6N6I
Human REXO2 bound to pGG
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 301 |
| Chain | Residue |
| A | ASN110 |
| D | G604 |
| A | LYS158 |
| A | ALA160 |
| A | HIS162 |
| A | ASP167 |
| A | HOH404 |
| A | HOH501 |
| A | HOH538 |
| D | G603 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue NA D 701 |
| Chain | Residue |
| A | ASP15 |
| A | HOH433 |
| A | HOH493 |
| A | HOH501 |
| D | G603 |
| D | G604 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 301 |
| Chain | Residue |
| A | GLN86 |
| A | GLU89 |
| A | PRO124 |
| A | GLN125 |
| B | GLU45 |
| B | SER169 |
| B | HOH429 |
| B | HOH434 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue MLI B 302 |
| Chain | Residue |
| A | LYS186 |
| B | ARG97 |
| B | PRO102 |
| B | GLU151 |
| B | HOH406 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 701 |
| Chain | Residue |
| B | ASN110 |
| B | ASP167 |
| C | G603 |
| C | G604 |
| C | HOH806 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue NA C 702 |
| Chain | Residue |
| B | ASP15 |
| B | HOH480 |
| C | G603 |
| C | G604 |
| C | HOH801 |
| C | HOH806 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 328 |
| Details | Domain: {"description":"Exonuclease"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"30926754","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31588022","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30926754","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31588022","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6J7Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RCN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30926754","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31588022","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6RCN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30926754","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6J7Y","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | Site: {"description":"Important for dinucleotide binding","evidences":[{"source":"PubMed","id":"30926754","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32365187","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9D8S4","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
