6NCO
Fragment-based Discovery of an apoE4 Stabilizer
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue KQP A 201 |
| Chain | Residue |
| A | GLU27 |
| A | GLN156 |
| A | HOH374 |
| A | LEU30 |
| A | GLY31 |
| A | TRP34 |
| A | ASP35 |
| A | GLU131 |
| A | ARG134 |
| A | LEU149 |
| A | ASP153 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:3947350 |
| Chain | Residue | Details |
| A | LYS143 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Methionine sulfoxide => ECO:0000250|UniProtKB:P08226 |
| Chain | Residue | Details |
| A | ALA124 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by FAM20C => ECO:0000269|PubMed:26091039, ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | GLN128 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | CARBOHYD: O-linked (GalNAc...) threonine => ECO:0000269|PubMed:23234360 |
| Chain | Residue | Details |
| A | GLU7 | |
| A | GLN17 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (Glc) (glycation) lysine => ECO:0000269|PubMed:10452964 |
| Chain | Residue | Details |
| A | TYR74 |
