6ND4

Conformational switches control early maturation of the eukaryotic small ribosomal subunit

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A	0000480	biological_process	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A	0003674	molecular_function	molecular_function
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005730	cellular_component	nucleolus
A	0005732	cellular_component	sno(s)RNA-containing ribonucleoprotein complex
A	0006364	biological_process	rRNA processing
A	0030490	biological_process	maturation of SSU-rRNA
A	0030686	cellular_component	90S preribosome
A	0032040	cellular_component	small-subunit processome
A	0034457	cellular_component	Mpp10 complex
A	0042254	biological_process	ribosome biogenesis
A	0042802	molecular_function	identical protein binding
A	1990904	cellular_component	ribonucleoprotein complex
D	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D	0005730	cellular_component	nucleolus
D	0006364	biological_process	rRNA processing
D	0030490	biological_process	maturation of SSU-rRNA
D	0030515	molecular_function	snoRNA binding
D	0030686	cellular_component	90S preribosome
D	0032040	cellular_component	small-subunit processome
D	0034511	molecular_function	U3 snoRNA binding
D	0042254	biological_process	ribosome biogenesis
D	1990904	cellular_component	ribonucleoprotein complex
H	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H	0003723	molecular_function	RNA binding
H	0003729	molecular_function	mRNA binding
H	0005515	molecular_function	protein binding
H	0005654	cellular_component	nucleoplasm
H	0005730	cellular_component	nucleolus
H	0005777	cellular_component	peroxisome
H	0006364	biological_process	rRNA processing
H	0030490	biological_process	maturation of SSU-rRNA
H	0030686	cellular_component	90S preribosome
H	0032040	cellular_component	small-subunit processome
H	0033553	cellular_component	rDNA heterochromatin
H	0034455	cellular_component	t-UTP complex
H	0034511	molecular_function	U3 snoRNA binding
H	0042254	biological_process	ribosome biogenesis
H	0045943	biological_process	positive regulation of transcription by RNA polymerase I
H	1990904	cellular_component	ribonucleoprotein complex
H	2000234	biological_process	positive regulation of rRNA processing
J	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J	0005515	molecular_function	protein binding
J	0005654	cellular_component	nucleoplasm
J	0005730	cellular_component	nucleolus
J	0006364	biological_process	rRNA processing
J	0030490	biological_process	maturation of SSU-rRNA
J	0030686	cellular_component	90S preribosome
J	0032040	cellular_component	small-subunit processome
J	0033553	cellular_component	rDNA heterochromatin
J	0034455	cellular_component	t-UTP complex
J	0034511	molecular_function	U3 snoRNA binding
J	0042254	biological_process	ribosome biogenesis
J	0045943	biological_process	positive regulation of transcription by RNA polymerase I
J	1990904	cellular_component	ribonucleoprotein complex
L	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L	0003674	molecular_function	molecular_function
L	0005515	molecular_function	protein binding
L	0005654	cellular_component	nucleoplasm
L	0005730	cellular_component	nucleolus
L	0006364	biological_process	rRNA processing
L	0030490	biological_process	maturation of SSU-rRNA
L	0032040	cellular_component	small-subunit processome
L	0033553	cellular_component	rDNA heterochromatin
L	0034455	cellular_component	t-UTP complex
L	0042254	biological_process	ribosome biogenesis
L	0045943	biological_process	positive regulation of transcription by RNA polymerase I
L	1990904	cellular_component	ribonucleoprotein complex
M	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
M	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
M	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
M	0000480	biological_process	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
M	0005515	molecular_function	protein binding
M	0005654	cellular_component	nucleoplasm
M	0005730	cellular_component	nucleolus
M	0005739	cellular_component	mitochondrion
M	0006364	biological_process	rRNA processing
M	0030490	biological_process	maturation of SSU-rRNA
M	0030515	molecular_function	snoRNA binding
M	0030686	cellular_component	90S preribosome
M	0030688	cellular_component	preribosome, small subunit precursor
M	0032040	cellular_component	small-subunit processome
M	0033553	cellular_component	rDNA heterochromatin
M	0034455	cellular_component	t-UTP complex
M	0034511	molecular_function	U3 snoRNA binding
M	0042254	biological_process	ribosome biogenesis
