6N1H

Cryo-EM structure of ASC-CARD filament

Replaces:  6DRN

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006954	biological_process	inflammatory response
A	0042981	biological_process	regulation of apoptotic process
A	0045087	biological_process	innate immune response
B	0006954	biological_process	inflammatory response
B	0042981	biological_process	regulation of apoptotic process
B	0045087	biological_process	innate immune response
C	0006954	biological_process	inflammatory response
C	0042981	biological_process	regulation of apoptotic process
C	0045087	biological_process	innate immune response
D	0006954	biological_process	inflammatory response
D	0042981	biological_process	regulation of apoptotic process
D	0045087	biological_process	innate immune response
E	0006954	biological_process	inflammatory response
E	0042981	biological_process	regulation of apoptotic process
E	0045087	biological_process	innate immune response
F	0006954	biological_process	inflammatory response
F	0042981	biological_process	regulation of apoptotic process
F	0045087	biological_process	innate immune response
G	0006954	biological_process	inflammatory response
G	0042981	biological_process	regulation of apoptotic process
G	0045087	biological_process	innate immune response
H	0006954	biological_process	inflammatory response
H	0042981	biological_process	regulation of apoptotic process
H	0045087	biological_process	innate immune response
I	0006954	biological_process	inflammatory response
I	0042981	biological_process	regulation of apoptotic process
I	0045087	biological_process	innate immune response
J	0006954	biological_process	inflammatory response
J	0042981	biological_process	regulation of apoptotic process
J	0045087	biological_process	innate immune response
K	0006954	biological_process	inflammatory response
K	0042981	biological_process	regulation of apoptotic process
K	0045087	biological_process	innate immune response
L	0006954	biological_process	inflammatory response
L	0042981	biological_process	regulation of apoptotic process
L	0045087	biological_process	innate immune response
M	0006954	biological_process	inflammatory response
M	0042981	biological_process	regulation of apoptotic process
M	0045087	biological_process	innate immune response
N	0006954	biological_process	inflammatory response
N	0042981	biological_process	regulation of apoptotic process
N	0045087	biological_process	innate immune response
O	0006954	biological_process	inflammatory response
O	0042981	biological_process	regulation of apoptotic process
O	0045087	biological_process	innate immune response
P	0006954	biological_process	inflammatory response
P	0042981	biological_process	regulation of apoptotic process
P	0045087	biological_process	innate immune response

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:25847972

Chain	Residue	Details
A	LYS174
F	LYS174
G	LYS174
H	LYS174
I	LYS174
J	LYS174
K	LYS174
L	LYS174
M	LYS174
N	LYS174
O	LYS174
B	LYS174
P	LYS174
C	LYS174
D	LYS174
E	LYS174

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