6NWV

Insulin Lispro Analog

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005179	molecular_function	hormone activity
A	0005576	cellular_component	extracellular region
B	0005179	molecular_function	hormone activity
B	0005576	cellular_component	extracellular region
C	0005179	molecular_function	hormone activity
C	0005576	cellular_component	extracellular region
D	0005179	molecular_function	hormone activity
D	0005576	cellular_component	extracellular region
E	0005179	molecular_function	hormone activity
E	0005576	cellular_component	extracellular region
F	0005179	molecular_function	hormone activity
F	0005576	cellular_component	extracellular region
G	0005179	molecular_function	hormone activity
G	0005576	cellular_component	extracellular region
H	0005179	molecular_function	hormone activity
H	0005576	cellular_component	extracellular region
I	0005179	molecular_function	hormone activity
I	0005576	cellular_component	extracellular region
J	0005179	molecular_function	hormone activity
J	0005576	cellular_component	extracellular region
K	0005179	molecular_function	hormone activity
K	0005576	cellular_component	extracellular region
L	0005179	molecular_function	hormone activity
L	0005576	cellular_component	extracellular region

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue CRS A 101

Chain	Residue
A	CYS6
A	SER9
A	ILE10
A	CYS11
B	LEU11
F	LEU17

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN B 101

Chain	Residue
L	CL101
B	HIS10
D	HIS10
L	HIS10

---

site_id	AC3
Number of Residues	6
Details	binding site for residue CRS C 101

Chain	Residue
C	CYS6
C	ILE10
C	CYS11
D	LEU11
J	LEU17
L	LEU6

---

site_id	AC4
Number of Residues	6
Details	binding site for residue GOL D 101

Chain	Residue
C	CYS7
D	ASN3
D	CYS7
D	HOH205
L	ASN3
L	HOH210

---

site_id	AC5
Number of Residues	6
Details	binding site for residue CRS E 101

Chain	Residue
B	LEU17
E	CYS6
E	ILE10
E	CYS11
F	HIS10
F	LEU11

---

site_id	AC6
Number of Residues	4
Details	binding site for residue ZN F 101

Chain	Residue
F	HIS10
H	HIS10
J	HIS10
J	CL101

---

site_id	AC7
Number of Residues	8
Details	binding site for residue GOL F 102

Chain	Residue
A	ILE10
A	CYS11
A	SER12
D	HIS5
F	TYR16
F	LEU17
F	GLY20
F	HOH201

---

site_id	AC8
Number of Residues	9
Details	binding site for residue CRS G 101

Chain	Residue
G	CYS6
G	SER9
G	ILE10
G	CYS11
G	LEU16
H	LEU11
H	ALA14
J	LEU6
L	LEU17

---

site_id	AC9
Number of Residues	5
Details	binding site for residue CRS G 102

Chain	Residue
G	LEU13
G	TYR14
K	LEU13
K	TYR14
K	GLU17

---

site_id	AD1
Number of Residues	7
Details	binding site for residue CRS I 101

Chain	Residue
D	LEU17
I	CYS6
I	SER9
I	ILE10
I	CYS11
I	LEU16
J	LEU11

---

site_id	AD2
Number of Residues	4
Details	binding site for residue CL J 101

Chain	Residue
F	HIS10
F	ZN101
H	HIS10
J	HIS10

---

site_id	AD3
Number of Residues	7
Details	binding site for residue CRS K 101

Chain	Residue
B	HIS5
H	LEU17
K	CYS6
K	SER9
K	ILE10
K	CYS11
L	LEU11

---

site_id	AD4
Number of Residues	4
Details	binding site for residue CL L 101

Chain	Residue
B	HIS10
B	ZN101
D	HIS10
L	HIS10

---

Functional Information from PROSITE/UniProt

site_id	PS00262
Number of Residues	15
Details	INSULIN Insulin family signature. CCTSiCSlyqLenyC

Chain	Residue	Details
A	CYS6-CYS20

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	120
Details	Peptide: {"description":"Insulin A chain","featureId":"PRO_0000015821"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	116
Details	Peptide: {"description":"Insulin B chain","featureId":"PRO_0000015819"}

Chain

Residue

Details

---