M	0045943	biological_process	positive regulation of transcription by RNA polymerase I
M	1990904	cellular_component	ribonucleoprotein complex
N	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
N	0003674	molecular_function	molecular_function
N	0005515	molecular_function	protein binding
N	0005654	cellular_component	nucleoplasm
N	0005730	cellular_component	nucleolus
N	0006364	biological_process	rRNA processing
N	0030490	biological_process	maturation of SSU-rRNA
N	0030686	cellular_component	90S preribosome
N	0032040	cellular_component	small-subunit processome
N	0034455	cellular_component	t-UTP complex
N	0042254	biological_process	ribosome biogenesis
N	0045943	biological_process	positive regulation of transcription by RNA polymerase I
N	1990904	cellular_component	ribonucleoprotein complex
O	0000028	biological_process	ribosomal small subunit assembly
O	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
O	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
O	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
O	0000480	biological_process	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
O	0000920	biological_process	septum digestion after cytokinesis
O	0003729	molecular_function	mRNA binding
O	0005515	molecular_function	protein binding
O	0005654	cellular_component	nucleoplasm
O	0005730	cellular_component	nucleolus
O	0005737	cellular_component	cytoplasm
O	0006364	biological_process	rRNA processing
O	0030010	biological_process	establishment of cell polarity
O	0030490	biological_process	maturation of SSU-rRNA
O	0030686	cellular_component	90S preribosome
O	0032040	cellular_component	small-subunit processome
O	0034388	cellular_component	Pwp2p-containing subcomplex of 90S preribosome
O	0042254	biological_process	ribosome biogenesis
O	1990904	cellular_component	ribonucleoprotein complex
P	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
P	0006396	biological_process	RNA processing
P	0030515	molecular_function	snoRNA binding
Q	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Q	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Q	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Q	0000480	biological_process	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Q	0005515	molecular_function	protein binding
Q	0005654	cellular_component	nucleoplasm
Q	0005730	cellular_component	nucleolus
Q	0006364	biological_process	rRNA processing
Q	0030490	biological_process	maturation of SSU-rRNA
Q	0030515	molecular_function	snoRNA binding
Q	0030686	cellular_component	90S preribosome
Q	0032040	cellular_component	small-subunit processome
Q	0034388	cellular_component	Pwp2p-containing subcomplex of 90S preribosome
Q	0034511	molecular_function	U3 snoRNA binding
Q	0042254	biological_process	ribosome biogenesis
Q	1990904	cellular_component	ribonucleoprotein complex
R	0006364	biological_process	rRNA processing
R	0032040	cellular_component	small-subunit processome
S	0000292	biological_process	RNA fragment catabolic process
S	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
S	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
S	0000480	biological_process	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
S	0003674	molecular_function	molecular_function
S	0005515	molecular_function	protein binding
S	0005654	cellular_component	nucleoplasm
S	0005730	cellular_component	nucleolus
S	0006364	biological_process	rRNA processing
S	0030490	biological_process	maturation of SSU-rRNA
S	0030686	cellular_component	90S preribosome
S	0032040	cellular_component	small-subunit processome
S	0034388	cellular_component	Pwp2p-containing subcomplex of 90S preribosome
S	0042254	biological_process	ribosome biogenesis
S	1990904	cellular_component	ribonucleoprotein complex
T	0003674	molecular_function	molecular_function
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005730	cellular_component	nucleolus
T	0006364	biological_process	rRNA processing
T	0030490	biological_process	maturation of SSU-rRNA
T	0030686	cellular_component	90S preribosome
T	0032040	cellular_component	small-subunit processome
T	0034388	cellular_component	Pwp2p-containing subcomplex of 90S preribosome
T	0042254	biological_process	ribosome biogenesis
T	1990904	cellular_component	ribonucleoprotein complex
U	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
U	0003729	molecular_function	mRNA binding
U	0005654	cellular_component	nucleoplasm
U	0005730	cellular_component	nucleolus
U	0006364	biological_process	rRNA processing
U	0030490	biological_process	maturation of SSU-rRNA
U	0030686	cellular_component	90S preribosome
U	0032040	cellular_component	small-subunit processome
