Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6O64

Crystal Structure of Arabidopsis thaliana Spermidine Synthase isoform 2 (AtSPDS2)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0006595	biological_process	polyamine metabolic process
B	0003824	molecular_function	catalytic activity
B	0006595	biological_process	polyamine metabolic process
C	0003824	molecular_function	catalytic activity
C	0006595	biological_process	polyamine metabolic process
D	0003824	molecular_function	catalytic activity
D	0006595	biological_process	polyamine metabolic process
E	0003824	molecular_function	catalytic activity
E	0006595	biological_process	polyamine metabolic process
F	0003824	molecular_function	catalytic activity
F	0006595	biological_process	polyamine metabolic process
G	0003824	molecular_function	catalytic activity
G	0006595	biological_process	polyamine metabolic process
H	0003824	molecular_function	catalytic activity
H	0006595	biological_process	polyamine metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	binding site for residue ACT A 401

Chain	Residue
B	SER270

site_id	AC2
Number of Residues	7
Details	binding site for residue PEG A 402

Chain	Residue
A	GLN101
A	ASP205
A	SER206
A	ASP208
A	TYR274
A	PRO275
A	HOH519

site_id	AC3
Number of Residues	9
Details	binding site for residue PEG B 401

Chain	Residue
B	TYR110
B	ASP205
B	SER206
B	ASP208
B	TYR274
B	PRO275
B	HOH508
B	HOH535
B	GLN101

site_id	AC4
Number of Residues	1
Details	binding site for residue FMT B 402

Chain	Residue
B	SER306

site_id	AC5
Number of Residues	8
Details	binding site for residue PEG C 401

Chain	Residue
C	GLN101
C	TYR110
C	ASP205
C	SER206
C	ASP208
C	GLN238
C	TYR274
C	HOH542

site_id	AC6
Number of Residues	5
Details	binding site for residue MLI D 401

Chain	Residue
C	VAL278
C	HOH507
D	SER270
D	HOH520
D	HOH545

site_id	AC7
Number of Residues	7
Details	binding site for residue PEG D 402

Chain	Residue
D	GLN101
D	TYR110
D	ASP205
D	SER206
D	ASP208
D	GLN238
D	TYR274

site_id	AC8
Number of Residues	2
Details	binding site for residue PEG D 403

Chain	Residue
D	TRP51
D	HOH544

site_id	AC9
Number of Residues	2
Details	binding site for residue PEG D 404

Chain	Residue
D	PRO49
D	TRP51

site_id	AD1
Number of Residues	3
Details	binding site for residue MLI E 401

Chain	Residue
E	HOH548
F	ALA323
F	HOH536

site_id	AD2
Number of Residues	10
Details	binding site for residue EDO E 402

Chain	Residue
E	GLN111
E	GLY133
E	GLY134
E	ASP135
E	GLY136
E	GLY137
E	VAL138
E	LEU139
E	HOH504
E	HOH597

site_id	AD3
Number of Residues	5
Details	binding site for residue MLI E 403

Chain	Residue
E	GLU155
E	ILE156
E	GLY185
E	ASP186
E	GLY187

site_id	AD4
Number of Residues	11
Details	binding site for residue PEG E 404

Chain	Residue
E	VAL99
E	GLN101
E	TYR110
E	ASP205
E	SER206
E	ASP208
E	TYR274
E	PRO275
E	HOH502
E	HOH520
E	HOH538

site_id	AD5
Number of Residues	3
Details	binding site for residue FMT E 405

Chain	Residue
E	PHE330
F	HOH585
F	HOH591

site_id	AD6
Number of Residues	6
Details	binding site for residue FMT E 406

Chain	Residue
E	ASN265
E	TYR266
E	LYS294
E	PHE325
E	HOH625
G	GLN290

site_id	AD7
Number of Residues	4
Details	binding site for residue ACT F 401

Chain	Residue
E	ALA323
F	SER322
F	ALA323
F	HOH551

site_id	AD8
Number of Residues	8
Details	binding site for residue PEG F 402

Chain	Residue
F	TYR110
F	ASP205
F	SER206
F	ASP208
F	GLN238
F	TYR274
F	PRO275
F	HOH537

site_id	AD9
Number of Residues	8
Details	binding site for residue PEG F 403

Chain	Residue
H	HOH513
F	LYS126
F	GLU149
F	HOH504
F	HOH622
H	ASN124
H	LYS126
H	SER147

site_id	AE1
Number of Residues	10
Details	binding site for residue PEG G 401

Chain	Residue
G	VAL99
G	GLN101
G	TYR110
G	ASP205
G	SER206
G	ASP208
G	TYR274
G	HOH509
G	HOH515
G	HOH544

site_id	AE2
Number of Residues	4
Details	binding site for residue MLI H 401

Chain	Residue
H	TRP268
H	SER270
H	HOH501
H	HOH535

site_id	AE3
Number of Residues	3
Details	binding site for residue ACT H 402

Chain	Residue
G	ARG105
H	TRP243
H	HIS245

site_id	AE4
Number of Residues	3
Details	binding site for residue ACT H 403

Chain	Residue
E	HOH577
H	SER322
H	HOH586

site_id	AE5
Number of Residues	1
Details	binding site for residue ACT H 404

Chain	Residue
H	GLY50

Functional Information from PROSITE/UniProt

site_id	PS01330
Number of Residues	14
Details	PABS_1 Polyamine biosynthesis (PABS) domain signature. VLVIGGGdGgvLrE

Chain	Residue	Details
A	VAL128-GLU141

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: Proton acceptor => ECO:0000250

Chain	Residue	Details
A	ASP205
B	ASP205
C	ASP205
D	ASP205
E	ASP205
F	ASP205
G	ASP205
H	ASP205

site_id	SWS_FT_FI2
Number of Residues	64
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	GLN80
B	TYR110
B	GLN111
B	ASP135
B	GLU155
B	ASP186
B	ASP205
B	TYR274
C	GLN80
C	TYR110
C	GLN111
A	TYR110
C	ASP135
C	GLU155
C	ASP186
C	ASP205
C	TYR274
D	GLN80
D	TYR110
D	GLN111
D	ASP135
D	GLU155
A	GLN111
D	ASP186
D	ASP205
D	TYR274
E	GLN80
E	TYR110
E	GLN111
E	ASP135
E	GLU155
E	ASP186
E	ASP205
A	ASP135
E	TYR274
F	GLN80
F	TYR110
F	GLN111
F	ASP135
F	GLU155
F	ASP186
F	ASP205
F	TYR274
G	GLN80
A	GLU155
G	TYR110
G	GLN111
G	ASP135
G	GLU155
G	ASP186
G	ASP205
G	TYR274
H	GLN80
H	TYR110
H	GLN111
A	ASP186
H	ASP135
H	GLU155
H	ASP186
H	ASP205
H	TYR274
A	ASP205
A	TYR274
B	GLN80

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)