6NP1
Product state mimicry leads to aminoglycoside discrimination in an antibiotic acetyltransferase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008080 | molecular_function | N-acetyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0046353 | molecular_function | aminoglycoside 3-N-acetyltransferase activity |
| A | 0046677 | biological_process | response to antibiotic |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue MG A 301 |
| Chain | Residue |
| A | THR71 |
| A | ASP145 |
| A | ASP145 |
| A | HOH460 |
| A | HOH460 |
| A | HOH504 |
| A | HOH504 |
| A | HOH514 |
| A | HOH514 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 302 |
| Chain | Residue |
| A | HOH465 |
| A | HOH521 |
| A | HOH574 |
| A | HOH580 |
| A | HOH581 |
| A | HOH605 |