U	0042254	biological_process	ribosome biogenesis
U	1990904	cellular_component	ribonucleoprotein complex
W	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
W	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
W	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
W	0000480	biological_process	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
W	0003674	molecular_function	molecular_function
W	0005515	molecular_function	protein binding
W	0005654	cellular_component	nucleoplasm
W	0005730	cellular_component	nucleolus
W	0006364	biological_process	rRNA processing
W	0030490	biological_process	maturation of SSU-rRNA
W	0030686	cellular_component	90S preribosome
W	0030688	cellular_component	preribosome, small subunit precursor
W	0032040	cellular_component	small-subunit processome
W	0042254	biological_process	ribosome biogenesis
W	1990904	cellular_component	ribonucleoprotein complex
Z	0003723	molecular_function	RNA binding
Z	0005515	molecular_function	protein binding
Z	0005654	cellular_component	nucleoplasm
Z	0005730	cellular_component	nucleolus
Z	0006364	biological_process	rRNA processing
Z	0019843	molecular_function	rRNA binding
Z	0030490	biological_process	maturation of SSU-rRNA
Z	0030515	molecular_function	snoRNA binding
Z	0030686	cellular_component	90S preribosome
Z	0032040	cellular_component	small-subunit processome
Z	0034337	biological_process	RNA folding
Z	0034457	cellular_component	Mpp10 complex
Z	0042254	biological_process	ribosome biogenesis
Z	0042274	biological_process	ribosomal small subunit biogenesis
Z	0140691	molecular_function	RNA folding chaperone
Z	1990904	cellular_component	ribonucleoprotein complex
a	0000154	biological_process	rRNA modification
a	0000452	biological_process	snoRNA guided rRNA 2'-O-methylation
a	0000494	biological_process	box C/D sno(s)RNA 3'-end processing
a	0003729	molecular_function	mRNA binding
a	0005515	molecular_function	protein binding
a	0005634	cellular_component	nucleus
a	0005654	cellular_component	nucleoplasm
a	0005730	cellular_component	nucleolus
a	0006364	biological_process	rRNA processing
a	0030490	biological_process	maturation of SSU-rRNA
a	0030515	molecular_function	snoRNA binding
a	0030686	cellular_component	90S preribosome
a	0031428	cellular_component	box C/D methylation guide snoRNP complex
a	0032040	cellular_component	small-subunit processome
a	0042254	biological_process	ribosome biogenesis
a	1990904	cellular_component	ribonucleoprotein complex
b	0030515	molecular_function	snoRNA binding
b	0031428	cellular_component	box C/D methylation guide snoRNP complex
b	0032040	cellular_component	small-subunit processome
c	0000451	biological_process	rRNA 2'-O-methylation
c	0000452	biological_process	snoRNA guided rRNA 2'-O-methylation
c	0000494	biological_process	box C/D sno(s)RNA 3'-end processing
c	0003723	molecular_function	RNA binding
c	0005515	molecular_function	protein binding
c	0005654	cellular_component	nucleoplasm
c	0005730	cellular_component	nucleolus
c	0006338	biological_process	chromatin remodeling
c	0006356	biological_process	regulation of transcription by RNA polymerase I
c	0006364	biological_process	rRNA processing
c	0008168	molecular_function	methyltransferase activity
c	0008171	molecular_function	O-methyltransferase activity
c	0008649	molecular_function	rRNA methyltransferase activity
c	0016740	molecular_function	transferase activity
c	0030490	biological_process	maturation of SSU-rRNA
c	0030686	cellular_component	90S preribosome
c	0031167	biological_process	rRNA methylation
c	0031428	cellular_component	box C/D methylation guide snoRNP complex
c	0032040	cellular_component	small-subunit processome
c	0032259	biological_process	methylation
c	0042254	biological_process	ribosome biogenesis
c	1990259	molecular_function	histone H2AQ104 methyltransferase activity
c	1990904	cellular_component	ribonucleoprotein complex
d	0000451	biological_process	rRNA 2'-O-methylation
d	0000452	biological_process	snoRNA guided rRNA 2'-O-methylation
d	0000494	biological_process	box C/D sno(s)RNA 3'-end processing
d	0003723	molecular_function	RNA binding
d	0005515	molecular_function	protein binding
d	0005654	cellular_component	nucleoplasm
d	0005730	cellular_component	nucleolus
d	0006338	biological_process	chromatin remodeling
d	0006356	biological_process	regulation of transcription by RNA polymerase I
d	0006364	biological_process	rRNA processing
d	0008168	molecular_function	methyltransferase activity
d	0008171	molecular_function	O-methyltransferase activity
d	0008649	molecular_function	rRNA methyltransferase activity
