6NPM
Crystal structure of Epstein-Barr Virus Nuclear Antigen-1, EBNA1, bound to fragments
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006275 | biological_process | regulation of DNA replication |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0042025 | cellular_component | host cell nucleus |
| A | 0045893 | biological_process | positive regulation of DNA-templated transcription |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006275 | biological_process | regulation of DNA replication |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0042025 | cellular_component | host cell nucleus |
| B | 0045893 | biological_process | positive regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue KVD B 701 |
| Chain | Residue |
| B | ASN480 |
| B | THR590 |
| B | HOH819 |
| B | HOH831 |
| B | HOH833 |
| B | HOH915 |
| B | ILE481 |
| B | GLY484 |
| B | SER516 |
| B | ASN519 |
| B | LEU520 |
| B | LEU582 |
| B | THR585 |
| B | LYS586 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"For site-specific DNA endonuclease activity","evidences":[{"source":"PubMed","id":"33482082","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"33482082","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Interaction dimer-dimer","evidences":[{"source":"PubMed","id":"31142669","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Interaction dimer-dimer. Required for episome maintenance and generation of immortalized B cells in the host","evidences":[{"source":"PubMed","id":"31142669","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33482082","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
