6NP1

Product state mimicry leads to aminoglycoside discrimination in an antibiotic acetyltransferase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008080	molecular_function	N-acetyltransferase activity
A	0046353	molecular_function	aminoglycoside 3-N-acetyltransferase activity
A	0046677	biological_process	response to antibiotic

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue MG A 301

Chain	Residue
A	THR71
A	ASP145
A	ASP145
A	HOH460
A	HOH460
A	HOH504
A	HOH504
A	HOH514
A	HOH514

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site_id	AC2
Number of Residues	6
Details	binding site for residue MG A 302

Chain	Residue
A	HOH465
A	HOH521
A	HOH574
A	HOH580
A	HOH581
A	HOH605

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