d	0016740	molecular_function	transferase activity
d	0030490	biological_process	maturation of SSU-rRNA
d	0030686	cellular_component	90S preribosome
d	0031167	biological_process	rRNA methylation
d	0031428	cellular_component	box C/D methylation guide snoRNP complex
d	0032040	cellular_component	small-subunit processome
d	0032259	biological_process	methylation
d	0042254	biological_process	ribosome biogenesis
d	1990259	molecular_function	histone H2AQ104 methyltransferase activity
d	1990904	cellular_component	ribonucleoprotein complex
e	0000245	biological_process	spliceosomal complex assembly
e	0000398	biological_process	mRNA splicing, via spliceosome
e	0000452	biological_process	snoRNA guided rRNA 2'-O-methylation
e	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
e	0000494	biological_process	box C/D sno(s)RNA 3'-end processing
e	0003723	molecular_function	RNA binding
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0005654	cellular_component	nucleoplasm
e	0005681	cellular_component	spliceosomal complex
e	0005687	cellular_component	U4 snRNP
e	0005730	cellular_component	nucleolus
e	0006364	biological_process	rRNA processing
e	0006397	biological_process	mRNA processing
e	0008380	biological_process	RNA splicing
e	0030490	biological_process	maturation of SSU-rRNA
e	0030621	molecular_function	U4 snRNA binding
e	0031428	cellular_component	box C/D methylation guide snoRNP complex
e	0032040	cellular_component	small-subunit processome
e	0034511	molecular_function	U3 snoRNA binding
e	0042254	biological_process	ribosome biogenesis
e	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
e	0071001	cellular_component	U4/U6 snRNP
e	0071011	cellular_component	precatalytic spliceosome
e	1990904	cellular_component	ribonucleoprotein complex
f	0000245	biological_process	spliceosomal complex assembly
f	0000398	biological_process	mRNA splicing, via spliceosome
f	0000452	biological_process	snoRNA guided rRNA 2'-O-methylation
f	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
f	0000494	biological_process	box C/D sno(s)RNA 3'-end processing
f	0003723	molecular_function	RNA binding
f	0005515	molecular_function	protein binding
f	0005634	cellular_component	nucleus
f	0005654	cellular_component	nucleoplasm
f	0005681	cellular_component	spliceosomal complex
f	0005687	cellular_component	U4 snRNP
f	0005730	cellular_component	nucleolus
f	0006364	biological_process	rRNA processing
f	0006397	biological_process	mRNA processing
f	0008380	biological_process	RNA splicing
f	0030490	biological_process	maturation of SSU-rRNA
f	0030621	molecular_function	U4 snRNA binding
f	0031428	cellular_component	box C/D methylation guide snoRNP complex
f	0032040	cellular_component	small-subunit processome
f	0034511	molecular_function	U3 snoRNA binding
f	0042254	biological_process	ribosome biogenesis
f	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
f	0071001	cellular_component	U4/U6 snRNP
f	0071011	cellular_component	precatalytic spliceosome
f	1990904	cellular_component	ribonucleoprotein complex
g	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
g	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
g	0000480	biological_process	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
g	0005515	molecular_function	protein binding
g	0005654	cellular_component	nucleoplasm
g	0005730	cellular_component	nucleolus
g	0006364	biological_process	rRNA processing
g	0030490	biological_process	maturation of SSU-rRNA
g	0030515	molecular_function	snoRNA binding
g	0030686	cellular_component	90S preribosome
g	0031428	cellular_component	box C/D methylation guide snoRNP complex
g	0032040	cellular_component	small-subunit processome
g	0034511	molecular_function	U3 snoRNA binding
g	0042254	biological_process	ribosome biogenesis
g	1990904	cellular_component	ribonucleoprotein complex
l	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
l	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
l	0000480	biological_process	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
l	0004521	molecular_function	RNA endonuclease activity
l	0004540	molecular_function	RNA nuclease activity
l	0005515	molecular_function	protein binding
l	0005654	cellular_component	nucleoplasm
l	0005730	cellular_component	nucleolus
l	0006364	biological_process	rRNA processing
l	0008270	molecular_function	zinc ion binding
l	0030490	biological_process	maturation of SSU-rRNA
l	0032040	cellular_component	small-subunit processome
l	0042254	biological_process	ribosome biogenesis
l	0042274	biological_process	ribosomal small subunit biogenesis

