6NV1
Structure of drug-resistant V27A mutant of the influenza M2 proton channel bound to spiroadamantyl amine inhibitor
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0015078 | molecular_function | proton transmembrane transporter activity |
A | 0033644 | cellular_component | host cell membrane |
A | 0055036 | cellular_component | virion membrane |
A | 1902600 | biological_process | proton transmembrane transport |
B | 0015078 | molecular_function | proton transmembrane transporter activity |
B | 0033644 | cellular_component | host cell membrane |
B | 0055036 | cellular_component | virion membrane |
B | 1902600 | biological_process | proton transmembrane transport |
C | 0015078 | molecular_function | proton transmembrane transporter activity |
C | 0033644 | cellular_component | host cell membrane |
C | 0055036 | cellular_component | virion membrane |
C | 1902600 | biological_process | proton transmembrane transport |
D | 0015078 | molecular_function | proton transmembrane transporter activity |
D | 0033644 | cellular_component | host cell membrane |
D | 0055036 | cellular_component | virion membrane |
D | 1902600 | biological_process | proton transmembrane transport |
E | 0015078 | molecular_function | proton transmembrane transporter activity |
E | 0033644 | cellular_component | host cell membrane |
E | 0055036 | cellular_component | virion membrane |
E | 1902600 | biological_process | proton transmembrane transport |
F | 0015078 | molecular_function | proton transmembrane transporter activity |
F | 0033644 | cellular_component | host cell membrane |
F | 0055036 | cellular_component | virion membrane |
F | 1902600 | biological_process | proton transmembrane transport |
G | 0015078 | molecular_function | proton transmembrane transporter activity |
G | 0033644 | cellular_component | host cell membrane |
G | 0055036 | cellular_component | virion membrane |
G | 1902600 | biological_process | proton transmembrane transport |
H | 0015078 | molecular_function | proton transmembrane transporter activity |
H | 0033644 | cellular_component | host cell membrane |
H | 0055036 | cellular_component | virion membrane |
H | 1902600 | biological_process | proton transmembrane transport |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue OLC A 101 |
Chain | Residue |
B | ARG45 |
C | VAL28 |
C | ILE32 |
C | ILE33 |
site_id | AC2 |
Number of Residues | 8 |
Details | binding site for residue E01 A 102 |
Chain | Residue |
B | SER31 |
D | ALA30 |
D | SER31 |
A | ALA27 |
A | ALA30 |
A | SER31 |
A | HOH201 |
A | HOH202 |
site_id | AC3 |
Number of Residues | 8 |
Details | binding site for residue OLC B 101 |
Chain | Residue |
B | LEU40 |
B | LEU43 |
B | ASP44 |
C | LEU46 |
G | LEU46 |
H | VAL28 |
H | ILE32 |
H | ILE33 |
site_id | AC4 |
Number of Residues | 7 |
Details | binding site for residue OLC D 101 |
Chain | Residue |
A | PRO25 |
A | ALA29 |
C | LEU40 |
C | ASP44 |
D | TRP41 |
D | ARG45 |
H | LEU43 |
site_id | AC5 |
Number of Residues | 6 |
Details | binding site for residue OLC E 101 |
Chain | Residue |
E | LEU36 |
G | PRO25 |
G | VAL28 |
G | ALA29 |
G | ILE32 |
G | ILE33 |
site_id | AC6 |
Number of Residues | 3 |
Details | binding site for residue OLC E 102 |
Chain | Residue |
E | TRP41 |
E | LEU46 |
H | ASP44 |
site_id | AC7 |
Number of Residues | 4 |
Details | binding site for residue OLC F 101 |
Chain | Residue |
A | LEU46 |
F | ALA29 |
F | ILE32 |
F | ILE33 |
site_id | AC8 |
Number of Residues | 8 |
Details | binding site for residue E01 F 102 |
Chain | Residue |
F | ALA27 |
F | ALA30 |
F | SER31 |
F | HOH202 |
F | HOH203 |
G | ALA27 |
G | SER31 |
H | SER31 |
site_id | AC9 |
Number of Residues | 2 |
Details | binding site for residue OLC G 101 |
Chain | Residue |
G | ARG45 |
G | LEU46 |
site_id | AD1 |
Number of Residues | 3 |
Details | binding site for residue OLC H 101 |
Chain | Residue |
E | ILE32 |
G | ASP44 |
H | LEU46 |
site_id | AD2 |
Number of Residues | 1 |
Details | binding site for residue CL H 102 |
Chain | Residue |
H | TRP41 |
site_id | AD3 |
Number of Residues | 4 |
Details | binding site for Di-peptide LEU B 46 and NH2 B 47 |
Chain | Residue |
B | ILE42 |
B | LEU43 |
B | ASP44 |
B | ARG45 |
site_id | AD4 |
Number of Residues | 6 |
Details | binding site for Di-peptide LEU C 46 and NH2 C 47 |
Chain | Residue |
B | OLC101 |
C | ILE42 |
C | LEU43 |
C | ASP44 |
C | ARG45 |
D | PRO25 |
site_id | AD5 |
Number of Residues | 5 |
Details | binding site for Di-peptide LEU D 46 and NH2 D 47 |
Chain | Residue |
D | ILE42 |
D | LEU43 |
D | ASP44 |
D | ARG45 |
E | PRO25 |
site_id | AD6 |
Number of Residues | 5 |
Details | binding site for Di-peptide LEU E 46 and NH2 E 47 |
Chain | Residue |
E | ILE42 |
E | LEU43 |
E | ASP44 |
E | ARG45 |
E | OLC102 |
site_id | AD7 |
Number of Residues | 4 |
Details | binding site for Di-peptide LEU F 46 and NH2 F 47 |
Chain | Residue |
F | ILE42 |
F | LEU43 |
F | ASP44 |
F | ARG45 |
site_id | AD8 |
Number of Residues | 7 |
Details | binding site for Di-peptide LEU G 46 and NH2 G 47 |
Chain | Residue |
B | OLC101 |
G | ILE42 |
G | LEU43 |
G | ASP44 |
G | ARG45 |
G | OLC101 |
H | PRO25 |
site_id | AD9 |
Number of Residues | 6 |
Details | binding site for Di-peptide LEU H 46 and NH2 H 47 |
Chain | Residue |
A | PRO25 |
H | ILE42 |
H | LEU43 |
H | ASP44 |
H | ARG45 |
H | OLC101 |