation initiation factor 4F complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue LRM A 301 |
| Chain | Residue |
| A | LEU20 |
| A | ASP95 |
| A | ARG133 |
| A | ARG137 |
| A | PRO138 |
| A | ASN139 |
| A | GLN140 |
| A | LEU145 |
| A | ARG147 |
| A | LEU156 |
| A | ASP160 |
| A | PRO22 |
| A | HOH407 |
| A | HOH441 |
| A | VAL25 |
| A | TRP33 |
| A | ASN68 |
| A | SER82 |
| A | TYR83 |
| A | GLU84 |
| A | ARG91 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | PRO163 |
| A | ARG166 |
| A | HOH408 |
| A | HOH437 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | HIS6 |
| A | ARG166 |
| A | PHE176 |
| A | ILE180 |
| A | MET181 |
| A | HOH431 |
| A | HOH442 |