Functional Information from PROSITE/UniProt

site_id	PS00178
Number of Residues	11
Details	AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. Pw.NAvMHLGHS

Chain	Residue	Details
W	PRO242-SER252

---

site_id	PS00566
Number of Residues	15
Details	FIBRILLARIN Fibrillarin signature. GVVYAVEFShRpgRE

Chain	Residue	Details
c	GLY192-GLU206

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. MATTgaDrSMKIWDI

Chain	Residue	Details
W	MET289-ILE303
Q	LEU488-PHE502
O	ILE206-PHE220
O	VAL360-ILE374
O	MET402-LEU416
T	ILE600-LEU614
J	LEU140-ILE154
Q	LEU136-LEU150
Q	LEU177-LEU191
Q	LEU405-ILE419

---

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CedknVPYvfVpSRvaLG

Chain	Residue	Details
f	CYS71-GLY88

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	314
Details	Repeat: {"description":"WD 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	276
Details	Repeat: {"description":"WD 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	379
Details	Repeat: {"description":"WD 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	339
Details	Repeat: {"description":"WD 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	214
Details	Repeat: {"description":"WD 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	273
Details	Repeat: {"description":"WD 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	79
Details	Repeat: {"description":"WD 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	69
Details	Repeat: {"description":"WD 8"}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	69
Details	Repeat: {"description":"WD 9"}

Chain

Residue

Details

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site_id	SWS_FT_FI11
Number of Residues	72
Details	Repeat: {"description":"WD 10"}

Chain

Residue

Details

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site_id	SWS_FT_FI12
Number of Residues	39
Details	Repeat: {"description":"WD 11"}

Chain

Residue

Details

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site_id	SWS_FT_FI13
Number of Residues	39
Details	Repeat: {"description":"WD 12"}

Chain

Residue

Details

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site_id	SWS_FT_FI14
Number of Residues	39
Details	Repeat: {"description":"WD 13"}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	38
Details	Repeat: {"description":"WD 14"}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	21
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17330950","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	32
Details	Repeat: {"description":"HAT 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	32
Details	Repeat: {"description":"HAT 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	32
Details	Repeat: {"description":"HAT 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	31
Details	Repeat: {"description":"WD 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	30
Details	Repeat: {"description":"WD 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	39
Details	Repeat: {"description":"WD 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	33
Details	Repeat: {"description":"WD 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	37
Details	Repeat: {"description":"WD 5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	35
Details	Repeat: {"description":"WD 6","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	52
Details	Repeat: {"description":"WD 7","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	34
Details	Repeat: {"description":"WD 8","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	39
Details	Repeat: {"description":"WD 9","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	34
Details	Repeat: {"description":"WD 10","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	36
Details	Repeat: {"description":"WD 11","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	35
Details	Repeat: {"description":"WD 12","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	41
Details	Repeat: {"description":"WD 13","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	38
Details	Repeat: {"description":"WD 14","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	14
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	2
Details	Region: {"description":"S-adenosyl-L-methionine binding","evidences":[{"source":"UniProtKB","id":"Q9Y9U3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	10
Details	Region: {"description":"S-adenosyl-L-methionine binding","evidences":[{"source":"UniProtKB","id":"P22087","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI40
Number of Residues	64
Details	Region: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI41
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22106047","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---