6NIG

Crystal structure of the human TLR2-Diprovocim complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002224	biological_process	toll-like receptor signaling pathway
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0006955	biological_process	immune response
A	0016020	cellular_component	membrane
B	0002224	biological_process	toll-like receptor signaling pathway
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0006955	biological_process	immune response
B	0016020	cellular_component	membrane
C	0002224	biological_process	toll-like receptor signaling pathway
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0006955	biological_process	immune response
C	0016020	cellular_component	membrane
D	0002224	biological_process	toll-like receptor signaling pathway
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0006955	biological_process	immune response
D	0016020	cellular_component	membrane

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	SITE: Interaction with bacterial lipopeptide

Chain	Residue	Details
A	PHE349
B	PHE349
C	PHE349
D	PHE349

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15173186, ECO:0000269|PubMed:17889651

Chain	Residue	Details
A	ASN114
D	ASN114
D	ASN199
D	ASN442
A	ASN199
A	ASN442
B	ASN114
B	ASN199
B	ASN442
C	ASN114
C	ASN199
C	ASN442

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17889651

Chain	Residue	Details
A	ASN414
B	ASN414
C	ASN414
D	ASN414

---