6NCS

Crystal structure of N-acetylneuraminic acid (Sialic acid) synthetase from Leptospira borgpetersenii serovar Hardjo-bovis in complex with citrate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016051	biological_process	carbohydrate biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0047444	molecular_function	N-acylneuraminate-9-phosphate synthase activity
B	0016051	biological_process	carbohydrate biosynthetic process
B	0046872	molecular_function	metal ion binding
B	0047444	molecular_function	N-acylneuraminate-9-phosphate synthase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue MN A 301

Chain	Residue
A	HIS202
A	HIS223
A	CIT302
A	HOH410

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site_id	AC2
Number of Residues	15
Details	binding site for residue CIT A 302

Chain	Residue
A	SER120
A	TYR174
A	HIS202
A	HIS223
A	MN301
A	HOH410
A	HOH421
A	HOH486
A	HOH507
A	HOH520
A	GLU23
A	LYS51
A	THR98
A	LYS117
A	ALA119

---

site_id	AC3
Number of Residues	3
Details	binding site for residue ACT A 303

Chain	Residue
A	ILE5
A	THR6
A	HOH557

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site_id	AC4
Number of Residues	1
Details	binding site for residue FMT A 304

Chain	Residue
A	SER191

---

site_id	AC5
Number of Residues	3
Details	binding site for residue TAR A 305

Chain	Residue
A	GLU207
A	LEU210
B	GLU207

---

site_id	AC6
Number of Residues	3
Details	binding site for residue IOD A 307

Chain	Residue
A	GLN89
A	LEU94
A	PHE95

---

site_id	AC7
Number of Residues	1
Details	binding site for residue IOD A 308

Chain	Residue
A	LYS78

---

site_id	AC8
Number of Residues	3
Details	binding site for residue IOD A 310

Chain	Residue
A	GLU243
A	HOH534
A	HOH614

---

site_id	AC9
Number of Residues	2
Details	binding site for residue IOD A 311

Chain	Residue
A	HIS-1
A	LEU263

---

site_id	AD1
Number of Residues	1
Details	binding site for residue IOD A 313

Chain	Residue
A	LYS90

---

site_id	AD2
Number of Residues	1
Details	binding site for residue IOD A 314

Chain	Residue
A	GLU194

---

site_id	AD3
Number of Residues	4
Details	binding site for residue MN B 301

Chain	Residue
B	HIS202
B	HIS223
B	CIT302
B	HOH405

---

site_id	AD4
Number of Residues	15
Details	binding site for residue CIT B 302

Chain	Residue
B	GLU23
B	LYS51
B	GLN53
B	THR98
B	LYS117
B	ALA119
B	SER120
B	TYR174
B	HIS202
B	HIS223
B	MN301
B	HOH405
B	HOH424
B	HOH546
B	HOH558

---

site_id	AD5
Number of Residues	3
Details	binding site for residue IOD B 304

Chain	Residue
B	LEU94
B	PHE95
B	HOH419

---

site_id	AD6
Number of Residues	2
Details	binding site for residue IOD B 305

Chain	Residue
B	LYS78
B	MET107

---

site_id	AD7
Number of Residues	1
Details	binding site for residue IOD B 306

Chain	Residue
B	GLU194

---

site_id	AD8
Number of Residues	2
Details	binding site for residue IOD B 307

Chain	Residue
A	LYS192
B	LEU263

---

site_id	AD9
Number of Residues	1
Details	binding site for residue IOD B 309

Chain	Residue
B	HOH543

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