6O0W

Crystal structure of the TIR domain from the grapevine disease resistance protein RUN1 in complex with NADP+ and Bis-Tris

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0007165	biological_process	signal transduction

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue A2P A 201

Chain	Residue
A	ARG34
A	HOH307
A	HOH315
A	HOH319
A	HOH330
A	GLY35
A	GLU36
A	ARG39
A	ARG64
A	ARG65
A	GLY66
A	TRP96
A	BTB202

---

site_id	AC2
Number of Residues	10
Details	binding site for residue BTB A 202

Chain	Residue
A	PHE33
A	GLY35
A	ASP60
A	ARG64
A	LEU73
A	CYS97
A	GLU100
A	A2P201
A	HOH310
A	HOH316

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	165
Details	Domain: {"description":"TIR","evidences":[{"source":"PROSITE-ProRule","id":"PRU00204","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00204","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"31439792","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31439792","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6O0W","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---